glycogen synthase kinase 3 alpha

詳細情報を見る

同義遺伝子名

Glycogen synthase kinase-3 alpha, GSK3A, glycogen synthase kinase 3 alpha, GSK-3 alpha, DKFZp686D0638

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:73.50 小脳:50.40 脳幹:- 脳梁:29.20 松果体:- 末梢神経:122.70 脊柱:112.30 網膜:- 目:170.40 動脈:- 静脈:66.60 リンパ節:121.30 末梢血:18.20 脾臓:94.50 胸腺:25.80 骨髄:118.10 脂肪:- 骨:25.60 皮膚:62.40
GeneChip 大脳:6.72 小脳:6.68 脳幹:6.71 脳梁:6.50 松果体:- 末梢神経:6.64 脊柱:6.60 網膜:- 目:- 動脈:6.79 静脈:6.64 リンパ節:6.49 末梢血:- 脾臓:6.36 胸腺:6.34 骨髄:6.75 脂肪:6.64 骨:- 皮膚:6.52
CAGE 大脳:4.20 小脳:- 脳幹:4.13 脳梁:4.22 松果体:3.67 末梢神経:- 脊柱:3.58 網膜:- 目:- 動脈:3.58 静脈:3.59 リンパ節:3.38 末梢血:- 脾臓:3.48 胸腺:3.61 骨髄:- 脂肪:3.26 骨:- 皮膚:-
RNA-seq 大脳:4.81 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.68 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.79 骨:- 皮膚:-
EST 子宮:45.60 胎盤:87.40 前立腺:56.30 卵巣:74.50 精巣:51.90 心臓:63.90 骨格筋:20.10 食道:- 胃:42.50 腸:64.80 結腸:288.30     肝臓:-        肺:63.50    膀胱:125.60 腎臓:187.10 下垂体:- 甲状腺:- 副腎:- 膵臓:71.10 乳腺:83.60 唾液腺:328.40
GeneChip 子宮:6.49 胎盤:6.57 前立腺:6.37 卵巣:6.32 精巣:6.62 心臓:6.52 骨格筋:6.59 食道:6.64 胃:6.54 腸:6.82 結腸:6.68 肝臓:6.57 肺:6.44 膀胱:- 腎臓:6.53 下垂体:6.93 甲状腺:6.53 副腎:6.54 膵臓:7.35 乳腺:6.36 唾液腺:6.30
CAGE 子宮:3.47 胎盤:3.61 前立腺:3.67 卵巣:3.49 精巣:3.95 心臓:3.51 骨格筋:3.59 食道:3.58 胃:- 腸:4.13 結腸:3.72     肝臓:3.39    肺:3.46 膀胱:3.45 腎臓:3.67 下垂体:3.19 甲状腺:3.71 副腎:- 膵臓:3.34 乳腺:3.60 唾液腺:3.42
RNA-seq 子宮:- 胎盤:- 前立腺:4.87 卵巣:3.93 精巣:4.67 心臓:3.82 骨格筋:5.35 食道:- 胃:- 腸:- 結腸:4.10     肝臓:3.52        肺:4.55    膀胱:- 腎臓:4.14 下垂体:- 甲状腺:4.23 副腎:3.68 膵臓:- 乳腺:3.66 唾液腺:-

IDs

Refseq ID NM_019884
Gene ID 2931
Unigene ID Hs.466828
Probe set ID 632_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105723
GTEx ID ENSG00000105723

オーソログ対応遺伝子

マウス[1]  NM_001031667
ラット[1]  NM_017344

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006987  activation of signaling protein activity involved in unfolded protein response
GO:0003214  cardiac left ventricle morphogenesis
GO:0016477  cell migration
GO:0044267  cellular protein metabolic process
GO:0032869  cellular response to insulin stimulus
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0006349  genetic imprinting
GO:0005977  glycogen metabolic process
GO:0044027  hypermethylation of CpG island
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0046325  negative regulation of glucose import
GO:0045719  negative regulation of glycogen biosynthetic process
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0032007  negative regulation of TOR signaling pathway
GO:0051348  negative regulation of transferase activity
GO:0010905  negative regulation of UDP-glucose catabolic process
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007399  nervous system development
GO:0048015  phosphoinositide-mediated signaling
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0045823  positive regulation of heart contraction
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0045732  positive regulation of protein catabolic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0003073  regulation of systemic arterial blood pressure
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0034236  protein kinase A catalytic subunit binding
GO:0004674  protein serine/threonine kinase activity
GO:0050321  tau-protein kinase activity