huntingtin

詳細情報を見る

同義遺伝子名

Huntington disease protein, HTT, IT15, HD protein, HD, huntingtin (Huntington disease), Huntingtin

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:109 小脳:138.50 脳幹:- 脳梁:58.30 松果体:296.70 末梢神経:- 脊柱:- 網膜:- 目:141 動脈:60 静脈:- リンパ節:131.40 末梢血:36.40 脾臓:37.80 胸腺:51.50 骨髄:39.40 脂肪:- 骨:- 皮膚:57.60
GeneChip 大脳:6.13 小脳:6.31 脳幹:6.12 脳梁:6.01 松果体:- 末梢神経:6.29 脊柱:5.99 網膜:- 目:- 動脈:6.27 静脈:6.31 リンパ節:6.58 末梢血:- 脾臓:6.56 胸腺:6.61 骨髄:6.39 脂肪:6.32 骨:- 皮膚:6.46
CAGE 大脳:4.12 小脳:- 脳幹:3.66 脳梁:3.74 松果体:4.36 末梢神経:- 脊柱:3.69 網膜:- 目:- 動脈:3.79 静脈:3.94 リンパ節:3.68 末梢血:- 脾臓:4.06 胸腺:3.90 骨髄:- 脂肪:3.69 骨:- 皮膚:-
RNA-seq 大脳:2.53 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.65 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.40 骨:- 皮膚:-
EST 子宮:82 胎盤:32.80 前立腺:11.30 卵巣:- 精巣:73.50 心臓:- 骨格筋:20.10 食道:- 胃:85 腸:- 結腸:50.90     肝臓:31.70        肺:176    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:111.50 唾液腺:-
GeneChip 子宮:6.12 胎盤:6.35 前立腺:6.14 卵巣:6.16 精巣:6.40 心臓:5.98 骨格筋:6.36 食道:6.66 胃:6.15 腸:6.48 結腸:6.47 肝臓:6.51 肺:6.52 膀胱:- 腎臓:6.46 下垂体:6.34 甲状腺:6.27 副腎:6.28 膵臓:7.22 乳腺:6.50 唾液腺:5.87
CAGE 子宮:3.69 胎盤:3.40 前立腺:3.49 卵巣:3.47 精巣:3.86 心臓:3.38 骨格筋:3.52 食道:3.67 胃:- 腸:3.69 結腸:4.04     肝臓:3.64    肺:4.21 膀胱:3.32 腎臓:3.45 下垂体:3.66 甲状腺:3.51 副腎:- 膵臓:2.86 乳腺:3.43 唾液腺:3.30
RNA-seq 子宮:- 胎盤:- 前立腺:2.03 卵巣:2.49 精巣:2.41 心臓:1.72 骨格筋:3.44 食道:- 胃:- 腸:- 結腸:1.95     肝臓:1.93        肺:1.99    膀胱:- 腎臓:2.24 下垂体:- 甲状腺:2.39 副腎:2.53 膵臓:- 乳腺:2.38 唾液腺:-

IDs

Refseq ID NM_002111
Gene ID 3064
Unigene ID Hs.518450
Probe set ID 202389_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000197386
GTEx ID ENSG00000197386

オーソログ対応遺伝子

マウス[1]  NM_010414
ラット[2]  NM_024357

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1302016
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0008088  axon cargo transport
GO:0007569  cell aging
GO:0000052  citrulline metabolic process
GO:0008340  determination of adult lifespan
GO:0007212  dopamine receptor signaling pathway
GO:0007029  endoplasmic reticulum organization
GO:0016197  endosome transport
GO:0006888  ER to Golgi vesicle-mediated transport
GO:0000132  establishment of mitotic spindle orientation
GO:0007030  Golgi organization
GO:0042445  hormone metabolic process
GO:0030073  insulin secretion
GO:0055072  iron ion homeostasis
GO:0051938  L-glutamate import
GO:0019244  lactate biosynthetic process from pyruvate
GO:0007626  locomotory behavior
GO:0043524  negative regulation of neuron apoptosis
GO:0021990  neural plate formation
GO:0051402  neuron apoptosis
GO:0048666  neuron development
GO:0021988  olfactory lobe development
GO:0048513  organ development
GO:0048341  paraxial mesoderm formation
GO:0006606  protein import into nucleus
GO:0019805  quinolinate biosynthetic process
GO:0046902  regulation of mitochondrial membrane permeability
GO:0051881  regulation of mitochondrial membrane potential
GO:0046825  regulation of protein export from nucleus
GO:0034047  regulation of protein phosphatase type 2A activity
GO:0048167  regulation of synaptic plasticity
GO:0051592  response to calcium ion
GO:0006890  retrograde vesicle-mediated transport, Golgi to ER
GO:0035176  social behavior
GO:0007283  spermatogenesis
GO:0021756  striatum development
GO:0000050  urea cycle
GO:0047496  vesicle transport along microtubule
GO:0008542  visual learning

Cellular Component

GO:0005776  autophagic vacuole
GO:0030424  axon
GO:0005737  cytoplasm
GO:0030659  cytoplasmic vesicle membrane
GO:0005829  cytosol
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0005794  Golgi apparatus
GO:0016234  inclusion body
GO:0005770  late endosome
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0048487  beta-tubulin binding
GO:0050809  diazepam binding
GO:0034452  dynactin binding
GO:0045505  dynein intermediate chain binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0008134  transcription factor binding