histone deacetylase 2

詳細情報を見る

同義遺伝子名

HD2, YAF1, HDAC2, Histone deacetylase 2, histone deacetylase 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:36.70 小脳:37.80 脳幹:- 脳梁:29.20 松果体:148.30 末梢神経:61.30 脊柱:112.30 網膜:237.30 目:94 動脈:30 静脈:- リンパ節:50.60 末梢血:72.90 脾臓:18.90 胸腺:116 骨髄:275.50 脂肪:- 骨:25.60 皮膚:129.60
GeneChip 大脳:6.74 小脳:6.61 脳幹:6.82 脳梁:6.84 松果体:- 末梢神経:6.79 脊柱:6.63 網膜:- 目:- 動脈:6.84 静脈:6.64 リンパ節:6.89 末梢血:- 脾臓:6.83 胸腺:7.87 骨髄:6.81 脂肪:6.73 骨:- 皮膚:6.94
CAGE 大脳:3.92 小脳:- 脳幹:4.00 脳梁:3.89 松果体:3.96 末梢神経:- 脊柱:4.05 網膜:- 目:- 動脈:3.78 静脈:3.97 リンパ節:4.01 末梢血:- 脾臓:4.03 胸腺:4.58 骨髄:- 脂肪:3.86 骨:- 皮膚:-
RNA-seq 大脳:3.17 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.30 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.34 骨:- 皮膚:-
EST 子宮:145.80 胎盤:25.50 前立腺:45.10 卵巣:- 精巣:199 心臓:25.50 骨格筋:60.30 食道:- 胃:297.40 腸:- 結腸:50.90     肝臓:137.20        肺:83.10    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:163.70 副腎:- 膵臓:124.50 乳腺:102.20 唾液腺:-
GeneChip 子宮:7.51 胎盤:7.33 前立腺:7.33 卵巣:7.50 精巣:7.95 心臓:6.84 骨格筋:6.67 食道:6.92 胃:6.88 腸:6.88 結腸:6.09 肝臓:5.90 肺:6.64 膀胱:- 腎臓:6.56 下垂体:7.29 甲状腺:6.89 副腎:7.06 膵臓:6.91 乳腺:6.73 唾液腺:6.42
CAGE 子宮:4.08 胎盤:4.18 前立腺:4.12 卵巣:4.29 精巣:4.58 心臓:4.08 骨格筋:4.06 食道:4.05 胃:- 腸:3.86 結腸:3.83     肝臓:3.53    肺:4.15 膀胱:4.11 腎臓:4.04 下垂体:4.31 甲状腺:4.11 副腎:- 膵臓:3.84 乳腺:4.76 唾液腺:3.32
RNA-seq 子宮:- 胎盤:- 前立腺:3.85 卵巣:4.35 精巣:4.99 心臓:2.54 骨格筋:2.64 食道:- 胃:- 腸:- 結腸:4.24     肝臓:2.14        肺:3.30    膀胱:- 腎臓:3.62 下垂体:- 甲状腺:3.65 副腎:3.45 膵臓:- 乳腺:3.35 唾液腺:-

IDs

Refseq ID NM_001527
Gene ID 3066
Unigene ID Hs.335239
Probe set ID 201833_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196591
GTEx ID ENSG00000196591

オーソログ対応遺伝子

マウス[1]  NM_008229
ラット[1]  NM_053447

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0055013  cardiac muscle cell development
GO:0006338  chromatin remodeling
GO:0016358  dendrite development
GO:0042733  embryonic digit morphogenesis
GO:0009913  epidermal cell differentiation
GO:0060789  hair follicle placode formation
GO:0021766  hippocampus development
GO:0016575  histone deacetylation
GO:0006344  maintenance of chromatin silencing
GO:0043066  negative regulation of apoptosis
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0045786  negative regulation of cell cycle
GO:0045347  negative regulation of MHC class II biosynthetic process
GO:0010977  negative regulation of neuron projection development
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048011  nerve growth factor receptor signaling pathway
GO:0042475  odontogenesis of dentine-containing tooth
GO:0008284  positive regulation of cell proliferation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0045862  positive regulation of proteolysis
GO:0010870  positive regulation of receptor biosynthetic process
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051896  regulation of protein kinase B signaling cascade
GO:0060297  regulation of sarcomere organization
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0035098  ESC/E(Z) complex
GO:0000792  heterochromatin
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016581  NuRD complex
GO:0005657  replication fork
GO:0016580  Sin3 complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0031490  chromatin DNA binding
GO:0019899  enzyme binding
GO:0004407  histone deacetylase activity
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515  protein binding
GO:0033558  protein deacetylase activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding