major histocompatibility complex, class II, DR beta 4

詳細情報を見る

同義遺伝子名

HLA DRB1, HLA-DR4B, DRB4, HLA-DRB4

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip nodata
CAGE nodata
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST nodata
GeneChip nodata
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:0 卵巣:0 精巣:0 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0 膵臓:- 乳腺:0 唾液腺:-

IDs

Refseq ID NM_021983
Gene ID 3126
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000227357
ENSG00000231021
GTEx ID ENSG00000227357
ENSG00000231021

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019221  cytokine-mediated signaling pathway
GO:0016045  detection of bacterium
GO:0002455  humoral immune response mediated by circulating immunoglobulin
GO:0006955  immune response
GO:0002381  immunoglobulin production during immune response
GO:0002437  inflammatory response to antigenic stimulus
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0002862  negative regulation of inflammatory response to antigenic stimulus
GO:0032689  negative regulation of interferon-gamma production
GO:0042130  negative regulation of T cell proliferation
GO:0051262  protein tetramerization
GO:0032673  regulation of interleukin-4 production
GO:0007165  signal transduction
GO:0031295  T cell costimulation
GO:0050852  T cell receptor signaling pathway
GO:0042088  T-helper 1 type immune response

Cellular Component

GO:0030669  clathrin-coated endocytic vesicle membrane
GO:0030666  endocytic vesicle membrane
GO:0012507  ER to Golgi transport vesicle membrane
GO:0009897  external side of plasma membrane
GO:0000139  Golgi membrane
GO:0005887  integral to plasma membrane
GO:0031902  late endosome membrane
GO:0005765  lysosomal membrane
GO:0042613  MHC class II protein complex
GO:0005886  plasma membrane
GO:0032588  trans-Golgi network membrane
GO:0030658  transport vesicle membrane

Molecular Function

GO:0032395  MHC class II receptor activity
GO:0042605  peptide antigen binding
GO:0005515  protein binding