high-mobility group box 1

詳細情報を見る

同義遺伝子名

High mobility group protein B1, HMG1, HMG-1, HMG3, high-mobility group box 1, High mobility group protein 1, DKFZp686A04236, HMGB1, SBP-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:32 小脳:63 脳幹:- 脳梁:87.50 松果体:- 末梢神経:30.70 脊柱:112.30 網膜:- 目:41.10 動脈:30 静脈:199.90 リンパ節:171.90 末梢血:- 脾臓:75.60 胸腺:51.50 骨髄:157.40 脂肪:161.30 骨:12.80 皮膚:62.40
GeneChip 大脳:9.72 小脳:9.64 脳幹:9.56 脳梁:10.04 松果体:- 末梢神経:9.84 脊柱:9.70 網膜:- 目:- 動脈:9.69 静脈:9.87 リンパ節:10.03 末梢血:- 脾臓:10.02 胸腺:11.13 骨髄:10.19 脂肪:9.66 骨:- 皮膚:9.57
CAGE 大脳:4.83 小脳:- 脳幹:4.88 脳梁:4.78 松果体:5.12 末梢神経:- 脊柱:5.16 網膜:- 目:- 動脈:4.67 静脈:4.45 リンパ節:4.46 末梢血:- 脾臓:4.59 胸腺:4.76 骨髄:- 脂肪:4.43 骨:- 皮膚:-
RNA-seq 大脳:6.18 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:6.07 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.95 骨:- 皮膚:-
EST 子宮:18.20 胎盤:21.90 前立腺:90.10 卵巣:- 精巣:34.60 心臓:76.60 骨格筋:40.20 食道:- 胃:42.50 腸:32.40 結腸:42.40     肝臓:200.60        肺:24.40    膀胱:- 腎臓:41.60 下垂体:347.90 甲状腺:- 副腎:- 膵臓:44.50 乳腺:9.30 唾液腺:-
GeneChip 子宮:10.41 胎盤:8.50 前立腺:9.98 卵巣:10.17 精巣:9.20 心臓:9.48 骨格筋:8.51 食道:9.99 胃:9.97 腸:9.53 結腸:9.69 肝臓:9.77 肺:9.86 膀胱:- 腎臓:9.40 下垂体:8.97 甲状腺:9.76 副腎:9.85 膵臓:8.90 乳腺:9.86 唾液腺:9.22
CAGE 子宮:4.62 胎盤:3.88 前立腺:4.51 卵巣:4.42 精巣:4.04 心臓:4.47 骨格筋:4.50 食道:4.63 胃:- 腸:4.29 結腸:4.42     肝臓:4.08    肺:4.64 膀胱:4.60 腎臓:4.18 下垂体:4.35 甲状腺:4.37 副腎:- 膵臓:4.06 乳腺:4.78 唾液腺:3.85
RNA-seq 子宮:- 胎盤:- 前立腺:6.29 卵巣:6.15 精巣:5.96 心臓:4.86 骨格筋:4.97 食道:- 胃:- 腸:- 結腸:6.41     肝臓:4.94        肺:6.26    膀胱:- 腎臓:5.76 下垂体:- 甲状腺:6.30 副腎:5.90 膵臓:- 乳腺:6.00 唾液腺:-

IDs

Refseq ID NM_002128
Gene ID 3146
Unigene ID Hs.593339
Probe set ID 200679_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000189403
GTEx ID ENSG00000189403

オーソログ対応遺伝子

マウス[10]  NM_010439
ラット[10]  NM_010439

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1909331
2013279
2922262
3697355
8006019
8339930
8366113
8661151
8890171
9036861
9150946
9166431
9472015
9507007
9600082
9628821
9671457
9722660
9812979
9880542
10490593
10531386
10617144
10652254
10962007
11099378
11106654
11246022
11279268
11294645
11299752
11470162
11748221
11748232
12062430
12110890
12149489
12231511
12384917
12456506
12477932
12488489
12517784
12534345
12565837
12591939
12604365
12620891
12665595
12727838
12759333
12785009
12799451
12925773
12935895
14517071
14532127
14534709
14702039
14739282
14999020
15005629
15014079
15130941
15146429
15162419
15201494
15210788
15488733
15489334
15496585
15666359
15733057
15743787
15766246
15793304
15802534
15877951
15915542
15924431
15944249
15994314
16040616
16130169
16169070
16267105
16282196
16570276
16697213
16751357
16802368
16807371
16855214
16916647
16951227
16962095
16966386
16968820
16997859
16997939
17035340
17060403
17142771
17203009
17218606
17346334
17403666
17475879
17502242
17504981
17597834
17610420
17617154
17678959
17895302
17918013
17936030
17958791
17975708
17991152
18029348
18073062
18076993
18160415
18239618
18239742
18250463
18277058
18288272
18294942
18317568
18346273
18354232
18425372
18431589
18441281
18569640
18577209
18599803
18631454
18644848
18655026
18670905
18680137
18682735
18692049
18707018
18715162
18720262
18759291
18768881
18788635
18799030
18822317
18825489
18825712
18846108
18850631
18854154
18949384
18952078
18974890
18984601
18996119
19005067
19009026
19044016
19087540
19139725
19148477
19150066
19151394
19158276
19197071
19201506
19214652
19223331
19247800
19387923
19398086
19417608
19445369
19446504
19451748
19471022
19476625
19505873
19515846
19530996
19533845
19545550
19564572
19571604
19572890
19616266
19639200
19666121
19679874
19726280
19738201
19751520
19777384
19786934
19800306
19811284
19819342
19837864
19841752
19876719
19887013
19930620
19933377
19948257
19962765
20007974
20044610
20110525
20123074
20123075
20123076
20185963
20193282
20195357
20200191
20207250
20231695
20302902
20350435
20360068
20414834
20419158
20430742
20510002
20579387
20622903
20659154
20723409
20799933
20812762
20826760
20844833
20846416
20927132
20936104
20959471
20980161
21042739
21044333
21044950
21052685
21092200
21093407
21099216
21116278
21120500
21139048
21146549
21151833
21163940
21181308
21198433
21211520
21241404
21283827
21303685
21319273
21365018
21366949
21380479
21395369
21435605
21442152
21443191
21457762
21457800
21520052
21532866
21548924
21617575
21617715
21642542
21650061
21656024
21691146
21743489
21752923
21788990
21825870
21860212
21864037
21871094
21890473
21900206
21906983
21914366
21915243
21926646
21940680
21944254
21944908
21947243
21953322
21957148
21958433
21963094
21968272
21989210
21990362
22012330
22020142
22025513
22047946
22102692
22105604
22108005
22110531
22127462
22127490
22189477
22189943
22231645
22237993
22248244
22265157
22275109
22293756
22306257
22331597
22333024
22345153
22348591
22361176
22369934
22370717
22379092
22391561
22394598
22473704
22484401
22496788
22505724
22521432
22544356
22549180
22549347
22552293
22578261
22609241
22623428
22644337
22672360
22696656
22703527
22747650
22750245
22780932
22782142
22842346
22862965
22883976
22884669
22909167
22922889
22928592
22931605
22932142
22939629
22960399
22983919
23000965
23023232
23042506
23055574
23063560
23070967
23118492
23122444
23143556
23157129
23175347
23194089
23204053
23207101
23213216
23228930
23231044
23244202
23255728
23260004
23269659
23269975
23284878
23288170
23317219
23318458
23325855
23328212
23336955
23339448
23359306
23384711
23403315
23414695
23440398
23447529
23467607
23485600
23549344
23602568
23616573
23628898
23649808
23685846
23691208
23708738
23711070
23723299
23727604
23729200
23836405
23858044
23866030
23883808
23911608
23928875
23938155
23948596
23954397
23964150
23974442
24012904
24078503
24082908
24133029
24146279
24152844
24160326
24188108
24200063
24257755
24302768
24302816
24337577
24420129
24464016
24567328
24579204
24654937
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0006288  base-excision repair, DNA ligation
GO:0006921  cell structure disassembly during apoptosis
GO:0002407  dendritic cell chemotaxis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0051103  DNA ligation during DNA repair
GO:0006310  DNA recombination
GO:0006265  DNA topological change
GO:0002437  inflammatory response to antigenic stimulus
GO:0045087  innate immune response
GO:0001773  myeloid dendritic cell activation
GO:0017055  negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0031175  neuron projection development
GO:0050918  positive chemotaxis
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0043388  positive regulation of DNA binding
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0033151  V(D)J recombination

Cellular Component

GO:0009986  cell surface
GO:0000793  condensed chromosome
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0003684  damaged DNA binding
GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0005515  protein binding
GO:0050786  RAGE receptor binding
GO:0003697  single-stranded DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding