heme oxygenase (decycling) 1

詳細情報を見る

同義遺伝子名

heme oxygenase (decycling) 1, HO, HO-1, HMOX1, bK286B10, Heme oxygenase 1, heme oxygenase-1, heme oxygenase-1 (HO-1), HO1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:13 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:76.40 動脈:119.90 静脈:133.30 リンパ節:- 末梢血:510.10 脾臓:434.80 胸腺:25.80 骨髄:19.70 脂肪:40.30 骨:51.20 皮膚:24
GeneChip 大脳:5.62 小脳:5.06 脳幹:5.83 脳梁:6.10 松果体:- 末梢神経:6.03 脊柱:6.53 網膜:- 目:- 動脈:6.46 静脈:6.18 リンパ節:6.94 末梢血:- 脾臓:8.14 胸腺:5.78 骨髄:7.80 脂肪:6.82 骨:- 皮膚:7.30
CAGE 大脳:2.94 小脳:- 脳幹:3.48 脳梁:3.57 松果体:2.59 末梢神経:- 脊柱:4.12 網膜:- 目:- 動脈:4.54 静脈:4.46 リンパ節:4.94 末梢血:- 脾臓:7.04 胸腺:2.90 骨髄:- 脂肪:4.82 骨:- 皮膚:-
RNA-seq 大脳:2.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:5.92 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.77 骨:- 皮膚:-
EST 子宮:- 胎盤:346.10 前立腺:- 卵巣:111.80 精巣:13 心臓:25.50 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:33.90     肝臓:31.70        肺:68.40    膀胱:- 腎臓:52 下垂体:- 甲状腺:- 副腎:101.60 膵臓:17.80 乳腺:27.90 唾液腺:-
GeneChip 子宮:5.78 胎盤:7.79 前立腺:5.21 卵巣:6.60 精巣:6.06 心臓:6.25 骨格筋:5.83 食道:7.10 胃:5.55 腸:6.59 結腸:6.20 肝臓:7.03 肺:6.78 膀胱:- 腎臓:6.92 下垂体:5.31 甲状腺:5.33 副腎:5.92 膵臓:6.20 乳腺:6.01 唾液腺:5.39
CAGE 子宮:2.79 胎盤:4.69 前立腺:3.13 卵巣:4.98 精巣:3.74 心臓:3.78 骨格筋:3.76 食道:3.81 胃:- 腸:4.82 結腸:3.89     肝臓:5.70    肺:5.10 膀胱:3.68 腎臓:4.82 下垂体:2.24 甲状腺:3.14 副腎:- 膵臓:2.54 乳腺:4.44 唾液腺:2.31
RNA-seq 子宮:- 胎盤:- 前立腺:3.27 卵巣:5.93 精巣:3.39 心臓:1.83 骨格筋:3.89 食道:- 胃:- 腸:- 結腸:2.58     肝臓:6.62        肺:5.62    膀胱:- 腎臓:5.36 下垂体:- 甲状腺:4.05 副腎:5.45 膵臓:- 乳腺:4.09 唾液腺:-

IDs

Refseq ID NM_002133
Gene ID 3162
Unigene ID Hs.517581
Probe set ID 203665_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100292
GTEx ID ENSG00000100292

オーソログ対応遺伝子

マウス[1]  NM_010442
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0008219  cell death
GO:0006879  cellular iron ion homeostasis
GO:0071276  cellular response to cadmium ion
GO:0071456  cellular response to hypoxia
GO:0031670  cellular response to nutrient
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0001935  endothelial cell proliferation
GO:0034101  erythrocyte homeostasis
GO:0007588  excretion
GO:0002246  healing during inflammatory response
GO:0042167  heme catabolic process
GO:0006788  heme oxidation
GO:0055072  iron ion homeostasis
GO:0034383  low-density lipoprotein particle clearance
GO:0043392  negative regulation of DNA binding
GO:0002686  negative regulation of leukocyte migration
GO:0032764  negative regulation of mast cell cytokine production
GO:0043305  negative regulation of mast cell degranulation
GO:0043524  negative regulation of neuron apoptosis
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0043433  negative regulation of transcription factor activity
GO:0006778  porphyrin metabolic process
GO:0045766  positive regulation of angiogenesis
GO:0045080  positive regulation of chemokine biosynthetic process
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045909  positive regulation of vasodilation
GO:0051260  protein homooligomerization
GO:0007243  protein kinase cascade
GO:0045765  regulation of angiogenesis
GO:0008217  regulation of blood pressure
GO:0051090  regulation of transcription factor activity
GO:0043619  regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627  response to estrogen stimulus
GO:0042542  response to hydrogen peroxide
GO:0035094  response to nicotine
GO:0006979  response to oxidative stress
GO:0007264  small GTPase mediated signal transduction
GO:0014806  smooth muscle hyperplasia
GO:0055085  transmembrane transport

Cellular Component

GO:0005901  caveola
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005615  extracellular space
GO:0016020  membrane
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0019899  enzyme binding
GO:0020037  heme binding
GO:0004392  heme oxygenase (decyclizing) activity
GO:0046872  metal ion binding
GO:0004630  phospholipase D activity
GO:0042803  protein homodimerization activity
GO:0004871  signal transducer activity