heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

詳細情報を見る

同義遺伝子名

Immunoglobulin heavy chain-binding protein, GRP78, BIP, HSPA5, 78 kDa glucose-regulated protein precursor, FLJ26106, Heat shock 70 kDa protein 5, GRP 78, MIF2, BiP

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:8.69 小脳:8.17 脳幹:8.72 脳梁:8.98 松果体:- 末梢神経:9.52 脊柱:9.74 網膜:- 目:- 動脈:9.75 静脈:10.84 リンパ節:9.42 末梢血:- 脾臓:9.06 胸腺:9.46 骨髄:9.43 脂肪:9.51 骨:- 皮膚:9.21
CAGE 大脳:4.98 小脳:- 脳幹:5.46 脳梁:5.14 松果体:5.25 末梢神経:- 脊柱:4.99 網膜:- 目:- 動脈:5.85 静脈:5.36 リンパ節:5.53 末梢血:- 脾臓:5.61 胸腺:5.07 骨髄:- 脂肪:5.70 骨:- 皮膚:-
RNA-seq 大脳:5.33 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:7.72 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:6.01 骨:- 皮膚:-
EST nodata
GeneChip 子宮:9.79 胎盤:10.28 前立腺:10.28 卵巣:10.07 精巣:10.12 心臓:9.97 骨格筋:8.13 食道:9.61 胃:10 腸:9.85 結腸:9.25 肝臓:9.78 肺:9.85 膀胱:- 腎臓:9.40 下垂体:10.25 甲状腺:10.85 副腎:9.53 膵臓:10.73 乳腺:9.25 唾液腺:9.84
CAGE 子宮:5.34 胎盤:6.16 前立腺:5.44 卵巣:5.69 精巣:5.70 心臓:5.96 骨格筋:5.18 食道:5.45 胃:- 腸:5.72 結腸:5.02     肝臓:6.92    肺:5.71 膀胱:6.02 腎臓:6.17 下垂体:5.97 甲状腺:7.42 副腎:- 膵臓:6.71 乳腺:6.23 唾液腺:5.96
RNA-seq 子宮:- 胎盤:- 前立腺:6.37 卵巣:7.16 精巣:7.28 心臓:5.75 骨格筋:5.23 食道:- 胃:- 腸:- 結腸:7.89     肝臓:8.00        肺:8.25    膀胱:- 腎臓:8.32 下垂体:- 甲状腺:6.24 副腎:6.82 膵臓:- 乳腺:6.15 唾液腺:-

IDs

Refseq ID NM_005347
Gene ID 3309
Unigene ID -
Probe set ID 211936_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000044574
GTEx ID ENSG00000044574

オーソログ対応遺伝子

マウス[8]  NM_001163434, NM_022310
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1480470
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006987  activation of signaling protein activity involved in unfolded protein response
GO:0006200  ATP catabolic process
GO:0007596  blood coagulation
GO:0044267  cellular protein metabolic process
GO:0042149  cellular response to glucose starvation
GO:0071353  cellular response to interleukin-4
GO:0021680  cerebellar Purkinje cell layer development
GO:0021589  cerebellum structural organization
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0006983  ER overload response
GO:0030433  ER-associated protein catabolic process
GO:0043066  negative regulation of apoptosis
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0031398  positive regulation of protein ubiquitination
GO:0060904  regulation of protein folding in endoplasmic reticulum

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0034663  endoplasmic reticulum chaperone complex
GO:0005788  endoplasmic reticulum lumen
GO:0005789  endoplasmic reticulum membrane
GO:0005793  ER-Golgi intermediate compartment
GO:0030176  integral to endoplasmic reticulum membrane
GO:0042470  melanosome
GO:0030496  midbody
GO:0005634  nucleus
GO:0008180  signalosome

Molecular Function

GO:0005524  ATP binding
GO:0016887  ATPase activity
GO:0005509  calcium ion binding
GO:0051087  chaperone binding
GO:0051787  misfolded protein binding
GO:0005515  protein binding
GO:0030674  protein binding, bridging
GO:0019904  protein domain specific binding
GO:0043022  ribosome binding
GO:0031625  ubiquitin protein ligase binding
GO:0051082  unfolded protein binding