interleukin 2

 詳細情報を見る

同義遺伝子名

interleukin 2, Interleukin-2 precursor, lymphokine, T-cell growth factor, Aldesleukin, TCGF, IL-2, IL2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:2.77 小脳:2.70 脳幹:2.82 脳梁:2.80 松果体:- 末梢神経:2.74 脊柱:2.69 網膜:- 目:- 動脈:2.74 静脈:2.89 リンパ節:2.88 末梢血:- 脾臓:2.75 胸腺:2.63 骨髄:2.80 脂肪:2.80 骨:- 皮膚:2.85
CAGE nodata
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.75 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:2.76 胎盤:2.75 前立腺:2.69 卵巣:2.78 精巣:2.60 心臓:2.81 骨格筋:2.92 食道:2.71 胃:2.72 腸:2.82 結腸:2.86 肝臓:2.74 肺:2.76 膀胱:- 腎臓:2.74 下垂体:2.65 甲状腺:2.64 副腎:2.69 膵臓:2.85 乳腺:2.72 唾液腺:2.73
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:0 卵巣:0 精巣:0 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.02     肝臓:0        肺:0.06    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0.24 膵臓:- 乳腺:0 唾液腺:-

詳細情報

IDs

Refseq ID NM_000586
Gene ID 3558
Unigene ID Hs.89679
Probe set ID 207849_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000109471
GTEx ID ENSG00000109471

オーソログ対応遺伝子

マウス[1]  NM_008366
ラット [0]  

染色体

4q27  [123,372,625  -  123,377,880]

遺伝子ファミリー (Interpro ID)

IPR009079  Four-helical cytokine-like, core
IPR000779  Interleukin-2

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0007155  cell adhesion
GO:0007267  cell-cell signaling
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0006955  immune response
GO:0030101  natural killer cell activation
GO:0043066  negative regulation of apoptosis
GO:0002903  negative regulation of B cell apoptosis
GO:0045822  negative regulation of heart contraction
GO:0050728  negative regulation of inflammatory response
GO:0050672  negative regulation of lymphocyte proliferation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0042104  positive regulation of activated T cell proliferation
GO:0030890  positive regulation of B cell proliferation
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0051024  positive regulation of immunoglobulin secretion
GO:0050729  positive regulation of inflammatory response
GO:0032729  positive regulation of interferon-gamma production
GO:0032740  positive regulation of interleukin-17 production
GO:0048304  positive regulation of isotype switching to IgG isotypes
GO:0045591  positive regulation of regulatory T cell differentiation
GO:0034105  positive regulation of tissue remodeling
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046013  regulation of T cell homeostatic proliferation
GO:0030217  T cell differentiation

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0030246  carbohydrate binding
GO:0005125  cytokine activity
GO:0043208  glycosphingolipid binding
GO:0008083  growth factor activity
GO:0005134  interleukin-2 receptor binding
GO:0031851  kappa-type opioid receptor binding
GO:0019209  kinase activator activity