Fas ligand (TNF superfamily, member 6)

詳細情報を見る

同義遺伝子名

FASL, Fas antigen ligand, Apoptosis antigen ligand, CD178 antigen, CD178, FasL, Fas ligand (TNF superfamily, member 6), APTL, Fas ligand, FASLG, CD95L protein, CD95L, Tumor necrosis factor ligand superfamily member 6, TNFSF6, APT1LG1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:54.50 小脳:63 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:112.30 網膜:118.60 目:76.40 動脈:30 静脈:- リンパ節:80.90 末梢血:36.40 脾臓:113.40 胸腺:25.80 骨髄:275.50 脂肪:80.70 骨:64 皮膚:67.20
GeneChip 大脳:4.45 小脳:4.48 脳幹:4.38 脳梁:4.30 松果体:- 末梢神経:4.08 脊柱:4.20 網膜:- 目:- 動脈:4.44 静脈:4.46 リンパ節:4.47 末梢血:- 脾臓:4.96 胸腺:4.16 骨髄:4.42 脂肪:4.46 骨:- 皮膚:4.28
CAGE 大脳:0.02 小脳:- 脳幹:0.07 脳梁:0.07 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.34 静脈:0.34 リンパ節:0.63 末梢血:- 脾臓:1.09 胸腺:0.23 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.66 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:9.10 胎盤:40.10 前立腺:45.10 卵巣:186.30 精巣:13 心臓:12.80 骨格筋:20.10 食道:- 胃:318.60 腸:64.80 結腸:220.50     肝臓:31.70        肺:73.30    膀胱:125.60 腎臓:10.40 下垂体:116 甲状腺:- 副腎:- 膵臓:80 乳腺:83.60 唾液腺:-
GeneChip 子宮:4.29 胎盤:4.11 前立腺:4.03 卵巣:4.32 精巣:4.17 心臓:4.59 骨格筋:4.64 食道:4.34 胃:4.53 腸:4.39 結腸:4.77 肝臓:4.66 肺:4.29 膀胱:- 腎臓:4.33 下垂体:4.45 甲状腺:4.12 副腎:4.50 膵臓:4.50 乳腺:4.11 唾液腺:4.69
CAGE 子宮:0.44 胎盤:0.48 前立腺:0.33 卵巣:0.20 精巣:0.04 心臓:0.12 骨格筋:0.05 食道:0.09 胃:- 腸:0.61 結腸:0.27     肝臓:0.26    肺:0.94 膀胱:0.09 腎臓:0.15 下垂体:0 甲状腺:0.06 副腎:- 膵臓:0 乳腺:0 唾液腺:0.36
RNA-seq 子宮:- 胎盤:- 前立腺:0.05 卵巣:0.22 精巣:0.12 心臓:0.03 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0.08        肺:0.84    膀胱:- 腎臓:0.08 下垂体:- 甲状腺:0 副腎:0.79 膵臓:- 乳腺:0.15 唾液腺:-

IDs

Refseq ID NM_000639
Gene ID 356
Unigene ID Hs.200716
Probe set ID 210865_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000117560
GTEx ID ENSG00000117560

オーソログ対応遺伝子

マウス[2]  NM_001205243, NM_010177
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006915  apoptosis
GO:0007267  cell-cell signaling
GO:0030644  cellular chloride ion homeostasis
GO:0033554  cellular response to stress
GO:0048388  endosomal lumen acidification
GO:0006955  immune response
GO:0006917  induction of apoptosis
GO:0008625  induction of apoptosis via death domain receptors
GO:0060555  induction of necroptosis by extracellular signals
GO:0060554  induction of necroptosis of activated-T cells
GO:0006925  inflammatory cell apoptosis
GO:0070265  necrotic cell death
GO:0016525  negative regulation of angiogenesis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0045742  positive regulation of epidermal growth factor receptor signaling pathway
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043525  positive regulation of neuron apoptosis
GO:0070848  response to growth factor stimulus
GO:0032496  response to lipopolysaccharide
GO:0046666  retinal cell programmed cell death
GO:0007165  signal transduction
GO:0070231  T cell apoptosis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005901  caveola
GO:0060205  cytoplasmic membrane-bounded vesicle lumen
GO:0009897  external side of plasma membrane
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0070062  extracellular vesicular exosome
GO:0005887  integral to plasma membrane
GO:0043202  lysosomal lumen
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm

Molecular Function

GO:0005125  cytokine activity
GO:0005515  protein binding
GO:0005102  receptor binding
GO:0005164  tumor necrosis factor receptor binding