integrin-linked kinase

同義遺伝子名

p59ILK, Integrin-linked protein kinase 1, ILK1, 59 kDa serine/threonine-protein kinase, integrin-linked kinase, P59, ILK-1, ILK, DKFZp686F1765

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:7.92

小脳:7.88

脳幹:7.94

脳梁:8.08

松果体:-

末梢神経:8.68

脊柱:8.13

網膜:-

目:-

動脈:9.86

静脈:9.83

リンパ節:8.33

末梢血:-

脾臓:8.57

胸腺:7.80

骨髄:8.51

脂肪:8.96

骨:-

皮膚:8.49

CAGE

大脳:3.23

小脳:-

脳幹:3.19

脳梁:3.41

松果体:3.42

末梢神経:-

脊柱:3.25

網膜:-

目:-

動脈:5.25

静脈:3.77

リンパ節:3.44

末梢血:-

脾臓:3.64

胸腺:2.67

骨髄:-

脂肪:3.64

骨:-

皮膚:-

RNA-seq

大脳:2.74

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.67

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.02

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:9.63

胎盤:8.43

前立腺:9.06

卵巣:8.97

精巣:8.10

心臓:9.01

骨格筋:8.26

食道:8.58

胃:9.03

腸:8.87

結腸:9.10

肝臓:7.94

肺:8.94

膀胱:-

腎臓:8.61

下垂体:8.29

甲状腺:8.41

副腎:8.55

膵臓:8.15

乳腺:9.08

唾液腺:8.42

CAGE

子宮:4.77

胎盤:3.74

前立腺:4.41

卵巣:3.92

精巣:3.43

心臓:4.28

骨格筋:3.54

食道:4.30

胃:-

腸:3.62

結腸:4.54

肝臓:3.22

肺:3.96

膀胱:4.82

腎臓:3.75

下垂体:3.08

甲状腺:3.52

副腎:-

膵臓:3.71

乳腺:4.37

唾液腺:3.82

RNA-seq

子宮:-

胎盤:-

前立腺:5.00

卵巣:3.18

精巣:3.16

心臓:3.26

骨格筋:3.29

食道:-

胃:-

腸:-

結腸:4.22

肝臓:1.82

肺:4.34

膀胱:-

腎臓:3.12

下垂体:-

甲状腺:2.42

副腎:3.18

膵臓:-

乳腺:2.91

唾液腺:-

IDs

Refseq ID	NM_004517
Gene ID	3611
Unigene ID	-
Probe set ID	201234_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000166333
GTEx ID	ENSG00000166333

オーソログ対応遺伝子

マウス[2]	NM_001161724, NM_010562
ラット[1]	NM_133409, NM_010562

染色体

11p15.4 [6,624,961 - 6,632,102]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001658	branching involved in ureteric bud morphogenesis
GO:0007569	cell aging
GO:0007050	cell cycle arrest
GO:0034329	cell junction assembly
GO:0008283	cell proliferation
GO:0007160	cell-matrix adhesion
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
GO:0043206	fibril organization
GO:0007229	integrin-mediated signaling pathway
GO:0032288	myelin assembly
GO:0022011	myelination in the peripheral nervous system
GO:0010667	negative regulation of cardiac muscle cell apoptosis
GO:0043524	negative regulation of neuron apoptosis
GO:0006469	negative regulation of protein kinase activity
GO:0014912	negative regulation of smooth muscle cell migration
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0021675	nerve development
GO:0048812	neuron projection morphogenesis
GO:0018105	peptidyl-serine phosphorylation
GO:0045773	positive regulation of axon extension
GO:0030513	positive regulation of BMP signaling pathway
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0001954	positive regulation of cell-matrix adhesion
GO:0050775	positive regulation of dendrite morphogenesis
GO:0043406	positive regulation of MAP kinase activity
GO:0045663	positive regulation of myoblast differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0042327	positive regulation of phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0043491	protein kinase B signaling cascade
GO:0032956	regulation of actin cytoskeleton organization
GO:0034446	substrate adhesion-dependent cell spreading

Cellular Component

GO:0043025	cell soma
GO:0005911	cell-cell junction
GO:0043034	costamere
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043198	dendritic shaft
GO:0005925	focal adhesion
GO:0030027	lamellipodium
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0030017	sarcomere
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity
GO:0017124	SH3 domain binding
GO:0004871	signal transducer activity

integrin-linked kinase

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function