insulin

 詳細情報を見る

同義遺伝子名

Insulin precursor, INS, insulin

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:4.19 小脳:4.17 脳幹:4.23 脳梁:4.07 松果体:- 末梢神経:3.91 脊柱:3.91 網膜:- 目:- 動脈:4.12 静脈:4.08 リンパ節:4.19 末梢血:- 脾臓:4.20 胸腺:3.84 骨髄:4.20 脂肪:4.20 骨:- 皮膚:4.33
CAGE nodata
RNA-seq 大脳:0.10 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:3.94 胎盤:3.96 前立腺:3.72 卵巣:4.06 精巣:4.01 心臓:4.54 骨格筋:4.51 食道:4.15 胃:4.07 腸:7.57 結腸:4.26 肝臓:4.04 肺:3.99 膀胱:- 腎臓:4.10 下垂体:4.02 甲状腺:3.99 副腎:4.50 膵臓:12.80 乳腺:3.95 唾液腺:4.26
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:0.10 卵巣:0 精巣:0 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0 膵臓:- 乳腺:0 唾液腺:-

詳細情報

IDs

Refseq ID NM_000207
Gene ID 3630
Unigene ID -
Probe set ID 206598_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000254647
GTEx ID ENSG00000254647

オーソログ対応遺伝子

マウス[2]  NM_001185083, NM_001185084, NM_008387, NM_008386
ラット[1]  NM_019129, NM_019130, NM_008387, NM_008386

染色体

11p15.5  [2,181,009  -  2,182,571]

遺伝子ファミリー (Interpro ID)

IPR016179  Insulin-like
IPR004825  Insulin/IGF/relaxin

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0032148  activation of protein kinase B activity
GO:0006953  acute-phase response
GO:0046631  alpha-beta T cell activation
GO:0007267  cell-cell signaling
GO:0044267  cellular protein metabolic process
GO:0031018  endocrine pancreas development
GO:0006112  energy reserve metabolic process
GO:0055089  fatty acid homeostasis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0042593  glucose homeostasis
GO:0006006  glucose metabolic process
GO:0015758  glucose transport
GO:0008286  insulin receptor signaling pathway
GO:0000165  MAPKKK cascade
GO:0002674  negative regulation of acute inflammatory response
GO:0045922  negative regulation of fatty acid metabolic process
GO:0045721  negative regulation of gluconeogenesis
GO:0045818  negative regulation of glycogen catabolic process
GO:0050995  negative regulation of lipid catabolic process
GO:0033861  negative regulation of NAD(P)H oxidase activity
GO:0042177  negative regulation of protein catabolic process
GO:0032460  negative regulation of protein oligomerization
GO:0050709  negative regulation of protein secretion
GO:0045861  negative regulation of proteolysis
GO:0060266  negative regulation of respiratory burst during acute inflammatory response
GO:0045908  negative regulation of vasodilation
GO:0045597  positive regulation of cell differentiation
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0032270  positive regulation of cellular protein metabolic process
GO:0050715  positive regulation of cytokine secretion
GO:0045740  positive regulation of DNA replication
GO:0046326  positive regulation of glucose import
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0045821  positive regulation of glycolysis
GO:0046628  positive regulation of insulin receptor signaling pathway
GO:0046889  positive regulation of lipid biosynthetic process
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0051000  positive regulation of nitric-oxide synthase activity
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0060267  positive regulation of respiratory burst
GO:0045909  positive regulation of vasodilation
GO:0006521  regulation of cellular amino acid metabolic process
GO:0050796  regulation of insulin secretion
GO:0032880  regulation of protein localization
GO:0050708  regulation of protein secretion
GO:0006355  regulation of transcription, DNA-dependent
GO:0022898  regulation of transmembrane transporter activity
GO:0042060  wound healing

Cellular Component

GO:0005788  endoplasmic reticulum lumen
GO:0031904  endosome lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen
GO:0034774  secretory granule lumen

Molecular Function

GO:0005179  hormone activity
GO:0005158  insulin receptor binding
GO:0005159  insulin-like growth factor receptor binding
GO:0002020  protease binding
GO:0005515  protein binding