insulin receptor

詳細情報を見る

同義遺伝子名

INSR, CD220, Insulin receptor precursor, CD220 antigen, HHF5, insulin receptor, IR

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:35.30

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:12.90

骨髄:-

脂肪:40.30

骨:-

皮膚:-

GeneChip

大脳:6.93

小脳:7.05

脳幹:6.86

脳梁:7.65

松果体:-

末梢神経:7.43

脊柱:7.29

網膜:-

目:-

動脈:8.37

静脈:7.32

リンパ節:6.96

末梢血:-

脾臓:9.19

胸腺:6.46

骨髄:6.96

脂肪:7.32

骨:-

皮膚:6.94

CAGE

大脳:3.42

小脳:-

脳幹:3.81

脳梁:4.03

松果体:2.46

末梢神経:-

脊柱:3.28

網膜:-

目:-

動脈:4.23

静脈:3.39

リンパ節:2.74

末梢血:-

脾臓:5.29

胸腺:2.43

骨髄:-

脂肪:4.15

骨:-

皮膚:-

RNA-seq

大脳:0.00

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.05

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.94

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:9.10

胎盤:-

前立腺:22.50

卵巣:37.30

精巣:17.30

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:10.60

肺:24.40

膀胱:-

腎臓:52

下垂体:-

甲状腺:-

副腎:50.80

膵臓:53.30

乳腺:-

唾液腺:-

GeneChip

子宮:7.46

胎盤:7.76

前立腺:7.99

卵巣:7.79

精巣:6.66

心臓:7.66

骨格筋:7.86

食道:6.92

胃:7.74

腸:7.45

結腸:7.22

肝臓:8.93

肺:7.26

膀胱:-

腎臓:8.66

下垂体:7.80

甲状腺:8.06

副腎:8.82

膵臓:8.06

乳腺:7.63

唾液腺:8.34

CAGE

子宮:4.18

胎盤:4.66

前立腺:3.96

卵巣:4.63

精巣:3.43

心臓:4.02

骨格筋:3.88

食道:3.22

胃:-

腸:4.28

結腸:3.91

肝臓:4.80

肺:3.21

膀胱:3.97

腎臓:3.94

下垂体:3.88

甲状腺:4.29

副腎:-

膵臓:5.62

乳腺:4.00

唾液腺:4.16

RNA-seq

子宮:-

胎盤:-

前立腺:3.69

卵巣:2.85

精巣:3.51

心臓:3.45

骨格筋:5.15

食道:-

胃:-

腸:-

結腸:3.21

肝臓:3.55

肺:1.90

膀胱:-

腎臓:2.27

下垂体:-

甲状腺:3.03

副腎:2.79

膵臓:-

乳腺:3.48

唾液腺:-

IDs

Refseq ID	NM_000208
Gene ID	3643
Unigene ID	Hs.465744
Probe set ID	213792_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000171105
GTEx ID	ENSG00000171105

オーソログ対応遺伝子

マウス[2]	NM_010568
ラット [0]

染色体

19p13.2 [7,112,266 - 7,294,011]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0005975	carbohydrate metabolic process
GO:0071363	cellular response to growth factor stimulus
GO:0032869	cellular response to insulin stimulus
GO:0031017	exocrine pancreas development
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042593	glucose homeostasis
GO:0003007	heart morphogenesis
GO:0008286	insulin receptor signaling pathway
GO:0030238	male sex determination
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0048639	positive regulation of developmental growth
GO:0045740	positive regulation of DNA replication
GO:0046326	positive regulation of glucose import
GO:0045725	positive regulation of glycogen biosynthetic process
GO:0045821	positive regulation of glycolysis
GO:0043410	positive regulation of MAPKKK cascade
GO:0045840	positive regulation of mitosis
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0060267	positive regulation of respiratory burst
GO:0046777	protein amino acid autophosphorylation
GO:0051290	protein heterotetramerization
GO:0045995	regulation of embryonic development
GO:0006355	regulation of transcription, DNA-dependent
GO:0019087	transformation of host cell by virus

Cellular Component

GO:0005901	caveola
GO:0010008	endosome membrane
GO:0005899	insulin receptor complex
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0043559	insulin binding
GO:0005009	insulin receptor activity
GO:0043560	insulin receptor substrate binding
GO:0031994	insulin-like growth factor I binding
GO:0031995	insulin-like growth factor II binding
GO:0005159	insulin-like growth factor receptor binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0004713	protein tyrosine kinase activity
GO:0051425	PTB domain binding
GO:0004716	receptor signaling protein tyrosine kinase activity
GO:0042169	SH2 domain binding

insulin receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function