integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

詳細情報を見る

同義遺伝子名

Vitronectin receptor subunit alpha, antigen identified by monoclonal antibody L230, ITGAV, VNRA, CD51, MSK8, CD51 antigen, Integrin alpha-V precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:58.10 小脳:25.20 脳幹:- 脳梁:116.60 松果体:- 末梢神経:61.30 脊柱:112.30 網膜:355.90 目:111.70 動脈:119.90 静脈:- リンパ節:20.20 末梢血:18.20 脾臓:- 胸腺:64.40 骨髄:19.70 脂肪:40.30 骨:153.50 皮膚:96
GeneChip 大脳:8.34 小脳:8 脳幹:8.65 脳梁:8.84 松果体:- 末梢神経:9.20 脊柱:9.37 網膜:- 目:- 動脈:8.97 静脈:8.55 リンパ節:7.81 末梢血:- 脾臓:7.57 胸腺:7.99 骨髄:5.18 脂肪:8.22 骨:- 皮膚:8.53
CAGE 大脳:4.26 小脳:- 脳幹:4.55 脳梁:4.56 松果体:4.16 末梢神経:- 脊柱:4.78 網膜:- 目:- 動脈:4.85 静脈:3.78 リンパ節:3.41 末梢血:- 脾臓:3.91 胸腺:3.35 骨髄:- 脂肪:4.57 骨:- 皮膚:-
RNA-seq 大脳:1.34 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.47 骨:- 皮膚:-
EST 子宮:127.60 胎盤:105.60 前立腺:56.30 卵巣:37.30 精巣:38.90 心臓:89.40 骨格筋:60.30 食道:- 胃:21.20 腸:97.20 結腸:33.90     肝臓:63.30        肺:112.40    膀胱:- 腎臓:104 下垂体:- 甲状腺:- 副腎:50.80 膵臓:133.40 乳腺:148.70 唾液腺:-
GeneChip 子宮:9.32 胎盤:9.15 前立腺:9.05 卵巣:9.20 精巣:7.34 心臓:8.83 骨格筋:7.54 食道:7.26 胃:8.12 腸:8.06 結腸:6.25 肝臓:6.57 肺:8.13 膀胱:- 腎臓:8.27 下垂体:7.60 甲状腺:8.91 副腎:8.60 膵臓:6.95 乳腺:8.22 唾液腺:8.26
CAGE 子宮:4.63 胎盤:4.69 前立腺:4.18 卵巣:4.42 精巣:3.89 心臓:4.64 骨格筋:3.45 食道:4.05 胃:- 腸:3.69 結腸:3.83     肝臓:3.49    肺:4.17 膀胱:4.19 腎臓:5.27 下垂体:3.92 甲状腺:4.49 副腎:- 膵臓:4.20 乳腺:4.66 唾液腺:4.39
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:1.09 精巣:0.97 心臓:2.03 骨格筋:1.91 食道:- 胃:- 腸:- 結腸:0.98     肝臓:0.00        肺:0.31    膀胱:- 腎臓:1.42 下垂体:- 甲状腺:2.04 副腎:0.00 膵臓:- 乳腺:1.76 唾液腺:-

IDs

Refseq ID NM_002210
Gene ID 3685
Unigene ID Hs.436873
Probe set ID 202351_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138448
GTEx ID ENSG00000138448

オーソログ対応遺伝子

マウス[3]  NM_008402
ラット[3]  NM_008402

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1532572
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0043277  apoptotic cell clearance
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0070588  calcium ion transmembrane transport
GO:0007155  cell adhesion
GO:0007160  cell-matrix adhesion
GO:0052066  entry of symbiont into host cell by promotion of host phagocytosis
GO:0046718  entry of virus into host cell
GO:0070371  ERK1 and ERK2 cascade
GO:0030198  extracellular matrix organization
GO:0007229  integrin-mediated signaling pathway
GO:0050900  leukocyte migration
GO:0043066  negative regulation of apoptosis
GO:0010888  negative regulation of lipid storage
GO:0032369  negative regulation of lipid transport
GO:0050748  negative regulation of lipoprotein metabolic process
GO:0045715  negative regulation of low-density lipoprotein receptor biosynthetic process
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0045785  positive regulation of cell adhesion
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0033690  positive regulation of osteoblast proliferation
GO:0050764  regulation of phagocytosis
GO:0019048  virus-host interaction

Cellular Component

GO:0009986  cell surface
GO:0009897  external side of plasma membrane
GO:0005887  integral to plasma membrane
GO:0008305  integrin complex
GO:0016020  membrane
GO:0045335  phagocytic vesicle
GO:0005886  plasma membrane

Molecular Function

GO:0031994  insulin-like growth factor I binding
GO:0046872  metal ion binding
GO:0001846  opsonin binding
GO:0005515  protein binding
GO:0005080  protein kinase C binding
GO:0050431  transforming growth factor beta binding
GO:0005245  voltage-gated calcium channel activity