v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

詳細情報を見る

同義遺伝子名

SCFR, Mast/stem cell growth factor receptor precursor, C-Kit, c-kit, Proto-oncogene tyrosine-protein kinase Kit, KIT, CD117 antigen, CD117, c-Kit protein (CD117)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:35.60 小脳:50.40 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:- 網膜:237.30 目:29.40 動脈:- 静脈:66.60 リンパ節:10.10 末梢血:- 脾臓:18.90 胸腺:25.80 骨髄:- 脂肪:40.30 骨:38.40 皮膚:67.20
GeneChip 大脳:7.37 小脳:9.08 脳幹:6.45 脳梁:6.60 松果体:- 末梢神経:6.39 脊柱:7.23 網膜:- 目:- 動脈:6.24 静脈:5.92 リンパ節:6.10 末梢血:- 脾臓:6.33 胸腺:5.80 骨髄:6.50 脂肪:6.73 骨:- 皮膚:7.65
CAGE 大脳:3.29 小脳:- 脳幹:2.33 脳梁:3.00 松果体:1.18 末梢神経:- 脊柱:2.65 網膜:- 目:- 動脈:2.70 静脈:2.22 リンパ節:2.61 末梢血:- 脾臓:1.39 胸腺:1.22 骨髄:- 脂肪:3.21 骨:- 皮膚:-
RNA-seq 大脳:2.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.61 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.73 骨:- 皮膚:-
EST 子宮:27.30 胎盤:7.30 前立腺:22.50 卵巣:670.70 精巣:- 心臓:51.10 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:33.90     肝臓:10.60        肺:48.90    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:- 副腎:- 膵臓:8.90 乳腺:92.90 唾液腺:328.40
GeneChip 子宮:6.79 胎盤:6.10 前立腺:6.53 卵巣:6.69 精巣:6.53 心臓:5.37 骨格筋:5.54 食道:6.63 胃:7.78 腸:6.90 結腸:6.73 肝臓:5.12 肺:8.43 膀胱:- 腎臓:7.31 下垂体:5.90 甲状腺:9.27 副腎:5.14 膵臓:5.70 乳腺:8.92 唾液腺:8.10
CAGE 子宮:3.24 胎盤:2.18 前立腺:3.34 卵巣:3.32 精巣:2.35 心臓:1.49 骨格筋:1.13 食道:3.33 胃:- 腸:3.04 結腸:3.40     肝臓:0.55    肺:3.77 膀胱:3.04 腎臓:3.24 下垂体:1.89 甲状腺:3.71 副腎:- 膵臓:1.42 乳腺:4.03 唾液腺:3.42
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.00 精巣:0.00 心臓:0.00 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.60     肝臓:0.00        肺:1.02    膀胱:- 腎臓:0.58 下垂体:- 甲状腺:1.06 副腎:0.05 膵臓:- 乳腺:0.34 唾液腺:-

IDs

Refseq ID NM_000222
Gene ID 3815
Unigene ID Hs.479754
Probe set ID 205051_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000157404
GTEx ID ENSG00000157404

オーソログ対応遺伝子

マウス[4]  NM_001122733, NM_021099
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0031532  actin cytoskeleton reorganization
GO:0000187  activation of MAPK activity
GO:0060326  cell chemotaxis
GO:0019221  cytokine-mediated signaling pathway
GO:0002371  dendritic cell cytokine production
GO:0050910  detection of mechanical stimulus involved in sensory perception of sound
GO:0035162  embryonic hemopoiesis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0030218  erythrocyte differentiation
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0035234  germ cell programmed cell death
GO:0006687  glycosphingolipid metabolic process
GO:0048565  gut development
GO:0030097  hemopoiesis
GO:0002327  immature B cell differentiation
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030032  lamellipodium assembly
GO:0002320  lymphoid progenitor cell differentiation
GO:0008584  male gonad development
GO:0002551  mast cell chemotaxis
GO:0032762  mast cell cytokine production
GO:0043303  mast cell degranulation
GO:0060374  mast cell differentiation
GO:0070662  mast cell proliferation
GO:0030318  melanocyte differentiation
GO:0002318  myeloid progenitor cell differentiation
GO:0043069  negative regulation of programmed cell death
GO:0048011  nerve growth factor receptor signaling pathway
GO:0001541  ovarian follicle development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0043473  pigmentation
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0046427  positive regulation of JAK-STAT cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0010863  positive regulation of phospholipase C activity
GO:0051091  positive regulation of transcription factor activity
GO:0042511  positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046777  protein amino acid autophosphorylation
GO:0007243  protein kinase cascade
GO:0042127  regulation of cell proliferation
GO:0008360  regulation of cell shape
GO:0048070  regulation of pigmentation during development
GO:0009314  response to radiation
GO:0007165  signal transduction
GO:0007286  spermatid development
GO:0007283  spermatogenesis
GO:0048863  stem cell differentiation
GO:0019827  stem cell maintenance
GO:0030217  T cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0019955  cytokine binding
GO:0046872  metal ion binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004713  protein tyrosine kinase activity
GO:0004716  receptor signaling protein tyrosine kinase activity
GO:0005020  stem cell factor receptor activity
GO:0004714  transmembrane receptor protein tyrosine kinase activity