low density lipoprotein receptor-related protein 6

詳細情報を見る

同義遺伝子名

LRP6, FLJ90062, low density lipoprotein receptor-related protein 6, FLJ90421

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:34.40

小脳:63

脳幹:-

脳梁:58.30

松果体:-

末梢神経:153.40

脊柱:-

網膜:-

目:52.90

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:19.70

脂肪:-

骨:-

皮膚:19.20

GeneChip

大脳:7.49

小脳:7.25

脳幹:7.49

脳梁:7.58

松果体:-

末梢神経:7.75

脊柱:7.45

網膜:-

目:-

動脈:7.58

静脈:7.40

リンパ節:6.83

末梢血:-

脾臓:6.71

胸腺:5.91

骨髄:6.56

脂肪:7.57

骨:-

皮膚:7.15

CAGE

大脳:2.90

小脳:-

脳幹:2.98

脳梁:3.10

松果体:2.80

末梢神経:-

脊柱:2.74

網膜:-

目:-

動脈:3.01

静脈:2.33

リンパ節:1.87

末梢血:-

脾臓:1.74

胸腺:2.13

骨髄:-

脂肪:2.39

骨:-

皮膚:-

RNA-seq

大脳:2.42

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.05

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.20

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:91.10

胎盤:65.60

前立腺:56.30

卵巣:37.30

精巣:13

心臓:127.70

骨格筋:20.10

食道:-

胃:21.20

腸:64.80

結腸:110.20

肝臓:73.90

肺:53.80

膀胱:-

腎臓:72.80

下垂体:116

甲状腺:-

副腎:50.80

膵臓:8.90

乳腺:111.50

唾液腺:-

GeneChip

子宮:7.81

胎盤:7.11

前立腺:7.60

卵巣:7.56

精巣:7.05

心臓:7.58

骨格筋:7.59

食道:7.11

胃:7.77

腸:7.47

結腸:7.38

肝臓:8.38

肺:7.62

膀胱:-

腎臓:7.89

下垂体:7.31

甲状腺:7.23

副腎:7.32

膵臓:7.48

乳腺:7.43

唾液腺:7.73

CAGE

子宮:3.41

胎盤:2.78

前立腺:2.77

卵巣:2.96

精巣:2.79

心臓:2.68

骨格筋:2.63

食道:2.32

胃:-

腸:2.52

結腸:2.65

肝臓:2.95

肺:3.16

膀胱:2.68

腎臓:2.74

下垂体:2.87

甲状腺:2.67

副腎:-

膵臓:2.66

乳腺:2.02

唾液腺:2.99

RNA-seq

子宮:-

胎盤:-

前立腺:2.74

卵巣:3.00

精巣:2.72

心臓:1.93

骨格筋:1.50

食道:-

胃:-

腸:-

結腸:2.98

肝臓:2.66

肺:2.94

膀胱:-

腎臓:3.02

下垂体:-

甲状腺:2.98

副腎:2.04

膵臓:-

乳腺:2.78

唾液腺:-

IDs

Refseq ID	NM_002336
Gene ID	4040
Unigene ID	Hs.584775
Probe set ID	205606_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000070018
GTEx ID	ENSG00000070018

オーソログ対応遺伝子

マウス[2]	NM_008514
ラット[1]	NM_001107892

染色体

12p13.2 [12,268,959 - 12,419,946]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0009952	anterior/posterior pattern formation
GO:0060349	bone morphogenesis
GO:0046849	bone remodeling
GO:0060444	branching involved in mammary gland duct morphogenesis
GO:0042074	cell migration involved in gastrulation
GO:0071397	cellular response to cholesterol
GO:0021587	cerebellum morphogenesis
GO:0021795	cerebral cortex cell migration
GO:0021987	cerebral cortex development
GO:0060026	convergent extension
GO:0048596	embryonic camera-type eye morphogenesis
GO:0042733	embryonic digit morphogenesis
GO:0035115	embryonic forelimb morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0030326	embryonic limb morphogenesis
GO:0009880	embryonic pattern specification
GO:0060059	embryonic retina morphogenesis in camera-type eye
GO:0035261	external genitalia morphogenesis
GO:0060325	face morphogenesis
GO:0021943	formation of radial glial scaffolds
GO:0001702	gastrulation with mouth forming second
GO:0001947	heart looping
GO:0060596	mammary placode formation
GO:0030901	midbrain development
GO:0030917	midbrain-hindbrain boundary development
GO:0050680	negative regulation of epithelial cell proliferation
GO:0045599	negative regulation of fat cell differentiation
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0006469	negative regulation of protein kinase activity
GO:0034392	negative regulation of smooth muscle cell apoptosis
GO:0014033	neural crest cell differentiation
GO:0014029	neural crest formation
GO:0001843	neural tube closure
GO:0042475	odontogenesis of dentine-containing tooth
GO:0060021	palate development
GO:0003344	pericardium morphogenesis
GO:0043065	positive regulation of apoptosis
GO:0045780	positive regulation of bone resorption
GO:0045787	positive regulation of cell cycle
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0045778	positive regulation of ossification
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0090009	primitive streak formation
GO:0021861	radial glial cell differentiation in the forebrain
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport
GO:0060284	regulation of cell development
GO:0045598	regulation of fat cell differentiation
GO:0030278	regulation of ossification
GO:0051593	response to folic acid
GO:0007268	synaptic transmission
GO:0021794	thalamus development
GO:0060535	trachea cartilage morphogenesis
GO:0016055	Wnt receptor signaling pathway
GO:0021874	Wnt receptor signaling pathway in forebrain neuroblast division
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005901	caveola
GO:0043025	cell soma
GO:0009986	cell surface
GO:0031410	cytoplasmic vesicle
GO:0005769	early endosome
GO:0005783	endoplasmic reticulum
GO:0016021	integral to membrane
GO:0005886	plasma membrane
GO:0043235	receptor complex
GO:0045202	synapse

Molecular Function

GO:0034185	apolipoprotein binding
GO:0005109	frizzled binding
GO:0019210	kinase inhibitor activity
GO:0005041	low-density lipoprotein receptor activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0019534	toxin transporter activity
GO:0042813	Wnt receptor activity
GO:0017147	Wnt-protein binding

low density lipoprotein receptor-related protein 6

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function