v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

詳細情報を見る

同義遺伝子名

Tyrosine-protein kinase Lyn, LYN, JTK8, FLJ26625

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:5.46

小脳:6.07

脳幹:5.55

脳梁:5.84

松果体:-

末梢神経:5.73

脊柱:6.08

網膜:-

目:-

動脈:5.97

静脈:5.45

リンパ節:7.46

末梢血:-

脾臓:8.97

胸腺:5.81

骨髄:8.24

脂肪:6.33

骨:-

皮膚:6.11

CAGE

大脳:2.55

小脳:-

脳幹:2.75

脳梁:2.94

松果体:3.31

末梢神経:-

脊柱:3.35

網膜:-

目:-

動脈:3.34

静脈:4.15

リンパ節:4.79

末梢血:-

脾臓:5.29

胸腺:2.42

骨髄:-

脂肪:3.31

骨:-

皮膚:-

RNA-seq

大脳:1.23

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.24

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.73

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:5.99

胎盤:7.12

前立腺:6.19

卵巣:6.31

精巣:5.42

心臓:5.55

骨格筋:5.10

食道:5.84

胃:6.49

腸:6.43

結腸:6.21

肝臓:6.02

肺:7.09

膀胱:-

腎臓:5.55

下垂体:5.91

甲状腺:5.96

副腎:5.71

膵臓:6.39

乳腺:6.03

唾液腺:5.57

CAGE

子宮:2.48

胎盤:3.98

前立腺:2.96

卵巣:2.86

精巣:2.57

心臓:3.22

骨格筋:2.11

食道:2.61

胃:-

腸:3.86

結腸:3.34

肝臓:3.59

肺:4.62

膀胱:3.17

腎臓:2.62

下垂体:2.34

甲状腺:3.18

副腎:-

膵臓:3.29

乳腺:3.54

唾液腺:2.46

RNA-seq

子宮:-

胎盤:-

前立腺:2.06

卵巣:2.08

精巣:2.12

心臓:1.38

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.71

肝臓:2.34

肺:4.03

膀胱:-

腎臓:1.91

下垂体:-

甲状腺:2.15

副腎:3.53

膵臓:-

乳腺:1.91

唾液腺:-

IDs

Refseq ID	NM_002350
Gene ID	4067
Unigene ID	-
Probe set ID	210754_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000254087
GTEx ID	ENSG00000254087

オーソログ対応遺伝子

マウス[4]	NM_001111096, NM_010747
ラット[6]	NM_001111098, NM_030857

染色体

8q12.1 [56,792,372 - 56,923,939]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0030262	apoptotic nuclear changes
GO:0001782	B cell homeostasis
GO:0050853	B cell receptor signaling pathway
GO:0007596	blood coagulation
GO:0031668	cellular response to extracellular stimulus
GO:0034605	cellular response to heat
GO:0071300	cellular response to retinoic acid
GO:0050663	cytokine secretion
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0030218	erythrocyte differentiation
GO:0002774	Fc receptor mediated inhibitory signaling pathway
GO:0002431	Fc receptor mediated stimulatory signaling pathway
GO:0002553	histamine secretion by mast cell
GO:0002768	immune response-regulating cell surface receptor signaling pathway
GO:0045087	innate immune response
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
GO:0050900	leukocyte migration
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0030889	negative regulation of B cell proliferation
GO:0008285	negative regulation of cell proliferation
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0050777	negative regulation of immune response
GO:0043407	negative regulation of MAP kinase activity
GO:0070667	negative regulation of mast cell proliferation
GO:0002762	negative regulation of myeloid leukocyte differentiation
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0010741	negative regulation of protein kinase cascade
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway
GO:0031175	neuron projection development
GO:0014003	oligodendrocyte development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0051272	positive regulation of cellular component movement
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway
GO:0060252	positive regulation of glial cell proliferation
GO:0070668	positive regulation of mast cell proliferation
GO:0010976	positive regulation of neuron projection development
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0070304	positive regulation of stress-activated protein kinase signaling pathway
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0002902	regulation of B cell apoptosis
GO:0050855	regulation of B cell receptor signaling pathway
GO:0033628	regulation of cell adhesion mediated by integrin
GO:0001817	regulation of cytokine production
GO:0050707	regulation of cytokine secretion
GO:0070372	regulation of ERK1 and ERK2 cascade
GO:0045646	regulation of erythrocyte differentiation
GO:0050727	regulation of inflammatory response
GO:0033003	regulation of mast cell activation
GO:0043304	regulation of mast cell degranulation
GO:0090025	regulation of monocyte chemotaxis
GO:0001932	regulation of protein amino acid phosphorylation
GO:0051279	regulation of release of sequestered calcium ion into cytosol
GO:0043200	response to amino acid stimulus
GO:0048678	response to axon injury
GO:0009743	response to carbohydrate stimulus
GO:0006974	response to DNA damage stimulus
GO:0009725	response to hormone stimulus
GO:0032868	response to insulin stimulus
GO:0014070	response to organic cyclic substance
GO:0006991	response to sterol depletion
GO:0009636	response to toxin
GO:0007165	signal transduction
GO:0031295	T cell costimulation
GO:0002513	tolerance induction to self antigen
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0019048	virus-host interaction

Cellular Component

GO:0034666	alpha2-beta1 integrin complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005794	Golgi apparatus
GO:0043231	intracellular membrane-bounded organelle
GO:0045121	membrane raft
GO:0030061	mitochondrial crista
GO:0005758	mitochondrial intermembrane space
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0005524	ATP binding
GO:0019899	enzyme binding
GO:0043208	glycosphingolipid binding
GO:0005178	integrin binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0051219	phosphoprotein binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0005515	protein binding
GO:0004713	protein tyrosine kinase activity
GO:0004716	receptor signaling protein tyrosine kinase activity
GO:0017124	SH3 domain binding
GO:0031625	ubiquitin protein ligase binding

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function