SMAD family member 1

詳細情報を見る

同義遺伝子名

SMAD1, Mothers against DPP homolog 1, MADR1, BSP1, SMAD-1, Mothers against decapentaplegic homolog 1, JV41, hSMAD1, JV4-1, BSP-1, MADH1, Mad-related protein 1, SMAD 1, Smad-1, SMAD, mothers against DPP homolog 1 (Drosophila)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.42 小脳:6.90 脳幹:6.14 脳梁:6.70 松果体:- 末梢神経:6.99 脊柱:7.03 網膜:- 目:- 動脈:6.74 静脈:7.09 リンパ節:7.15 末梢血:- 脾臓:6.76 胸腺:7.10 骨髄:5.86 脂肪:7.83 骨:- 皮膚:7.40
CAGE 大脳:3.33 小脳:- 脳幹:2.93 脳梁:3.28 松果体:3.50 末梢神経:- 脊柱:3.25 網膜:- 目:- 動脈:3.17 静脈:3.09 リンパ節:2.81 末梢血:- 脾臓:2.86 胸腺:3.16 骨髄:- 脂肪:3.63 骨:- 皮膚:-
RNA-seq 大脳:3.55 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.11 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.81 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:8.11 胎盤:6.09 前立腺:7.13 卵巣:7.62 精巣:7.32 心臓:6.63 骨格筋:6.84 食道:7.27 胃:6.96 腸:7.02 結腸:7.40 肝臓:6.59 肺:6.62 膀胱:- 腎臓:6.86 下垂体:6.65 甲状腺:7.37 副腎:5.90 膵臓:6.77 乳腺:8.15 唾液腺:6.83
CAGE 子宮:3.90 胎盤:2.31 前立腺:3.27 卵巣:3.15 精巣:2.93 心臓:2.73 骨格筋:3.46 食道:3.19 胃:- 腸:3.33 結腸:2.97     肝臓:4.04    肺:2.72 膀胱:3.14 腎臓:3.16 下垂体:3.18 甲状腺:3.28 副腎:- 膵臓:3.10 乳腺:2.99 唾液腺:3.34
RNA-seq 子宮:- 胎盤:- 前立腺:3.53 卵巣:3.71 精巣:3.99 心臓:2.00 骨格筋:2.50 食道:- 胃:- 腸:- 結腸:3.20     肝臓:3.33        肺:3.20    膀胱:- 腎臓:3.19 下垂体:- 甲状腺:3.71 副腎:4.63 膵臓:- 乳腺:3.65 唾液腺:-

IDs

Refseq ID NM_001003688
Gene ID 4086
Unigene ID Hs.604588
Probe set ID 210993_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170365
GTEx ID ENSG00000170365

オーソログ対応遺伝子

マウス[2]  NM_008539
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8637600
8653785
8663601
8673135
8774881
8893010
9006934
9111321
9136927
9256479
9335504
9335505
9389648
9393997
9436979
9748228
9759503
9843199
10085121
10199400
10205054
10224145
10400677
10400705
10497242
10531362
10583507
10647776
10652350
10660046
10673036
10708948
10708949
10887155
10890911
10962029
11016919
11094085
11118211
11121043
11139569
11158580
11163184
11239394
11278251
11387330
11438941
11451566
11483516
11571290
11700304
11779505
11811554
12097147
12167862
12354674
12370310
12426322
12477932
12519765
12649288
12650946
12714599
12743038
12808092
12821673
12857866
12874272
12904571
12944489
14500836
14612411
14630787
14633973
14699069
14701756
14702039
14732718
15009097
15107829
15221015
15231748
15246821
15359284
15489334
15489854
15516492
15542835
15613244
15621726
15647271
15708501
15761153
15781469
15849193
15877825
15911698
16087734
16247476
16326713
16412560
16436528
16611643
16613856
16621789
16931515
16990609
17043655
17183365
17215250
17251190
17289590
17292623
17356069
17359969
17392271
17452325
17455258
17496924
17510966
17676934
17847004
17948051
17963781
18045539
18160706
18184649
18310319
18321803
18393632
18425117
18668566
18684712
18729074
18769113
18775991
19018011
19056927
19135894
19211612
19224917
19244313
19247629
19269967
19416967
19424179
19453261
19513897
19592636
19664780
19819941
19914168
19917253
19959123
19996292
20211142
20388715
20460105
20522807
20565840
20634891
20667911
20734064
20819778
20851880
20937913
21068203
21308777
21344387
21360446
21405981
21440420
21445358
21453705
21454478
21515822
21685363
21708152
21760921
21832049
21890473
21900206
21945631
21947082
22073863
22277251
22299030
22344298
22393057
22452883
22474288
22550179
22588298
22615489
22670624
22868198
22897816
22964636
23088614
23333304
23344957
23387849
23707512
23734213
23800974
23804438
23918166
24008158
24021264
24347165
24828823

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway
GO:0060348  bone development
GO:0060038  cardiac muscle cell proliferation
GO:0051216  cartilage development
GO:0009880  embryonic pattern specification
GO:0007276  gamete generation
GO:0030902  hindbrain development
GO:0042592  homeostatic process
GO:0006954  inflammatory response
GO:0001822  kidney development
GO:0000165  MAPKKK cascade
GO:0001710  mesodermal cell fate commitment
GO:0030901  midbrain development
GO:0008285  negative regulation of cell proliferation
GO:0002051  osteoblast fate commitment
GO:0050775  positive regulation of dendrite morphogenesis
GO:0010628  positive regulation of gene expression
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0031053  primary microRNA processing
GO:0006468  protein amino acid phosphorylation
GO:0042493  response to drug
GO:0010243  response to organic nitrogen
GO:0007165  signal transduction
GO:0007183  SMAD protein complex assembly
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001657  ureteric bud development
GO:0042060  wound healing

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016021  integral to membrane
GO:0005622  intracellular
GO:0005637  nuclear inner membrane
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0070410  co-SMAD binding
GO:0070411  I-SMAD binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0005057  receptor signaling protein activity
GO:0003700  transcription factor activity
GO:0030618  transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity