methyl CpG binding protein 2 (Rett syndrome)

同義遺伝子名

AUTSX3, RTT, DKFZp686A24160, PPMX, Methyl-CpG-binding protein 2, methyl CpG binding protein 2 (Rett syndrome), MRX79, MeCP2, MECP2, MRX16, MeCP-2 protein

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:5.87

小脳:5.86

脳幹:5.91

脳梁:5.91

松果体:-

末梢神経:5.88

脊柱:5.75

網膜:-

目:-

動脈:6.19

静脈:6.53

リンパ節:6.27

末梢血:-

脾臓:6.18

胸腺:6

骨髄:6.46

脂肪:6.22

骨:-

皮膚:6.32

CAGE

大脳:4.11

小脳:-

脳幹:3.96

脳梁:3.90

松果体:4.35

末梢神経:-

脊柱:4.25

網膜:-

目:-

動脈:3.95

静脈:3.82

リンパ節:3.44

末梢血:-

脾臓:3.81

胸腺:3.48

骨髄:-

脂肪:3.56

骨:-

皮膚:-

RNA-seq

大脳:0.00

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.53

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.12

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:6.02

胎盤:5.82

前立腺:5.95

卵巣:6.18

精巣:5.76

心臓:6.38

骨格筋:6.31

食道:6.17

胃:6.08

腸:6.33

結腸:6.21

肝臓:6.11

肺:6.24

膀胱:-

腎臓:6.11

下垂体:5.99

甲状腺:5.89

副腎:6.30

膵臓:6.44

乳腺:5.88

唾液腺:6.45

CAGE

子宮:3.88

胎盤:2.98

前立腺:3.81

卵巣:3.98

精巣:3.48

心臓:3.65

骨格筋:3.68

食道:3.48

胃:-

腸:3.28

結腸:3.31

肝臓:3.10

肺:3.64

膀胱:3.96

腎臓:3.37

下垂体:3.76

甲状腺:3.63

副腎:-

膵臓:3.67

乳腺:3.38

唾液腺:3.57

RNA-seq

子宮:-

胎盤:-

前立腺:1.63

卵巣:0.00

精巣:0.29

心臓:1.08

骨格筋:3.39

食道:-

胃:-

腸:-

結腸:2.69

肝臓:1.04

肺:3.84

膀胱:-

腎臓:0.00

下垂体:-

甲状腺:1.18

副腎:1.95

膵臓:-

乳腺:0.00

唾液腺:-

IDs

Refseq ID	NM_001110792
Gene ID	4204
Unigene ID	-
Probe set ID	202618_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000169057
GTEx ID	ENSG00000169057

オーソログ対応遺伝子

マウス[8]	NM_001081979, NM_010788
ラット [0]

染色体

Xq28 [153,287,024 - 153,402,578]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR016177	DNA-binding, integrase-type
IPR001739	Methyl-CpG DNA binding

遺伝子オントロジー (GO ID)

Biological Process

GO:0008344	adult locomotory behavior
GO:0001662	behavioral fear response
GO:0032048	cardiolipin metabolic process
GO:0050432	catecholamine secretion
GO:0021549	cerebellum development
GO:0006342	chromatin silencing
GO:0016358	dendrite development
GO:0009790	embryonic development
GO:0006349	genetic imprinting
GO:0008211	glucocorticoid metabolic process
GO:0006541	glutamine metabolic process
GO:0016573	histone acetylation
GO:0016571	histone methylation
GO:0006020	inositol metabolic process
GO:0007616	long-term memory
GO:0060291	long-term synaptic potentiation
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
GO:0035067	negative regulation of histone acetylation
GO:0031061	negative regulation of histone methylation
GO:0043524	negative regulation of neuron apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure
GO:0042551	neuron maturation
GO:0009405	pathogenesis
GO:0046470	phosphatidylcholine metabolic process
GO:0008284	positive regulation of cell proliferation
GO:0051965	positive regulation of synaptogenesis
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0019230	proprioception
GO:0008104	protein localization
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0007585	respiratory gaseous exchange
GO:0001666	response to hypoxia
GO:0019233	sensory perception of pain
GO:0035176	social behavior
GO:0001964	startle response
GO:0007416	synapse assembly
GO:0006351	transcription, DNA-dependent
GO:0021591	ventricular system development
GO:0008542	visual learning

Cellular Component

GO:0005829	cytosol
GO:0000792	heterochromatin
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0010385	double-stranded methylated DNA binding
GO:0008327	methyl-CpG binding
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0047485	protein N-terminus binding
GO:0035197	siRNA binding
GO:0003714	transcription corepressor activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

methyl CpG binding protein 2 (Rett syndrome)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function