macrophage migration inhibitory factor (glycosylation-inhibiting factor)

詳細情報を見る

同義遺伝子名

Glycosylation-inhibiting factor, GLIF, MMIF

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:109 小脳:- 脳幹:- 脳梁:- 松果体:445 末梢神経:30.70 脊柱:- 網膜:593.20 目:293.80 動脈:119.90 静脈:733.10 リンパ節:323.50 末梢血:72.90 脾臓:75.60 胸腺:64.40 骨髄:59 脂肪:242 骨:38.40 皮膚:148.80
GeneChip 大脳:9.73 小脳:8.75 脳幹:9.93 脳梁:9.03 松果体:- 末梢神経:9.35 脊柱:9.83 網膜:- 目:- 動脈:9.43 静脈:9.27 リンパ節:9.49 末梢血:- 脾臓:8.89 胸腺:9.67 骨髄:8.46 脂肪:8.97 骨:- 皮膚:9.95
CAGE 大脳:6.02 小脳:- 脳幹:5.47 脳梁:4.99 松果体:5.60 末梢神経:- 脊柱:6.44 網膜:- 目:- 動脈:6.27 静脈:6.04 リンパ節:6.33 末梢血:- 脾臓:5.44 胸腺:5.39 骨髄:- 脂肪:4.98 骨:- 皮膚:-
RNA-seq 大脳:6.32 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:7.38 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:7.10 骨:- 皮膚:-
EST 子宮:191.40 胎盤:193.10 前立腺:169 卵巣:- 精巣:129.80 心臓:332.10 骨格筋:20.10 食道:- 胃:- 腸:97.20 結腸:76.30     肝臓:52.80        肺:141.70    膀胱:- 腎臓:187.10 下垂体:347.90 甲状腺:- 副腎:203.10 膵臓:195.60 乳腺:27.90 唾液腺:-
GeneChip 子宮:9.51 胎盤:9.64 前立腺:10.60 卵巣:10.23 精巣:9.36 心臓:9.12 骨格筋:7.16 食道:10.30 胃:9.10 腸:9.34 結腸:9.48 肝臓:9.60 肺:9.02 膀胱:- 腎臓:10.42 下垂体:10.07 甲状腺:9.87 副腎:9.88 膵臓:9.83 乳腺:9.91 唾液腺:9.22
CAGE 子宮:5.14 胎盤:5.89 前立腺:5.53 卵巣:5.51 精巣:5.79 心臓:6.31 骨格筋:5.27 食道:6.10 胃:- 腸:5.05 結腸:5.89     肝臓:6.46    肺:6.12 膀胱:5.62 腎臓:5.95 下垂体:6.06 甲状腺:5.86 副腎:- 膵臓:6.83 乳腺:6.86 唾液腺:5.49
RNA-seq 子宮:- 胎盤:- 前立腺:7.70 卵巣:7.49 精巣:7.71 心臓:5.44 骨格筋:5.27 食道:- 胃:- 腸:- 結腸:7.39     肝臓:6.85        肺:7.33    膀胱:- 腎臓:7.93 下垂体:- 甲状腺:7.73 副腎:7.73 膵臓:- 乳腺:6.83 唾液腺:-

IDs

Refseq ID NM_002415
Gene ID 4282
Unigene ID Hs.407995
Probe set ID 217871_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000240972
GTEx ID ENSG00000240972

オーソログ対応遺伝子

マウス[1]  NM_010798
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1286669
2552447
3917866
7558020
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0019752  carboxylic acid metabolic process
GO:0007569  cell aging
GO:0008283  cell proliferation
GO:0007166  cell surface receptor linked signal transduction
GO:0030330  DNA damage response, signal transduction by p53 class mediator
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0043066  negative regulation of apoptosis
GO:0071157  negative regulation of cell cycle arrest
GO:0032269  negative regulation of cellular protein metabolic process
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0010629  negative regulation of gene expression
GO:0002906  negative regulation of mature B cell apoptosis
GO:0033033  negative regulation of myeloid cell apoptosis
GO:0050918  positive chemotaxis
GO:0030890  positive regulation of B cell proliferation
GO:0050715  positive regulation of cytokine secretion
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0031666  positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043406  positive regulation of MAP kinase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0042327  positive regulation of phosphorylation
GO:0010739  positive regulation of protein kinase A signaling cascade
GO:0001516  prostaglandin biosynthetic process
GO:0070207  protein homotrimerization
GO:0043030  regulation of macrophage activation

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0005126  cytokine receptor binding
GO:0004167  dopachrome isomerase activity
GO:0050178  phenylpyruvate tautomerase activity
GO:0005515  protein binding
GO:0005102  receptor binding