neural precursor cell expressed, developmentally down-regulated 4

詳細情報を見る

同義遺伝子名

KIAA0093, E3 ubiquitin-protein ligase NEDD4, NEDD4

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:11.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:17.60 動脈:- 静脈:- リンパ節:20.20 末梢血:18.20 脾臓:- 胸腺:- 骨髄:19.70 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.11 小脳:4.03 脳幹:4.07 脳梁:4.28 松果体:- 末梢神経:4.38 脊柱:4.19 網膜:- 目:- 動脈:5.12 静脈:4.87 リンパ節:4.49 末梢血:- 脾臓:4.63 胸腺:4.64 骨髄:4.71 脂肪:4.94 骨:- 皮膚:5.08
CAGE 大脳:1.89 小脳:- 脳幹:2.34 脳梁:2.35 松果体:2.94 末梢神経:- 脊柱:2.98 網膜:- 目:- 動脈:3.32 静脈:2.57 リンパ節:2.11 末梢血:- 脾臓:2.82 胸腺:3.07 骨髄:- 脂肪:3.68 骨:- 皮膚:-
RNA-seq 大脳:0.82 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.09 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.57 骨:- 皮膚:-
EST 子宮:- 胎盤:21.90 前立腺:- 卵巣:37.30 精巣:- 心臓:- 骨格筋:20.10 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:19.60    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:9.30 唾液腺:-
GeneChip 子宮:5.23 胎盤:6.29 前立腺:4.90 卵巣:4.75 精巣:3.72 心臓:4.93 骨格筋:7.79 食道:4.99 胃:4.62 腸:5.20 結腸:4.60 肝臓:5.75 肺:5.11 膀胱:- 腎臓:4.42 下垂体:4.07 甲状腺:4.73 副腎:4.61 膵臓:4.22 乳腺:5.01 唾液腺:4.14
CAGE 子宮:3.44 胎盤:3.94 前立腺:3.30 卵巣:2.91 精巣:2.04 心臓:3.07 骨格筋:4.29 食道:3.17 胃:- 腸:3.69 結腸:3.04     肝臓:3.33    肺:3.28 膀胱:3.48 腎臓:3.19 下垂体:2.71 甲状腺:2.62 副腎:- 膵臓:1.74 乳腺:3.24 唾液腺:2.06
RNA-seq 子宮:- 胎盤:- 前立腺:2.83 卵巣:2.14 精巣:2.04 心臓:1.58 骨格筋:4.11 食道:- 胃:- 腸:- 結腸:2.62     肝臓:2.66        肺:2.59    膀胱:- 腎臓:2.32 下垂体:- 甲状腺:2.44 副腎:1.97 膵臓:- 乳腺:2.01 唾液腺:-

IDs

Refseq ID NM_006154
Gene ID 4734
Unigene ID Hs.156506
Probe set ID 213012_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000069869
GTEx ID ENSG00000069869

オーソログ対応遺伝子

マウス[3]  NM_010890
ラット[1]  NM_012986

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7788527
8649367
9073511
9182527
9305852
9351815
9405440
9525617
9593687
9990509
10037602
10212229
10446181
10642508
10871286
11042109
11046148
11087859
11087860
11112487
11244092
11323714
11342538
11359767
11502596
11598133
11696533
11717310
11748237
11919637
11991975
12050153
12167593
12218189
12230472
12477932
12610113
12697834
12729930
12796489
12907594
12907674
14581525
14645220
14973438
15001356
15013426
15060076
15126635
15217910
15231748
15252135
15496141
15548568
15677482
15678106
15703212
16055720
16118794
16138902
16169070
16338389
16572171
16701206
16867982
16885233
17013377
17116753
17218260
17218261
17289006
17538020
17544362
17719543
17996703
18174164
18287095
18305167
18307411
18353951
18498243
18498246
18544533
18577513
18632619
18703514
18723765
18772139
18804462
18854154
19020832
19024597
19054764
19125695
19143627
19158374
19165858
19193720
19240029
19252184
19343052
19345329
19366705
19602703
19615332
19617352
19670909
19706893
19812267
19835589
19835873
19864419
19907029
19953087
20051513
20062064
20078934
20086093
20159449
20164219
20172859
20237237
20332230
20519395
20522958
20530479
20559325
20562859
20675381
20676133
20697350
20711176
20730100
20737472
20819705
20843805
20855896
20889565
21148011
21191027
21308777
21332718
21338354
21399620
21463633
21478478
21572392
21666754
21685363
21765395
21813641
21852580
21890473
21906983
21936852
21953697
21986318
21987572
22004035
22024150
22096579
22350919
22361880
22385262
22467858
22751010
22761998
22762019
22768111
22773947
22875931
22939629
22974840
22992774
23000965
23071112
23106887
23166351
23180960
23195959
23236378
23253940
23262292
23287719
23305486
23460917
23471985
23549616
23589096
23602387
23603909
23639431
23644597
23665454
23964096
24063548
24141722
24292274
24340059
24379409
24413081
24614057
24657926
24662824
24743017
24816145
24831002

遺伝子オントロジー  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0048514  blood vessel morphogenesis
GO:0034644  cellular response to UV
GO:0019221  cytokine-mediated signaling pathway
GO:0044111  development during symbiotic interaction
GO:0003197  endocardial cushion development
GO:0042921  glucocorticoid receptor signaling pathway
GO:0007041  lysosomal transport
GO:0010766  negative regulation of sodium ion transport
GO:0010768  negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0030948  negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0007528  neuromuscular junction development
GO:0031175  neuron projection development
GO:0003151  outflow tract morphogenesis
GO:0046824  positive regulation of nucleocytoplasmic transport
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0045732  positive regulation of protein catabolic process
GO:0050847  progesterone receptor signaling pathway
GO:0070534  protein K63-linked ubiquitination
GO:0006513  protein monoubiquitination
GO:0006622  protein targeting to lysosome
GO:0016567  protein ubiquitination
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0032801  receptor catabolic process
GO:0031623  receptor internalization
GO:0048814  regulation of dendrite morphogenesis
GO:0034765  regulation of ion transmembrane transport
GO:0042391  regulation of membrane potential
GO:0050807  regulation of synapse organization
GO:0051592  response to calcium ion
GO:0042110  T cell activation
GO:0019089  transmission of virus
GO:0043162  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0019048  virus-host interaction

Cellular Component

GO:0016327  apicolateral plasma membrane
GO:0005938  cell cortex
GO:0000785  chromatin
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0000151  ubiquitin ligase complex

Molecular Function

GO:0031698  beta-2 adrenergic receptor binding
GO:0050815  phosphoserine binding
GO:0050816  phosphothreonine binding
GO:0070064  proline-rich region binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0070063  RNA polymerase binding
GO:0019871  sodium channel inhibitor activity
GO:0043130  ubiquitin binding
GO:0004842  ubiquitin-protein ligase activity