neurofibromin 1

詳細情報を見る

同義遺伝子名

VRNF, WSS, Neurofibromin, NFNS, DKFZp686J1293, NF1, Neurofibromatosis-related protein NF-1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:51

小脳:12.60

脳幹:-

脳梁:29.20

松果体:148.30

末梢神経:-

脊柱:-

網膜:-

目:117.50

動脈:-

静脈:-

リンパ節:70.80

末梢血:18.20

脾臓:-

胸腺:25.80

骨髄:-

脂肪:-

骨:-

皮膚:62.40

GeneChip

大脳:3.27

小脳:3.26

脳幹:3.32

脳梁:3.42

松果体:-

末梢神経:3.29

脊柱:3.51

網膜:-

目:-

動脈:3.36

静脈:3.32

リンパ節:3.27

末梢血:-

脾臓:3.13

胸腺:3.10

骨髄:3.39

脂肪:3.40

骨:-

皮膚:3.32

CAGE

大脳:4.63

小脳:-

脳幹:4.51

脳梁:4.38

松果体:4.92

末梢神経:-

脊柱:4.55

網膜:-

目:-

動脈:4.06

静脈:3.95

リンパ節:3.22

末梢血:-

脾臓:3.98

胸腺:3.85

骨髄:-

脂肪:3.98

骨:-

皮膚:-

RNA-seq

大脳:1.04

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.29

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.49

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:18.20

前立腺:11.30

卵巣:-

精巣:21.60

心臓:38.30

骨格筋:-

食道:-

胃:-

腸:-

結腸:17

肝臓:-

肺:48.90

膀胱:-

腎臓:31.20

下垂体:-

甲状腺:-

副腎:-

膵臓:88.90

乳腺:-

唾液腺:-

GeneChip

子宮:3.23

胎盤:3.14

前立腺:3.26

卵巣:3.24

精巣:3.31

心臓:3.24

骨格筋:3.20

食道:3.25

胃:3.14

腸:3.39

結腸:3.22

肝臓:3.23

肺:3.24

膀胱:-

腎臓:3.27

下垂体:3.59

甲状腺:3.63

副腎:3.27

膵臓:3.40

乳腺:3.36

唾液腺:3.31

CAGE

子宮:4.15

胎盤:4.13

前立腺:4.05

卵巣:3.92

精巣:4.37

心臓:4.17

骨格筋:3.95

食道:3.75

胃:-

腸:4.07

結腸:3.82

肝臓:3.81

肺:4.10

膀胱:4.12

腎臓:4.09

下垂体:4.58

甲状腺:4.00

副腎:-

膵臓:3.65

乳腺:4.10

唾液腺:3.88

RNA-seq

子宮:-

胎盤:-

前立腺:0.28

卵巣:0.18

精巣:0.43

心臓:0.05

骨格筋:0

食道:-

胃:-

腸:-

結腸:0.05

肝臓:0.05

肺:0.59

膀胱:-

腎臓:0.12

下垂体:-

甲状腺:1.79

副腎:0.48

膵臓:-

乳腺:0.37

唾液腺:-

IDs

Refseq ID	NM_001128147
Gene ID	4763
Unigene ID	Hs.113577
Probe set ID	210631_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000196712
GTEx ID	ENSG00000196712

オーソログ対応遺伝子

マウス[2]	NM_010897
ラット [0]

染色体

17q11.2 [29,421,945 - 29,708,905]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001936	Ras GTPase-activating protein
IPR008936	Rho GTPase activation protein

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0030325	adrenal gland development
GO:0048844	artery morphogenesis
GO:0007420	brain development
GO:0048593	camera-type eye morphogenesis
GO:0007154	cell communication
GO:0021987	cerebral cortex development
GO:0050890	cognition
GO:0030199	collagen fibril organization
GO:0030198	extracellular matrix organization
GO:0021897	forebrain astrocyte development
GO:0048853	forebrain morphogenesis
GO:0007507	heart development
GO:0001889	liver development
GO:0000165	MAPKKK cascade
GO:0001656	metanephros development
GO:0022011	myelination in the peripheral nervous system
GO:0016525	negative regulation of angiogenesis
GO:0048712	negative regulation of astrocyte differentiation
GO:0030336	negative regulation of cell migration
GO:0001953	negative regulation of cell-matrix adhesion
GO:0001937	negative regulation of endothelial cell proliferation
GO:0048147	negative regulation of fibroblast proliferation
GO:0043407	negative regulation of MAP kinase activity
GO:0043409	negative regulation of MAPKKK cascade
GO:0007406	negative regulation of neuroblast proliferation
GO:0046929	negative regulation of neurotransmitter secretion
GO:0048715	negative regulation of oligodendrocyte differentiation
GO:0045671	negative regulation of osteoclast differentiation
GO:0006469	negative regulation of protein kinase activity
GO:0035021	negative regulation of Rac protein signal transduction
GO:0046580	negative regulation of Ras protein signal transduction
GO:0042992	negative regulation of transcription factor import into nucleus
GO:0021915	neural tube development
GO:0001649	osteoblast differentiation
GO:0007422	peripheral nervous system development
GO:0014065	phosphoinositide 3-kinase cascade
GO:0043473	pigmentation
GO:0045762	positive regulation of adenylate cyclase activity
GO:0043065	positive regulation of apoptosis
GO:0001938	positive regulation of endothelial cell proliferation
GO:0043525	positive regulation of neuron apoptosis
GO:0032320	positive regulation of Ras GTPase activity
GO:0007265	Ras protein signal transduction
GO:0045765	regulation of angiogenesis
GO:0043535	regulation of blood vessel endothelial cell migration
GO:0045124	regulation of bone resorption
GO:0001952	regulation of cell-matrix adhesion
GO:0045685	regulation of glial cell differentiation
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0032318	regulation of Ras GTPase activity
GO:0032228	regulation of synaptic transmission, GABAergic
GO:0001666	response to hypoxia
GO:0014044	Schwann cell development
GO:0007519	skeletal muscle tissue development
GO:0048745	smooth muscle tissue development
GO:0021510	spinal cord development
GO:0048485	sympathetic nervous system development
GO:0008542	visual learning
GO:0042060	wound healing

Cellular Component

GO:0030424	axon
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0031235	intrinsic to internal side of plasma membrane
GO:0005634	nucleus

Molecular Function

GO:0005515	protein binding
GO:0005099	Ras GTPase activator activity

neurofibromin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function