neurotrophic tyrosine kinase, receptor, type 1

同義遺伝子名

TRK1, MTC, Trk-A, TrkA neurotrophin receptor, TRK, TRKA, TRK1 transforming tyrosine kinase protein, p140-TrkA, DKFZp781I14186, neurotrophic tyrosine kinase, receptor, type 1, Neurotrophic tyrosine kinase receptor type 1, NTRK1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:5.90

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:224.60

網膜:-

目:23.50

動脈:-

静脈:-

リンパ節:10.10

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:4.80

GeneChip

大脳:3.58

小脳:3.73

脳幹:4.30

脳梁:3.36

松果体:-

末梢神経:6.59

脊柱:3.30

網膜:-

目:-

動脈:3.45

静脈:3.87

リンパ節:3.48

末梢血:-

脾臓:3.17

胸腺:2.90

骨髄:3.55

脂肪:3.68

骨:-

皮膚:3.72

CAGE

大脳:0.27

小脳:-

脳幹:1.50

脳梁:0.07

松果体:3.23

末梢神経:-

脊柱:0.47

網膜:-

目:-

動脈:0.47

静脈:0.70

リンパ節:0.12

末梢血:-

脾臓:0

胸腺:0.12

骨髄:-

脂肪:0

骨:-

皮膚:-

RNA-seq

大脳:0.05

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.11

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:27.30

胎盤:18.20

前立腺:22.50

卵巣:-

精巣:17.30

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:50.80

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:3.38

胎盤:2.91

前立腺:3.26

卵巣:3.40

精巣:3.39

心臓:3.83

骨格筋:3.78

食道:3.40

胃:3.35

腸:3.58

結腸:3.54

肝臓:3.41

肺:3.52

膀胱:-

腎臓:3.45

下垂体:3.36

甲状腺:3.16

副腎:3.51

膵臓:3.83

乳腺:3.40

唾液腺:3.38

CAGE

子宮:0.46

胎盤:0.08

前立腺:0.58

卵巣:0.14

精巣:0.76

心臓:0.17

骨格筋:0.05

食道:0.33

胃:-

腸:0.21

結腸:0.08

肝臓:0

肺:0.71

膀胱:0.33

腎臓:0.44

下垂体:0.10

甲状腺:0.12

副腎:-

膵臓:0

乳腺:0

唾液腺:0

RNA-seq

子宮:-

胎盤:-

前立腺:0.40

卵巣:0.04

精巣:0.64

心臓:0.13

骨格筋:0.04

食道:-

胃:-

腸:-

結腸:0.18

肝臓:0.00

肺:0.25

膀胱:-

腎臓:0.11

下垂体:-

甲状腺:0.07

副腎:0.14

膵臓:-

乳腺:0.03

唾液腺:-

IDs

Refseq ID	NM_001007792
Gene ID	4914
Unigene ID	Hs.406293
Probe set ID	208605_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198400
GTEx ID	ENSG00000198400

オーソログ対応遺伝子

マウス[1]	NM_001033124
ラット [0]

染色体

1q23.1 [156,785,432 - 156,851,642]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020777	Tyrosine-protein kinase, neurotrophic receptor
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0000186	activation of MAPKK activity
GO:0007202	activation of phospholipase C activity
GO:0007568	aging
GO:0007411	axon guidance
GO:0060385	axonogenesis involved in innervation
GO:0030183	B cell differentiation
GO:0071316	cellular response to nicotine
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
GO:0050965	detection of temperature stimulus involved in sensory perception of pain
GO:0010623	developmental programmed cell death
GO:0007611	learning or memory
GO:0042490	mechanoreceptor differentiation
GO:0008285	negative regulation of cell proliferation
GO:0043524	negative regulation of neuron apoptosis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0021553	olfactory nerve development
GO:0048015	phosphoinositide-mediated signaling
GO:0045766	positive regulation of angiogenesis
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0010976	positive regulation of neuron projection development
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0043068	positive regulation of programmed cell death
GO:0032320	positive regulation of Ras GTPase activity
GO:0046579	positive regulation of Ras protein signal transduction
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0007265	Ras protein signal transduction
GO:0014823	response to activity
GO:0048678	response to axon injury
GO:0042493	response to drug
GO:0051602	response to electrical stimulus
GO:0045471	response to ethanol
GO:0051599	response to hydrostatic pressure
GO:0031667	response to nutrient levels
GO:0009314	response to radiation
GO:0060009	Sertoli cell development
GO:0007264	small GTPase mediated signal transduction
GO:0048485	sympathetic nervous system development
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0009986	cell surface
GO:0031410	cytoplasmic vesicle
GO:0030425	dendrite
GO:0005769	early endosome
GO:0031901	early endosome membrane
GO:0005768	endosome
GO:0005887	integral to plasma membrane
GO:0005770	late endosome
GO:0005886	plasma membrane
GO:0043234	protein complex

Molecular Function

GO:0005524	ATP binding
GO:0046875	ephrin receptor binding
GO:0048406	nerve growth factor binding
GO:0010465	nerve growth factor receptor activity
GO:0043121	neurotrophin binding
GO:0005166	neurotrophin p75 receptor binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004714	transmembrane receptor protein tyrosine kinase activity

neurotrophic tyrosine kinase, receptor, type 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function