neurotrophic tyrosine kinase, receptor, type 2

詳細情報を見る

同義遺伝子名

NTRK2, BDNF/NT-3 growth factors receptor precursor, Trk-B, GP145-TrkB, TrkB tyrosine kinase, TRKB, neurotrophic tyrosine kinase, receptor, type 2, Neurotrophic tyrosine kinase receptor type 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:403 小脳:239.30 脳幹:- 脳梁:175 松果体:148.30 末梢神経:153.40 脊柱:- 網膜:355.90 目:164.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:75.60 胸腺:25.80 骨髄:- 脂肪:40.30 骨:179.10 皮膚:72
GeneChip 大脳:6.23 小脳:5.98 脳幹:5.97 脳梁:5.81 松果体:- 末梢神経:5.63 脊柱:5.87 網膜:- 目:- 動脈:5.64 静脈:5.48 リンパ節:5.29 末梢血:- 脾臓:5.31 胸腺:5.33 骨髄:5.81 脂肪:5.53 骨:- 皮膚:5.45
CAGE 大脳:6.15 小脳:- 脳幹:5.56 脳梁:5.89 松果体:4.29 末梢神経:- 脊柱:5.92 網膜:- 目:- 動脈:3.56 静脈:3.63 リンパ節:2.13 末梢血:- 脾臓:2.19 胸腺:1.28 骨髄:- 脂肪:4.55 骨:- 皮膚:-
RNA-seq 大脳:3.06 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.13 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.07 骨:- 皮膚:-
EST 子宮:82 胎盤:10.90 前立腺:33.80 卵巣:- 精巣:21.60 心臓:166 骨格筋:- 食道:- 胃:21.20 腸:32.40 結腸:50.90     肝臓:21.10        肺:68.40    膀胱:- 腎臓:31.20 下垂体:116 甲状腺:- 副腎:50.80 膵臓:35.60 乳腺:65.10 唾液腺:-
GeneChip 子宮:5.32 胎盤:5.44 前立腺:5.40 卵巣:5.32 精巣:5.37 心臓:5.42 骨格筋:5.77 食道:5.42 胃:5.45 腸:5.44 結腸:5.42 肝臓:5.32 肺:5.38 膀胱:- 腎臓:5.39 下垂体:5.70 甲状腺:5.58 副腎:5.40 膵臓:5.31 乳腺:5.46 唾液腺:5.49
CAGE 子宮:3.07 胎盤:0.88 前立腺:2.50 卵巣:3.41 精巣:2.48 心臓:3.44 骨格筋:2.09 食道:2.76 胃:- 腸:1.27 結腸:1.96     肝臓:1.21    肺:1.76 膀胱:3.18 腎臓:3.48 下垂体:3.49 甲状腺:4.83 副腎:- 膵臓:3.90 乳腺:3.76 唾液腺:2.85
RNA-seq 子宮:- 胎盤:- 前立腺:0.13 卵巣:0.16 精巣:0.19 心臓:0.10 骨格筋:0.04 食道:- 胃:- 腸:- 結腸:0.20     肝臓:0.00        肺:0.05    膀胱:- 腎臓:0.27 下垂体:- 甲状腺:0.54 副腎:0.17 膵臓:- 乳腺:0.58 唾液腺:-

IDs

Refseq ID NM_001018064
Gene ID 4915
Unigene ID Hs.494312
Probe set ID 207152_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000148053
GTEx ID ENSG00000148053

オーソログ対応遺伝子

マウス[3]  NM_001025074, NM_008745
ラット[3]  NM_001163168, NM_001163169, NM_012731

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1645620
1710174
7574684
7679912
7759111
7789988
7823156
7936202
8621424
8895847
9195161
9312147
9507002
9573364
9648856
9856458
9927421
10092678
10386953
10388563
10490030
10533983
10631974
11157096
11162451
11251075
11263982
11432792
11738045
11798182
11849294
11855816
12006576
12074588
12237455
12367511
12419535
12471037
12477932
12719654
12808116
12912764
12921913
14617818
14702039
15024057
15167895
15304335
15329723
15389758
15489334
15494731
15513915
15637590
15647480
15657181
15838534
16034442
16051641
16113645
16335952
16647839
16648150
16701206
16713371
16713586
16786155
16805430
16862449
16939974
16964397
17008023
17200667
17570738
17611278
17616679
17674765
17720314
17873329
17884018
17889702
17918233
17971243
18075316
18201274
18203754
18253057
18286198
18293376
18319596
18428117
18457658
18511296
18534558
18595003
18637190
18678285
18727839
18780967
18959266
18992902
19018715
19086053
19087522
19124685
19156168
19170129
19268276
19307055
19363525
19365399
19386345
19403818
19417027
19453261
19488044
19548263
19598235
19635108
19641488
19741136
19765683
19801649
19816090
19844206
19874574
19879330
19885622
19913121
19927149
19953087
20014955
20083228
20101235
20124106
20132184
20156366
20186105
20193039
20202475
20219210
20379614
20428771
20463055
20468064
20610389
20615547
20628086
20662941
20673758
20694504
20703101
20811716
20877300
20878119
21047554
21079983
21126736
21187387
21192928
21215389
21223646
21239439
21242122
21295543
21330466
21379385
21414899
21419569
21426646
21552290
21612826
21670725
21711518
21728718
21739244
21750702
21795612
21802740
21849537
21849550
21966426
21988832
21999199
22020324
22028443
22209410
22258407
22322843
22341689
22343487
22361863
22393127
22425982
22426239
22490895
22609366
22710966
22719055
22842573
22886570
22902478
22906736
22939624
23058367
23064382
23086941
23124249
23137999
23185507
23185968
23192594
23277131
23315174
23332094
23380313
23416450
23420490
23422506
23598407
23656788
23831349
23861540
23869086
23936232
24047966
24069289
24086766
24321270
24795586
24801982
24802307
24802768

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0007568  aging
GO:0031547  brain-derived neurotrophic factor receptor signaling pathway
GO:0021954  central nervous system neuron development
GO:0021987  cerebral cortex development
GO:0007631  feeding behavior
GO:0014047  glutamate secretion
GO:0007612  learning
GO:0007616  long-term memory
GO:0060291  long-term synaptic potentiation
GO:0042490  mechanoreceptor differentiation
GO:0043524  negative regulation of neuron apoptosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007528  neuromuscular junction development
GO:0030182  neuron differentiation
GO:0001764  neuron migration
GO:0048709  oligodendrocyte differentiation
GO:0048935  peripheral nervous system neuron development
GO:0050772  positive regulation of axonogenesis
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0043410  positive regulation of MAPKKK cascade
GO:0010976  positive regulation of neuron projection development
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0046777  protein amino acid autophosphorylation
GO:0050773  regulation of dendrite development
GO:0046928  regulation of neurotransmitter secretion
GO:0051896  regulation of protein kinase B signaling cascade
GO:0032314  regulation of Rac GTPase activity
GO:0010996  response to auditory stimulus
GO:0046548  retinal rod cell development
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001570  vasculogenesis

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0005829  cytosol
GO:0043197  dendritic spine
GO:0010008  endosome membrane
GO:0060076  excitatory synapse
GO:0030426  growth cone
GO:0005887  integral to plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0048786  presynaptic active zone
GO:0043195  terminal button

Molecular Function

GO:0005524  ATP binding
GO:0048403  brain-derived neurotrophic factor binding
GO:0060175  brain-derived neurotrophic factor receptor activity
GO:0046875  ephrin receptor binding
GO:0043121  neurotrophin binding
GO:0042803  protein homodimerization activity