neurotrophic tyrosine kinase, receptor, type 2

同義遺伝子名

NTRK2, BDNF/NT-3 growth factors receptor precursor, Trk-B, GP145-TrkB, TrkB tyrosine kinase, TRKB, neurotrophic tyrosine kinase, receptor, type 2, Neurotrophic tyrosine kinase receptor type 2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:403

小脳:239.30

脳幹:-

脳梁:175

松果体:148.30

末梢神経:153.40

脊柱:-

網膜:355.90

目:164.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:75.60

胸腺:25.80

骨髄:-

脂肪:40.30

骨:179.10

皮膚:72

GeneChip

nodata

CAGE

大脳:6.15

小脳:-

脳幹:5.56

脳梁:5.89

松果体:4.29

末梢神経:-

脊柱:5.92

網膜:-

目:-

動脈:3.56

静脈:3.63

リンパ節:2.13

末梢血:-

脾臓:2.19

胸腺:1.28

骨髄:-

脂肪:4.55

骨:-

皮膚:-

RNA-seq

大脳:1.85

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.16

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.07

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:82

胎盤:10.90

前立腺:33.80

卵巣:-

精巣:21.60

心臓:166

骨格筋:-

食道:-

胃:21.20

腸:32.40

結腸:50.90

肝臓:21.10

肺:68.40

膀胱:-

腎臓:31.20

下垂体:116

甲状腺:-

副腎:50.80

膵臓:35.60

乳腺:65.10

唾液腺:-

GeneChip

nodata

CAGE

子宮:3.07

胎盤:0.88

前立腺:2.50

卵巣:3.41

精巣:2.48

心臓:3.44

骨格筋:2.09

食道:2.76

胃:-

腸:1.27

結腸:1.96

肝臓:1.21

肺:1.76

膀胱:3.18

腎臓:3.48

下垂体:3.49

甲状腺:4.83

副腎:-

膵臓:3.90

乳腺:3.76

唾液腺:2.85

RNA-seq

子宮:-

胎盤:-

前立腺:0.09

卵巣:0.14

精巣:0.08

心臓:0.03

骨格筋:0

食道:-

胃:-

腸:-

結腸:0.07

肝臓:0.00

肺:0.12

膀胱:-

腎臓:0.28

下垂体:-

甲状腺:0.60

副腎:0.09

膵臓:-

乳腺:0.60

唾液腺:-

IDs

Refseq ID	NM_001018066
Gene ID	4915
Unigene ID	Hs.494312
Probe set ID	-
Ensembl ID	ENSG00000148053
GTEx ID	ENSG00000148053

オーソログ対応遺伝子

マウス[3]	NM_001025074, NM_008745
ラット[3]	NM_001163168, NM_001163169, NM_012731

染色体

9q21.33 [87,283,466 - 87,638,505]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020777	Tyrosine-protein kinase, neurotrophic receptor
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007568	aging
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway
GO:0021954	central nervous system neuron development
GO:0021987	cerebral cortex development
GO:0007631	feeding behavior
GO:0014047	glutamate secretion
GO:0007612	learning
GO:0007616	long-term memory
GO:0060291	long-term synaptic potentiation
GO:0042490	mechanoreceptor differentiation
GO:0043524	negative regulation of neuron apoptosis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0007528	neuromuscular junction development
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0048709	oligodendrocyte differentiation
GO:0048935	peripheral nervous system neuron development
GO:0050772	positive regulation of axonogenesis
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0043410	positive regulation of MAPKKK cascade
GO:0010976	positive regulation of neuron projection development
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0046777	protein amino acid autophosphorylation
GO:0050773	regulation of dendrite development
GO:0046928	regulation of neurotransmitter secretion
GO:0051896	regulation of protein kinase B signaling cascade
GO:0032314	regulation of Rac GTPase activity
GO:0010996	response to auditory stimulus
GO:0046548	retinal rod cell development
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001570	vasculogenesis

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0005829	cytosol
GO:0043197	dendritic spine
GO:0010008	endosome membrane
GO:0060076	excitatory synapse
GO:0030426	growth cone
GO:0005887	integral to plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0048786	presynaptic active zone
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0048403	brain-derived neurotrophic factor binding
GO:0060175	brain-derived neurotrophic factor receptor activity
GO:0046875	ephrin receptor binding
GO:0043121	neurotrophin binding
GO:0042803	protein homodimerization activity

neurotrophic tyrosine kinase, receptor, type 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function