neurotrophic tyrosine kinase, receptor, type 3

詳細情報を見る

同義遺伝子名

neurotrophic tyrosine kinase, receptor, type 3, gp145(trkC), TRKC, NTRK3, Neurotrophic tyrosine kinase receptor type 3, Trk-C, GP145-TrkC, NT-3 growth factor receptor precursor, TrkC tyrosine kinase

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.90 小脳:4.71 脳幹:4.78 脳梁:4.80 松果体:- 末梢神経:4.97 脊柱:4.98 網膜:- 目:- 動脈:5.32 静脈:5.07 リンパ節:4.20 末梢血:- 脾臓:4.14 胸腺:4.08 骨髄:4.70 脂肪:4.67 骨:- 皮膚:4.27
CAGE 大脳:4.79 小脳:- 脳幹:4.33 脳梁:3.97 松果体:3.91 末梢神経:- 脊柱:4.62 網膜:- 目:- 動脈:4.64 静脈:3.04 リンパ節:1.70 末梢血:- 脾臓:1.83 胸腺:1.12 骨髄:- 脂肪:3.03 骨:- 皮膚:-
RNA-seq 大脳:2.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.50 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.73 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.31 胎盤:4.46 前立腺:4.30 卵巣:3.96 精巣:5.27 心臓:4.70 骨格筋:4.56 食道:4.18 胃:4.41 腸:4.27 結腸:4.79 肝臓:4.15 肺:4.20 膀胱:- 腎臓:4.43 下垂体:4.39 甲状腺:3.97 副腎:4.48 膵臓:4.11 乳腺:4.08 唾液腺:4.69
CAGE 子宮:3.61 胎盤:0.85 前立腺:2.60 卵巣:3.02 精巣:2.93 心臓:2.86 骨格筋:1.48 食道:1.80 胃:- 腸:1.41 結腸:2.33     肝臓:0.90    肺:2.40 膀胱:2.87 腎臓:2.64 下垂体:3.19 甲状腺:1.52 副腎:- 膵臓:0 乳腺:3.12 唾液腺:2.35
RNA-seq 子宮:- 胎盤:- 前立腺:1.56 卵巣:0.78 精巣:2.41 心臓:0.47 骨格筋:0.27 食道:- 胃:- 腸:- 結腸:0.96     肝臓:0.12        肺:0.93    膀胱:- 腎臓:1.04 下垂体:- 甲状腺:0.65 副腎:1.68 膵臓:- 乳腺:1.38 唾液腺:-

IDs

Refseq ID NM_001007156
Gene ID 4916
Unigene ID -
Probe set ID 215025_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000140538
GTEx ID ENSG00000140538

オーソログ対応遺伝子

マウス[4]  NM_008746, NM_182809
ラット[1]  NM_019248, NM_182809

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0032148  activation of protein kinase B activity
GO:0032856  activation of Ras GTPase activity
GO:0071300  cellular response to retinoic acid
GO:0090102  cochlea development
GO:0042490  mechanoreceptor differentiation
GO:0019056  modulation by virus of host transcription
GO:0048712  negative regulation of astrocyte differentiation
GO:0060548  negative regulation of cell death
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0048665  neuron fate specification
GO:0001764  neuron migration
GO:0048691  positive regulation of axon extension involved in regeneration
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050927  positive regulation of positive chemotaxis
GO:0046777  protein amino acid autophosphorylation
GO:0048678  response to axon injury
GO:0051412  response to corticosterone stimulus
GO:0045471  response to ethanol
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0046875  ephrin receptor binding
GO:0043121  neurotrophin binding
GO:0005030  neurotrophin receptor activity
GO:0002039  p53 binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity