neurotrophic tyrosine kinase, receptor, type 3

同義遺伝子名

neurotrophic tyrosine kinase, receptor, type 3, gp145(trkC), TRKC, NTRK3, Neurotrophic tyrosine kinase receptor type 3, Trk-C, GP145-TrkC, NT-3 growth factor receptor precursor, TrkC tyrosine kinase

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:4.90

小脳:4.71

脳幹:4.78

脳梁:4.80

松果体:-

末梢神経:4.97

脊柱:4.98

網膜:-

目:-

動脈:5.32

静脈:5.07

リンパ節:4.20

末梢血:-

脾臓:4.14

胸腺:4.08

骨髄:4.70

脂肪:4.67

骨:-

皮膚:4.27

CAGE

大脳:4.79

小脳:-

脳幹:4.33

脳梁:3.97

松果体:3.91

末梢神経:-

脊柱:4.62

網膜:-

目:-

動脈:4.64

静脈:3.04

リンパ節:1.70

末梢血:-

脾臓:1.83

胸腺:1.12

骨髄:-

脂肪:3.03

骨:-

皮膚:-

RNA-seq

大脳:2.80

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.50

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.73

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:4.31

胎盤:4.46

前立腺:4.30

卵巣:3.96

精巣:5.27

心臓:4.70

骨格筋:4.56

食道:4.18

胃:4.41

腸:4.27

結腸:4.79

肝臓:4.15

肺:4.20

膀胱:-

腎臓:4.43

下垂体:4.39

甲状腺:3.97

副腎:4.48

膵臓:4.11

乳腺:4.08

唾液腺:4.69

CAGE

子宮:3.61

胎盤:0.85

前立腺:2.60

卵巣:3.02

精巣:2.93

心臓:2.86

骨格筋:1.48

食道:1.80

胃:-

腸:1.41

結腸:2.33

肝臓:0.90

肺:2.40

膀胱:2.87

腎臓:2.64

下垂体:3.19

甲状腺:1.52

副腎:-

膵臓:0

乳腺:3.12

唾液腺:2.35

RNA-seq

子宮:-

胎盤:-

前立腺:1.56

卵巣:0.78

精巣:2.41

心臓:0.47

骨格筋:0.27

食道:-

胃:-

腸:-

結腸:0.96

肝臓:0.12

肺:0.93

膀胱:-

腎臓:1.04

下垂体:-

甲状腺:0.65

副腎:1.68

膵臓:-

乳腺:1.38

唾液腺:-

IDs

Refseq ID	NM_001007156
Gene ID	4916
Unigene ID	-
Probe set ID	215025_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140538
GTEx ID	ENSG00000140538

オーソログ対応遺伝子

マウス[4]	NM_008746, NM_182809
ラット[1]	NM_019248, NM_182809

染色体

15q25.3 [88,402,982 - 88,799,978]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020777	Tyrosine-protein kinase, neurotrophic receptor
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0032148	activation of protein kinase B activity
GO:0032856	activation of Ras GTPase activity
GO:0071300	cellular response to retinoic acid
GO:0090102	cochlea development
GO:0042490	mechanoreceptor differentiation
GO:0019056	modulation by virus of host transcription
GO:0048712	negative regulation of astrocyte differentiation
GO:0060548	negative regulation of cell death
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0048665	neuron fate specification
GO:0001764	neuron migration
GO:0048691	positive regulation of axon extension involved in regeneration
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0050927	positive regulation of positive chemotaxis
GO:0046777	protein amino acid autophosphorylation
GO:0048678	response to axon injury
GO:0051412	response to corticosterone stimulus
GO:0045471	response to ethanol
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005887	integral to plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0046875	ephrin receptor binding
GO:0043121	neurotrophin binding
GO:0005030	neurotrophin receptor activity
GO:0002039	p53 binding
GO:0004714	transmembrane receptor protein tyrosine kinase activity

neurotrophic tyrosine kinase, receptor, type 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function