purinergic receptor P2X, ligand-gated ion channel, 7

詳細情報を見る

同義遺伝子名

P2Z receptor, P2X purinoceptor 7, P2X7, MGC20089, P2RX7

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:93.60

小脳:25.20

脳幹:-

脳梁:379.10

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:5.90

動脈:-

静脈:-

リンパ節:10.10

末梢血:200.40

脾臓:189.10

胸腺:25.80

骨髄:19.70

脂肪:40.30

骨:230.30

皮膚:38.40

GeneChip

大脳:6.55

小脳:4.96

脳幹:6.19

脳梁:7.87

松果体:-

末梢神経:5.83

脊柱:6.77

網膜:-

目:-

動脈:4.70

静脈:4.52

リンパ節:5.01

末梢血:-

脾臓:5.34

胸腺:4.72

骨髄:4.54

脂肪:4.80

骨:-

皮膚:5.32

CAGE

大脳:2.96

小脳:-

脳幹:3.64

脳梁:3.97

松果体:1.17

末梢神経:-

脊柱:3.41

網膜:-

目:-

動脈:0.59

静脈:0.88

リンパ節:1.06

末梢血:-

脾臓:1.02

胸腺:0.83

骨髄:-

脂肪:1.41

骨:-

皮膚:-

RNA-seq

大脳:2.36

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.00

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.15

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:45.60

胎盤:21.90

前立腺:11.30

卵巣:-

精巣:-

心臓:-

骨格筋:20.10

食道:-

胃:21.20

腸:64.80

結腸:-

肝臓:10.60

肺:24.40

膀胱:125.60

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:18.60

唾液腺:-

GeneChip

子宮:4.75

胎盤:4.42

前立腺:4.60

卵巣:4.96

精巣:4.51

心臓:4.35

骨格筋:4.41

食道:4.99

胃:4.39

腸:4.62

結腸:4.48

肝臓:4.84

肺:5.17

膀胱:-

腎臓:4.36

下垂体:4.81

甲状腺:4.45

副腎:4.69

膵臓:5.06

乳腺:5.16

唾液腺:4.77

CAGE

子宮:1.55

胎盤:0.54

前立腺:1.28

卵巣:1.16

精巣:0.77

心臓:0.28

骨格筋:0.27

食道:0.73

胃:-

腸:0.53

結腸:0.75

肝臓:0.90

肺:1.27

膀胱:1.24

腎臓:0.15

下垂体:0.62

甲状腺:0.41

副腎:-

膵臓:0.58

乳腺:0.55

唾液腺:1.00

RNA-seq

子宮:-

胎盤:-

前立腺:1.24

卵巣:1.12

精巣:0.14

心臓:0.00

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.59

肝臓:0

肺:0.00

膀胱:-

腎臓:0.00

下垂体:-

甲状腺:0.00

副腎:0.13

膵臓:-

乳腺:0.61

唾液腺:-

IDs

Refseq ID	NM_002562
Gene ID	5027
Unigene ID	Hs.507102
Probe set ID	207091_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000089041
GTEx ID	ENSG00000089041

オーソログ対応遺伝子

マウス[4]	NM_001038839, NM_001038845, NM_001038887, NM_011027
ラット [0]

染色体

12q24.31 [121,570,622 - 121,623,876]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001429	P2X purinoreceptor
IPR003050	P2X7 purinoceptor

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0032060	bleb formation
GO:0000902	cell morphogenesis
GO:0007166	cell surface receptor linked signal transduction
GO:0006884	cell volume homeostasis
GO:0031668	cellular response to extracellular stimulus
GO:0046513	ceramide biosynthetic process
GO:0032963	collagen metabolic process
GO:0019835	cytolysis
GO:0050830	defense response to Gram-positive bacterium
GO:0048873	homeostasis of number of cells within a tissue
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0006900	membrane budding
GO:0051899	membrane depolarization
GO:0006509	membrane protein ectodomain proteolysis
GO:0007005	mitochondrion organization
GO:0044254	multicellular organismal protein catabolic process
GO:0043132	NAD transport
GO:0045779	negative regulation of bone resorption
GO:0043409	negative regulation of MAPKKK cascade
GO:0001845	phagolysosome formation
GO:0006649	phospholipid transfer to membrane
GO:0045332	phospholipid translocation
GO:0007009	plasma membrane organization
GO:0046931	pore complex assembly
GO:0043065	positive regulation of apoptosis
GO:0030501	positive regulation of bone mineralization
GO:0010524	positive regulation of calcium ion transport into cytosol
GO:0045919	positive regulation of cytolysis
GO:0051495	positive regulation of cytoskeleton organization
GO:0014054	positive regulation of gamma-aminobutyric acid secretion
GO:0014049	positive regulation of glutamate secretion
GO:0050717	positive regulation of interleukin-1 alpha secretion
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0032755	positive regulation of interleukin-6 production
GO:0051901	positive regulation of mitochondrial depolarization
GO:0032308	positive regulation of prostaglandin secretion
GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0006468	protein amino acid phosphorylation
GO:0051259	protein oligomerization
GO:0016485	protein processing
GO:0019228	regulation of action potential in neuron
GO:0051709	regulation of killing of cells of another organism
GO:0002028	regulation of sodium ion transport
GO:0051209	release of sequestered calcium ion into cytosol
GO:0033198	response to ATP
GO:0051592	response to calcium ion
GO:0042493	response to drug
GO:0051602	response to electrical stimulus
GO:0034405	response to fluid shear stress
GO:0032496	response to lipopolysaccharide
GO:0009612	response to mechanical stimulus
GO:0010043	response to zinc ion
GO:0019233	sensory perception of pain
GO:0048705	skeletal system morphogenesis
GO:0016079	synaptic vesicle exocytosis
GO:0043029	T cell homeostasis
GO:0042098	T cell proliferation

Cellular Component

GO:0032059	bleb
GO:0043025	cell soma
GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0009897	external side of plasma membrane
GO:0005639	integral to nuclear inner membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0031594	neuromuscular junction
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0004931	ATP-gated cation channel activity
GO:0005507	copper ion binding
GO:0001530	lipopolysaccharide binding
GO:0000287	magnesium ion binding
GO:0042803	protein homodimerization activity
GO:0001614	purinergic nucleotide receptor activity
GO:0005102	receptor binding
GO:0008270	zinc ion binding

purinergic receptor P2X, ligand-gated ion channel, 7

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function