lymphoid enhancer-binding factor 1

詳細情報を見る

同義遺伝子名

LEF1, LEF-1, lymphoid enhancer-binding factor 1, TCF1ALPHA, TCF1-alpha, T cell-specific transcription factor 1-alpha, Lymphoid enhancer-binding factor 1, DKFZp586H0919

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:3.51 小脳:3.25 脳幹:3.33 脳梁:3.41 松果体:- 末梢神経:3.84 脊柱:3.39 網膜:- 目:- 動脈:3.30 静脈:3.29 リンパ節:4.52 末梢血:- 脾臓:3.94 胸腺:9.07 骨髄:3.90 脂肪:3.46 骨:- 皮膚:3.26
CAGE 大脳:1.85 小脳:- 脳幹:2.14 脳梁:2.35 松果体:2.00 末梢神経:- 脊柱:1.88 網膜:- 目:- 動脈:1.57 静脈:4.83 リンパ節:4.18 末梢血:- 脾臓:2.83 胸腺:6.71 骨髄:- 脂肪:1.21 骨:- 皮膚:-
RNA-seq 大脳:0.17 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.07 骨:- 皮膚:-
EST nodata
GeneChip 子宮:3.89 胎盤:3.61 前立腺:3.29 卵巣:3.51 精巣:3.93 心臓:3.35 骨格筋:3.25 食道:3.33 胃:3.35 腸:3.49 結腸:3.40 肝臓:3.43 肺:3.42 膀胱:- 腎臓:3.42 下垂体:3.24 甲状腺:3.39 副腎:4.12 膵臓:3.42 乳腺:3.62 唾液腺:3.27
CAGE 子宮:2.52 胎盤:1.86 前立腺:1.91 卵巣:1.87 精巣:2.95 心臓:0.70 骨格筋:0.49 食道:2.01 胃:- 腸:1.52 結腸:1.21     肝臓:0    肺:2.19 膀胱:1.76 腎臓:1.86 下垂体:1.11 甲状腺:2.16 副腎:- 膵臓:1.21 乳腺:2.02 唾液腺:1.58
RNA-seq 子宮:- 胎盤:- 前立腺:0.18 卵巣:0.00 精巣:0.00 心臓:0.00 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.00        肺:0.62    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.32 副腎:0.00 膵臓:- 乳腺:0.08 唾液腺:-

IDs

Refseq ID NM_001130713
Gene ID 51176
Unigene ID -
Probe set ID 210948_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138795
GTEx ID ENSG00000138795

オーソログ対応遺伝子

マウス[1]  NM_010703
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0046632  alpha-beta T cell differentiation
GO:0060033  anatomical structure regression
GO:0060561  apoptosis involved in morphogenesis
GO:0042100  B cell proliferation
GO:0030509  BMP signaling pathway
GO:0007420  brain development
GO:0060326  cell chemotaxis
GO:0071345  cellular response to cytokine stimulus
GO:0071353  cellular response to interleukin-4
GO:0060710  chorio-allantoic fusion
GO:0021542  dentate gyrus development
GO:0030326  embryonic limb morphogenesis
GO:0001837  epithelial to mesenchymal transition
GO:0048069  eye pigmentation
GO:0060325  face morphogenesis
GO:0021873  forebrain neuroblast division
GO:0021879  forebrain neuron differentiation
GO:0021943  formation of radial glial scaffolds
GO:0048699  generation of neurons
GO:0043966  histone H3 acetylation
GO:0043967  histone H4 acetylation
GO:0021854  hypothalamus development
GO:0006917  induction of apoptosis
GO:0030879  mammary gland development
GO:0048747  muscle fiber development
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0022408  negative regulation of cell-cell adhesion
GO:0043392  negative regulation of DNA binding
GO:0032696  negative regulation of interleukin-13 production
GO:0032713  negative regulation of interleukin-4 production
GO:0032714  negative regulation of interleukin-5 production
GO:0045843  negative regulation of striated muscle tissue development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001755  neural crest cell migration
GO:0022008  neurogenesis
GO:0030223  neutrophil differentiation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0001649  osteoblast differentiation
GO:0060021  palate development
GO:0048341  paraxial mesoderm formation
GO:0001569  patterning of blood vessels
GO:0043923  positive regulation by host of viral transcription
GO:0090068  positive regulation of cell cycle process
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0022409  positive regulation of cell-cell adhesion
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0010628  positive regulation of gene expression
GO:0030854  positive regulation of granulocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0021861  radial glial cell differentiation in the forebrain
GO:0022407  regulation of cell-cell adhesion
GO:0016202  regulation of striated muscle tissue development
GO:0050909  sensory perception of taste
GO:0001756  somitogenesis
GO:0002040  sprouting angiogenesis
GO:0033153  T cell receptor V(D)J recombination
GO:0045063  T-helper 1 cell differentiation
GO:0043586  tongue development
GO:0006366  transcription from RNA polymerase II promoter
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0032993  protein-DNA complex
GO:0005667  transcription factor complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0008013  beta-catenin binding
GO:0070742  C2H2 zinc finger domain binding
GO:0043027  caspase inhibitor activity
GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0030284  estrogen receptor activity
GO:0030331  estrogen receptor binding
GO:0045295  gamma-catenin binding
GO:0042393  histone binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding