toll-like receptor 7

詳細情報を見る

同義遺伝子名

UNQ248/PRO285, Toll-like receptor 7 precursor, TLR7, toll-like receptor 7

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:3.44 小脳:3.08 脳幹:3.54 脳梁:3.92 松果体:- 末梢神経:3.69 脊柱:4.19 網膜:- 目:- 動脈:3.34 静脈:3.21 リンパ節:3.97 末梢血:- 脾臓:3.95 胸腺:3.70 骨髄:3.20 脂肪:3.34 骨:- 皮膚:3.14
CAGE 大脳:2.49 小脳:- 脳幹:3.42 脳梁:3.36 松果体:1.70 末梢神経:- 脊柱:4.00 網膜:- 目:- 動脈:1.75 静脈:2.60 リンパ節:2.55 末梢血:- 脾臓:2.88 胸腺:2.88 骨髄:- 脂肪:1.86 骨:- 皮膚:-
RNA-seq 大脳:1.22 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.41 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.14 骨:- 皮膚:-
EST nodata
GeneChip 子宮:3.26 胎盤:3.49 前立腺:3.23 卵巣:3.26 精巣:2.95 心臓:3.09 骨格筋:3.20 食道:3.07 胃:3.21 腸:3.13 結腸:3.07 肝臓:3.21 肺:3.68 膀胱:- 腎臓:3.09 下垂体:3.26 甲状腺:3.20 副腎:3.48 膵臓:3.01 乳腺:3.58 唾液腺:3.34
CAGE 子宮:1.52 胎盤:2.87 前立腺:2.10 卵巣:1.65 精巣:0.83 心臓:0.96 骨格筋:0.63 食道:1.26 胃:- 腸:1.97 結腸:0.88     肝臓:0.78    肺:2.55 膀胱:1.24 腎臓:1.37 下垂体:1.27 甲状腺:0.79 副腎:- 膵臓:0.94 乳腺:1.68 唾液腺:2.26
RNA-seq 子宮:- 胎盤:- 前立腺:0.72 卵巣:0.68 精巣:0.40 心臓:0.37 骨格筋:0.04 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.05        肺:0.25    膀胱:- 腎臓:0.17 下垂体:- 甲状腺:0.13 副腎:1.41 膵臓:- 乳腺:0.56 唾液腺:-

IDs

Refseq ID NM_016562
Gene ID 51284
Unigene ID -
Probe set ID 220146_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196664
GTEx ID ENSG00000196664

オーソログ対応遺伝子

マウス[1]  NM_133211
ラット[1]  NM_001097582

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0071260  cellular response to mechanical stimulus
GO:0051607  defense response to virus
GO:0007252  I-kappaB phosphorylation
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0002282  microglial cell activation during immune response
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0052033  pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0032722  positive regulation of chemokine production
GO:0050729  positive regulation of inflammatory response
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032755  positive regulation of interleukin-6 production
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0032757  positive regulation of interleukin-8 production
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0042221  response to chemical stimulus
GO:0034154  toll-like receptor 7 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0032009  early phagosome
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005768  endosome
GO:0010008  endosome membrane
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0005886  plasma membrane

Molecular Function

GO:0003725  double-stranded RNA binding
GO:0008144  drug binding
GO:0003727  single-stranded RNA binding
GO:0035197  siRNA binding
GO:0004888  transmembrane receptor activity