platelet-derived growth factor alpha polypeptide

同義遺伝子名

PDGF-A, platelet-derived growth factor alpha polypeptide, PDGFA, Platelet-derived growth factor alpha polypeptide, Platelet-derived growth factor A chain precursor, PDGF1, PDGF-1, PDGF A-chain

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:224.60

網膜:118.60

目:17.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:9.60

GeneChip

大脳:5.60

小脳:4.81

脳幹:5.73

脳梁:5.98

松果体:-

末梢神経:5.39

脊柱:5.81

網膜:-

目:-

動脈:6.48

静脈:5.96

リンパ節:5.10

末梢血:-

脾臓:5.39

胸腺:4.70

骨髄:4.61

脂肪:5.07

骨:-

皮膚:5.15

CAGE

大脳:3.77

小脳:-

脳幹:4.31

脳梁:4.66

松果体:3.11

末梢神経:-

脊柱:4.46

網膜:-

目:-

動脈:5.19

静脈:3.32

リンパ節:2.86

末梢血:-

脾臓:3.59

胸腺:1.93

骨髄:-

脂肪:2.93

骨:-

皮膚:-

RNA-seq

大脳:3.77

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.46

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.41

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:3.60

前立腺:11.30

卵巣:-

精巣:8.70

心臓:25.50

骨格筋:-

食道:-

胃:-

腸:-

結腸:17

肝臓:10.60

肺:9.80

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:-

膵臓:8.90

乳腺:9.30

唾液腺:-

GeneChip

子宮:5.04

胎盤:4.87

前立腺:6.16

卵巣:4.89

精巣:4.77

心臓:5.39

骨格筋:5.39

食道:5.14

胃:6.03

腸:5.34

結腸:5.08

肝臓:4.82

肺:5.57

膀胱:-

腎臓:5.80

下垂体:5.24

甲状腺:5.17

副腎:5.33

膵臓:6.02

乳腺:5.52

唾液腺:6.19

CAGE

子宮:3.61

胎盤:3.20

前立腺:3.52

卵巣:3.14

精巣:2.56

心臓:3.69

骨格筋:2.46

食道:3.37

胃:-

腸:3.84

結腸:3.84

肝臓:2.82

肺:3.91

膀胱:3.56

腎臓:3.18

下垂体:2.30

甲状腺:2.64

副腎:-

膵臓:4.13

乳腺:4.04

唾液腺:3.80

RNA-seq

子宮:-

胎盤:-

前立腺:2.84

卵巣:2.62

精巣:2.95

心臓:1.70

骨格筋:2.55

食道:-

胃:-

腸:-

結腸:3.17

肝臓:0.78

肺:4.01

膀胱:-

腎臓:2.14

下垂体:-

甲状腺:2.38

副腎:3.55

膵臓:-

乳腺:2.96

唾液腺:-

IDs

Refseq ID	NM_033023
Gene ID	5154
Unigene ID	Hs.535898
Probe set ID	216867_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000197461
GTEx ID	ENSG00000197461

オーソログ対応遺伝子

マウス[2]	NM_008808
ラット [0]

染色体

7p22.3 [536,895 - 559,933]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0001525	angiogenesis
GO:0007596	blood coagulation
GO:0001775	cell activation
GO:0030031	cell projection assembly
GO:0007267	cell-cell signaling
GO:0009790	embryonic development
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0030198	extracellular matrix organization
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0001942	hair follicle development
GO:0045087	innate immune response
GO:0048839	inner ear development
GO:0048286	lung alveolus development
GO:0050919	negative chemotaxis
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
GO:0010544	negative regulation of platelet activation
GO:0048011	nerve growth factor receptor signaling pathway
GO:0009887	organ morphogenesis
GO:0048015	phosphoinositide-mediated signaling
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0051781	positive regulation of cell division
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0045740	positive regulation of DNA replication
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0048146	positive regulation of fibroblast proliferation
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0031954	positive regulation of protein amino acid autophosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0032956	regulation of actin cytoskeleton organization
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
GO:0050730	regulation of peptidyl-tyrosine phosphorylation
GO:0014910	regulation of smooth muscle cell migration
GO:0042493	response to drug
GO:0032355	response to estradiol stimulus
GO:0001666	response to hypoxia
GO:0010035	response to inorganic substance
GO:0032526	response to retinoic acid
GO:0009611	response to wounding
GO:0043588	skin development
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0042060	wound healing

Cellular Component

GO:0009986	cell surface
GO:0005788	endoplasmic reticulum lumen
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0000139	Golgi membrane
GO:0005902	microvillus
GO:0031093	platelet alpha granule lumen

Molecular Function

GO:0005518	collagen binding
GO:0008083	growth factor activity
GO:0048407	platelet-derived growth factor binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity

platelet-derived growth factor alpha polypeptide

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function