platelet-derived growth factor receptor, alpha polypeptide

詳細情報を見る

同義遺伝子名

PDGFR2, PDGF-R-alpha, CD140A, CD140a antigen, CD140a, PDGFRA, MGC74795

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:53.30 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:306.70 脊柱:112.30 網膜:- 目:82.30 動脈:149.90 静脈:- リンパ節:10.10 末梢血:- 脾臓:113.40 胸腺:38.70 骨髄:39.40 脂肪:121 骨:115.20 皮膚:-
GeneChip 大脳:7.10 小脳:5.41 脳幹:7.10 脳梁:7.42 松果体:- 末梢神経:7.82 脊柱:7.53 網膜:- 目:- 動脈:8.71 静脈:8.16 リンパ節:7.18 末梢血:- 脾臓:9.30 胸腺:6.39 骨髄:5.26 脂肪:8.75 骨:- 皮膚:8.21
CAGE 大脳:3.10 小脳:- 脳幹:3.52 脳梁:3.60 松果体:3.07 末梢神経:- 脊柱:3.80 網膜:- 目:- 動脈:4.20 静脈:3.66 リンパ節:3.76 末梢血:- 脾臓:5.23 胸腺:1.49 骨髄:- 脂肪:4.90 骨:- 皮膚:-
RNA-seq 大脳:2.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:5.69 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.73 骨:- 皮膚:-
EST 子宮:200.50 胎盤:69.20 前立腺:45.10 卵巣:335.40 精巣:43.30 心臓:153.30 骨格筋:40.20 食道:- 胃:- 腸:64.80 結腸:25.40     肝臓:42.20        肺:88    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:27.90 唾液腺:-
GeneChip 子宮:9.39 胎盤:7.45 前立腺:7.89 卵巣:9.70 精巣:7.21 心臓:8.35 骨格筋:7.33 食道:7.53 胃:9.14 腸:8.65 結腸:8.34 肝臓:6.94 肺:8.66 膀胱:- 腎臓:6.71 下垂体:5.24 甲状腺:7.10 副腎:9.25 膵臓:7.27 乳腺:8.49 唾液腺:6.41
CAGE 子宮:4.78 胎盤:3.84 前立腺:4.30 卵巣:5.36 精巣:3.89 心臓:4.01 骨格筋:3.11 食道:4.41 胃:- 腸:4.18 結腸:4.05     肝臓:3.39    肺:4.12 膀胱:4.89 腎臓:4.41 下垂体:2.02 甲状腺:3.71 副腎:- 膵臓:2.94 乳腺:4.20 唾液腺:2.88
RNA-seq 子宮:- 胎盤:- 前立腺:4.87 卵巣:5.93 精巣:5.14 心臓:3.31 骨格筋:2.14 食道:- 胃:- 腸:- 結腸:5.64     肝臓:2.92        肺:4.30    膀胱:- 腎臓:4.90 下垂体:- 甲状腺:4.08 副腎:3.92 膵臓:- 乳腺:3.77 唾液腺:-

IDs

Refseq ID NM_006206
Gene ID 5156
Unigene ID Hs.74615
Probe set ID 203131_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134853
GTEx ID ENSG00000134853

オーソログ対応遺伝子

マウス[4]  NM_001083316, NM_011058
ラット[3]  NM_012802, NM_011058

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1646396
1711435
1847074
2161888
2531695
2536956
2542288
2544881
2554309
7519254
7523122
7535778
7665222
7896447
8188664
8261442
8486649
8586421
8617789
8647855
8647858
8702949
8774134
8894141
8943348
9234717
9484840
9546424
9739761
9819414
10066366
10508235
10733900
10734113
10806482
10837138
11046132
11095946
11175793
11279102
11297552
11342471
11468294
11752456
11776032
11882663
11953315
12023424
12119411
12176024
12477932
12522257
12660384
12808148
12842979
14630792
14741194
14745431
14766209
15154005
15284118
15326474
15380338
15489334
15492989
15635072
15674355
15685537
15717329
15791568
15862965
15871904
15894928
15897742
15928335
16116920
16126374
16135486
16168125
16186508
16283668
16305343
16331269
16344560
16357008
16373964
16498388
16502585
16675559
16685437
16690743
16697720
16730575
16785193
16804324
16850112
16892550
17047316
17070723
17079230
17137731
17145809
17193822
17214097
17261495
17298867
17299092
17344284
17363728
17377585
17438095
17448020
17452978
17470632
17532173
17566086
17568391
17591942
17623951
17673922
17690840
17701174
17762857
17827398
17881156
18042065
18070887
18077793
18084259
18157090
18187489
18190445
18193045
18197502
18265649
18284546
18288404
18312355
18314611
18326546
18331602
18360281
18416137
18464291
18492696
18519768
18547963
18548106
18615679
18618605
18633616
18636362
18679424
18686281
18701889
18706197
18758297
18950958
18955458
18978678
18987651
18992915
19035305
19047372
19074885
19115205
19118897
19126548
19212337
19215021
19248967
19291337
19302534
19307738
19326424
19333543
19333919
19333949
19335066
19351817
19393245
19411681
19448595
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19563658
19614767
19644140
19648886
19649203
19675092
19694830
19696981
19707201
19717644
19755855
19756614
19779861
19787330
19839721
19843560
19846951
19861461
19862822
19900103
19913121
19936766
19943934
19946888
19953087
19956635
20001342
20023271
20036812
20071345
20107158
20129251
20133985
20139978
20169295
20379614
20393746
20424473
20425130
20442296
20453000
20470368
20473908
20479398
20485444
20589679
20598160
20615084
20628086
20634891
20651400
20686603
20718716
20800603
20823768
20861712
20889717
21080877
21092857
21131919
21157293
21210262
21224473
21274753
21281241
21310211
21357737
21382095
21387320
21396851
21397860
21399396
21403518
21434524
21461555
21478825
21496277
21527588
21574155
21590454
21596750
21605429
21642621
21645144
21665993
21725412
21769672
21818111
21819482
21947029
21953054
21988832
21993628
22076173
22080864
22137795
22144915
22160160
22237707
22293178
22311673
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22389665
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23146028
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23292839
23391309
23401653
23411580
23438035
23567961
23577108
23602568
23618877
23620752
23621172
23621836
23630597
23671131
23696920
23696935
23755839
23761726
23776077
23833305
23914042
23928059
23940030
23970477
23990986
24040448
24151977
24157063
24190966
24369323
24458279
24550449

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0055003  cardiac myofibril assembly
GO:0001775  cell activation
GO:0060326  cell chemotaxis
GO:0071230  cellular response to amino acid stimulus
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0048557  embryonic digestive tract morphogenesis
GO:0048704  embryonic skeletal system morphogenesis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008210  estrogen metabolic process
GO:0030198  extracellular matrix organization
GO:0060325  face morphogenesis
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0033327  Leydig cell differentiation
GO:0030324  lung development
GO:0001553  luteinization
GO:0030539  male genitalia development
GO:0010544  negative regulation of platelet activation
GO:0048011  nerve growth factor receptor signaling pathway
GO:0042475  odontogenesis of dentine-containing tooth
GO:0060021  palate development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0070527  platelet aggregation
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0010863  positive regulation of phospholipase C activity
GO:0046777  protein amino acid autophosphorylation
GO:0050920  regulation of chemotaxis
GO:0048010  vascular endothelial growth factor receptor signaling pathway
GO:0019048  virus-host interaction
GO:0042060  wound healing

Cellular Component

GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0005887  integral to plasma membrane
GO:0031226  intrinsic to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005018  platelet-derived growth factor alpha-receptor activity
GO:0048407  platelet-derived growth factor binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005021  vascular endothelial growth factor receptor activity