3-phosphoinositide dependent protein kinase-1

同義遺伝子名

MGC20087, 3-phosphoinositide-dependent protein kinase 1, 3-phosphoinositide dependent protein kinase-1, PkB kinase, PkB-like 1, MGC35290, PDPK1, PDK1, PRO0461, PkB-like, hPDK1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:96

小脳:163.70

脳幹:-

脳梁:87.50

松果体:-

末梢神経:30.70

脊柱:-

網膜:118.60

目:123.40

動脈:-

静脈:-

リンパ節:131.40

末梢血:91.10

脾臓:37.80

胸腺:103.10

骨髄:118.10

脂肪:40.30

骨:51.20

皮膚:100.80

GeneChip

大脳:8.38

小脳:8.45

脳幹:8.34

脳梁:8.30

松果体:-

末梢神経:8.31

脊柱:8.26

網膜:-

目:-

動脈:8.15

静脈:8.42

リンパ節:8.26

末梢血:-

脾臓:8.43

胸腺:8

骨髄:8.32

脂肪:8.23

骨:-

皮膚:8.18

CAGE

大脳:3.43

小脳:-

脳幹:2.97

脳梁:3.14

松果体:3.36

末梢神経:-

脊柱:2.87

網膜:-

目:-

動脈:2.98

静脈:2.75

リンパ節:3.00

末梢血:-

脾臓:2.73

胸腺:2.95

骨髄:-

脂肪:2.60

骨:-

皮膚:-

RNA-seq

大脳:2.64

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.39

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.85

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:91.10

胎盤:80.10

前立腺:67.60

卵巣:37.30

精巣:151.40

心臓:51.10

骨格筋:40.20

食道:-

胃:106.20

腸:32.40

結腸:195

肝臓:105.60

肺:73.30

膀胱:-

腎臓:114.40

下垂体:116

甲状腺:-

副腎:-

膵臓:97.80

乳腺:46.50

唾液腺:-

GeneChip

子宮:8.12

胎盤:8.25

前立腺:7.95

卵巣:8.11

精巣:8.17

心臓:8.31

骨格筋:8.16

食道:8.32

胃:8.39

腸:8.28

結腸:8.48

肝臓:8.44

肺:8.34

膀胱:-

腎臓:8.47

下垂体:8.32

甲状腺:8.26

副腎:8.42

膵臓:8.43

乳腺:8.19

唾液腺:8.52

CAGE

子宮:2.88

胎盤:3.18

前立腺:2.82

卵巣:2.55

精巣:2.88

心臓:2.74

骨格筋:2.92

食道:2.70

胃:-

腸:3.20

結腸:3.05

肝臓:2.84

肺:2.94

膀胱:2.75

腎臓:2.93

下垂体:2.95

甲状腺:2.98

副腎:-

膵臓:3.65

乳腺:3.12

唾液腺:3.17

RNA-seq

子宮:-

胎盤:-

前立腺:2.44

卵巣:2.74

精巣:2.77

心臓:2.60

骨格筋:2.60

食道:-

胃:-

腸:-

結腸:1.96

肝臓:1.62

肺:1.96

膀胱:-

腎臓:2.58

下垂体:-

甲状腺:2.21

副腎:1.87

膵臓:-

乳腺:1.90

唾液腺:-

IDs

Refseq ID	NM_002613
Gene ID	5170
Unigene ID	Hs.459691
Probe set ID	32029_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140992
GTEx ID	ENSG00000140992

オーソログ対応遺伝子

マウス[3]	NM_001080773, NM_011062
ラット [0]

染色体

16p13.3 [2,587,965 - 2,653,189]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0032148	activation of protein kinase B activity
GO:0007596	blood coagulation
GO:0032869	cellular response to insulin stimulus
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0048041	focal adhesion formation
GO:0006972	hyperosmotic response
GO:0045087	innate immune response
GO:0008286	insulin receptor signaling pathway
GO:0010667	negative regulation of cardiac muscle cell apoptosis
GO:0006469	negative regulation of protein kinase activity
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0048011	nerve growth factor receptor signaling pathway
GO:0003323	pancreatic B cell development
GO:0018107	peptidyl-threonine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0030168	platelet activation
GO:0090004	positive regulation of establishment of protein localization in plasma membrane
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0010594	regulation of endothelial cell migration
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043304	regulation of mast cell degranulation
GO:0006355	regulation of transcription, DNA-dependent
GO:0007268	synaptic transmission
GO:0031295	T cell costimulation
GO:0050852	T cell receptor signaling pathway
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0005654	nucleoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0004676	3-phosphoinositide-dependent protein kinase activity
GO:0005524	ATP binding
GO:0005158	insulin receptor binding
GO:0016301	kinase activity
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity

3-phosphoinositide dependent protein kinase-1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function