serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

詳細情報を見る

同義遺伝子名

nexin, SERPINE2, GDN, Protease inhibitor 7, Protease nexin I, PNI, Glia-derived nexin precursor, PN1, PN-1, PI7

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:132.70 小脳:50.40 脳幹:- 脳梁:29.20 松果体:- 末梢神経:122.70 脊柱:224.60 網膜:- 目:47 動脈:60 静脈:- リンパ節:- 末梢血:18.20 脾臓:18.90 胸腺:64.40 骨髄:196.80 脂肪:- 骨:345.50 皮膚:96
GeneChip 大脳:9.33 小脳:8.62 脳幹:9.23 脳梁:9.17 松果体:- 末梢神経:9.87 脊柱:9.84 網膜:- 目:- 動脈:7.95 静脈:8 リンパ節:7.36 末梢血:- 脾臓:7.98 胸腺:6.77 骨髄:5.85 脂肪:6.76 骨:- 皮膚:6.93
CAGE 大脳:4.74 小脳:- 脳幹:4.52 脳梁:4.51 松果体:2.86 末梢神経:- 脊柱:5.07 網膜:- 目:- 動脈:3.91 静脈:3.18 リンパ節:3.29 末梢血:- 脾臓:3.33 胸腺:2.66 骨髄:- 脂肪:2.86 骨:- 皮膚:-
RNA-seq 大脳:5.89 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.74 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.18 骨:- 皮膚:-
EST 子宮:145.80 胎盤:364.30 前立腺:11.30 卵巣:37.30 精巣:99.50 心臓:89.40 骨格筋:20.10 食道:342.80 胃:21.20 腸:32.40 結腸:50.90     肝臓:21.10        肺:29.30    膀胱:- 腎臓:135.20 下垂体:- 甲状腺:- 副腎:50.80 膵臓:26.70 乳腺:46.50 唾液腺:-
GeneChip 子宮:7.19 胎盤:11.44 前立腺:6.46 卵巣:8.46 精巣:8.96 心臓:7.92 骨格筋:5.79 食道:7.57 胃:7.37 腸:7.98 結腸:7.28 肝臓:6.01 肺:6.44 膀胱:- 腎臓:8 下垂体:6.74 甲状腺:7.70 副腎:6.71 膵臓:6.75 乳腺:7.37 唾液腺:5.76
CAGE 子宮:3.27 胎盤:6.73 前立腺:3.29 卵巣:4.74 精巣:4.28 心臓:4.90 骨格筋:1.63 食道:4.15 胃:- 腸:3.31 結腸:2.82     肝臓:1.95    肺:2.22 膀胱:4.45 腎臓:3.89 下垂体:1.74 甲状腺:3.09 副腎:- 膵臓:2.34 乳腺:3.78 唾液腺:1.58
RNA-seq 子宮:- 胎盤:- 前立腺:2.65 卵巣:6.77 精巣:5.77 心臓:1.34 骨格筋:0 食道:- 胃:- 腸:- 結腸:4.40     肝臓:1.00        肺:1.45    膀胱:- 腎臓:4.28 下垂体:- 甲状腺:3.76 副腎:4.16 膵臓:- 乳腺:2.08 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0021683  cerebellar granular layer morphogenesis
GO:0050974  detection of mechanical stimulus involved in sensory perception
GO:0060384  innervation
GO:0060291  long-term synaptic potentiation
GO:0042628  mating plug formation
GO:0030195  negative regulation of blood coagulation
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010951  negative regulation of endopeptidase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0010757  negative regulation of plasminogen activation
GO:0010544  negative regulation of platelet activation
GO:0042177  negative regulation of protein catabolic process
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0045861  negative regulation of proteolysis
GO:0045879  negative regulation of smoothened signaling pathway
GO:0010766  negative regulation of sodium ion transport
GO:0048711  positive regulation of astrocyte differentiation
GO:0030334  regulation of cell migration
GO:0051966  regulation of synaptic transmission, glutamatergic
GO:0048505  regulation of timing of cell differentiation
GO:0032940  secretion by cell
GO:0033363  secretory granule organization

Cellular Component

GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0031232  extrinsic to external side of plasma membrane
GO:0031594  neuromuscular junction
GO:0031091  platelet alpha granule

Molecular Function

GO:0005539  glycosaminoglycan binding
GO:0008201  heparin binding
GO:0005515  protein binding
GO:0005102  receptor binding
GO:0004867  serine-type endopeptidase inhibitor activity