phosphoinositide-3-kinase, catalytic, gamma polypeptide

詳細情報を見る

同義遺伝子名

PtdIns-3-kinase subunit p110, PI3Kgamma, PIK3CG, PI3CG, p120-PI3K, PIK3, PI3-kinase p110 subunit gamma

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:20.20 末梢血:36.40 脾臓:37.80 胸腺:25.80 骨髄:19.70 脂肪:- 骨:25.60 皮膚:-
GeneChip 大脳:2.66 小脳:2.59 脳幹:2.76 脳梁:2.75 松果体:- 末梢神経:2.70 脊柱:2.80 網膜:- 目:- 動脈:2.81 静脈:2.81 リンパ節:4.15 末梢血:- 脾臓:4.37 胸腺:4.17 骨髄:3.79 脂肪:2.81 骨:- 皮膚:2.75
CAGE 大脳:1.12 小脳:- 脳幹:1.72 脳梁:1.89 松果体:0.61 末梢神経:- 脊柱:2.24 網膜:- 目:- 動脈:1.75 静脈:3.22 リンパ節:3.42 末梢血:- 脾臓:3.46 胸腺:4.12 骨髄:- 脂肪:2.39 骨:- 皮膚:-
RNA-seq 大脳:0.36 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.12 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.78 骨:- 皮膚:-
EST 子宮:9.10 胎盤:3.60 前立腺:- 卵巣:37.30 精巣:34.60 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:4.90    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:2.76 胎盤:2.73 前立腺:2.70 卵巣:2.74 精巣:2.96 心臓:2.65 骨格筋:2.66 食道:2.70 胃:3.01 腸:2.80 結腸:2.94 肝臓:2.76 肺:2.92 膀胱:- 腎臓:2.64 下垂体:2.69 甲状腺:2.77 副腎:2.63 膵臓:2.76 乳腺:2.79 唾液腺:2.58
CAGE 子宮:1.53 胎盤:1.43 前立腺:1.80 卵巣:1.39 精巣:1.19 心臓:1.26 骨格筋:0.77 食道:1.66 胃:- 腸:2.34 結腸:1.92     肝臓:1.25    肺:2.43 膀胱:1.78 腎臓:1.14 下垂体:0.95 甲状腺:1.09 副腎:- 膵臓:1.42 乳腺:1.80 唾液腺:1.82
RNA-seq 子宮:- 胎盤:- 前立腺:0.41 卵巣:0.69 精巣:1.79 心臓:0.34 骨格筋:0.06 食道:- 胃:- 腸:- 結腸:0.27     肝臓:0.11        肺:1.04    膀胱:- 腎臓:0.41 下垂体:- 甲状腺:0.33 副腎:1.61 膵臓:- 乳腺:0.65 唾液腺:-

IDs

Refseq ID NM_002649
Gene ID 5294
Unigene ID Hs.32942
Probe set ID 206370_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105851
GTEx ID ENSG00000105851

オーソログ対応遺伝子

マウス[12]  NM_001146200, NM_001146201, NM_020272
ラット[12]  NM_001146200, NM_001146201, NM_020272

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7520444
7606002
7624799
7721825
8313897
8636073
8798481
9113989
9247029
9341793
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0001525  angiogenesis
GO:0007596  blood coagulation
GO:0001816  cytokine production
GO:0002407  dendritic cell chemotaxis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0006897  endocytosis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0043303  mast cell degranulation
GO:0043066  negative regulation of apoptosis
GO:0055118  negative regulation of cardiac muscle contraction
GO:0010897  negative regulation of triglyceride catabolic process
GO:0030593  neutrophil chemotaxis
GO:0006661  phosphatidylinositol biosynthetic process
GO:0014065  phosphoinositide 3-kinase cascade
GO:0006644  phospholipid metabolic process
GO:0030168  platelet activation
GO:0070527  platelet aggregation
GO:0002675  positive regulation of acute inflammatory response
GO:0043406  positive regulation of MAP kinase activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0002679  respiratory burst during defense response
GO:0032252  secretory granule localization
GO:0042110  T cell activation
GO:0010818  T cell chemotaxis
GO:0042098  T cell proliferation

Cellular Component

GO:0005944  1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0016303  1-phosphatidylinositol-3-kinase activity
GO:0005524  ATP binding
GO:0046875  ephrin receptor binding
GO:0046934  phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0035005  phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035004  phosphoinositide 3-kinase activity
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity