polycystic kidney disease 2 (autosomal dominant)

同義遺伝子名

Polycystwin, Polycystin-2, PKD4, PKD2, Polycystic kidney disease 2 protein homolog, polycystic kidney disease 2 (autosomal dominant), APKD2, R48321, MGC138468, MGC138466

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:26.10

小脳:-

脳幹:-

脳梁:29.20

松果体:-

末梢神経:92

脊柱:-

網膜:-

目:41.10

動脈:89.90

静脈:66.60

リンパ節:70.80

末梢血:-

脾臓:-

胸腺:12.90

骨髄:19.70

脂肪:-

骨:25.60

皮膚:48

GeneChip

大脳:5.73

小脳:5.72

脳幹:5.78

脳梁:6.57

松果体:-

末梢神経:6.95

脊柱:6.21

網膜:-

目:-

動脈:7.99

静脈:7.35

リンパ節:6

末梢血:-

脾臓:5.72

胸腺:6.05

骨髄:5.40

脂肪:7.32

骨:-

皮膚:6.08

CAGE

大脳:2.52

小脳:-

脳幹:2.84

脳梁:3.17

松果体:2.84

末梢神経:-

脊柱:2.56

網膜:-

目:-

動脈:4.82

静脈:2.83

リンパ節:1.68

末梢血:-

脾臓:1.86

胸腺:2.11

骨髄:-

脂肪:3.23

骨:-

皮膚:-

RNA-seq

大脳:2.48

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.94

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.37

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:136.70

胎盤:14.60

前立腺:56.30

卵巣:74.50

精巣:13

心臓:38.30

骨格筋:20.10

食道:342.80

胃:21.20

腸:-

結腸:33.90

肝臓:42.20

肺:73.30

膀胱:-

腎臓:52

下垂体:-

甲状腺:-

副腎:-

膵臓:142.30

乳腺:74.30

唾液腺:-

GeneChip

子宮:7.99

胎盤:6.57

前立腺:6.73

卵巣:8.04

精巣:5.50

心臓:6.70

骨格筋:4.85

食道:5.85

胃:6.74

腸:6.42

結腸:5.35

肝臓:5.69

肺:7.15

膀胱:-

腎臓:7.51

下垂体:5.80

甲状腺:6.73

副腎:7.02

膵臓:5.79

乳腺:6.74

唾液腺:5.15

CAGE

子宮:3.84

胎盤:2.71

前立腺:3.24

卵巣:3.30

精巣:2.42

心臓:3.03

骨格筋:1.91

食道:3.08

胃:-

腸:2.50

結腸:2.88

肝臓:1.69

肺:2.92

膀胱:3.02

腎臓:3.07

下垂体:2.49

甲状腺:2.45

副腎:-

膵臓:2.48

乳腺:3.12

唾液腺:1.67

RNA-seq

子宮:-

胎盤:-

前立腺:4.16

卵巣:4.38

精巣:3.80

心臓:2.71

骨格筋:1.28

食道:-

胃:-

腸:-

結腸:4.24

肝臓:1.39

肺:3.92

膀胱:-

腎臓:4.47

下垂体:-

甲状腺:3.29

副腎:3.12

膵臓:-

乳腺:3.92

唾液腺:-

IDs

Refseq ID	NM_000297
Gene ID	5311
Unigene ID	Hs.181272
Probe set ID	203688_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000118762
GTEx ID	ENSG00000118762

オーソログ対応遺伝子

マウス[1]	NM_008861
ラット [0]

染色体

4q22.1 [88,928,820 - 88,998,929]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR018249

EF-HAND 2

遺伝子オントロジー (GO ID)

Biological Process

GO:0001658	branching involved in ureteric bud morphogenesis
GO:0070588	calcium ion transmembrane transport
GO:0006816	calcium ion transport
GO:0007050	cell cycle arrest
GO:0071498	cellular response to fluid shear stress
GO:0071464	cellular response to hydrostatic pressure
GO:0071470	cellular response to osmotic stress
GO:0034614	cellular response to reactive oxygen species
GO:0051298	centrosome duplication
GO:0042994	cytoplasmic sequestering of transcription factor
GO:0050982	detection of mechanical stimulus
GO:0003127	detection of nodal flow
GO:0007368	determination of left/right symmetry
GO:0001892	embryonic placenta development
GO:0007507	heart development
GO:0001947	heart looping
GO:0007259	JAK-STAT cascade
GO:0001889	liver development
GO:0008285	negative regulation of cell proliferation
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0021915	neural tube development
GO:0060674	placenta blood vessel development
GO:0071158	positive regulation of cell cycle arrest
GO:0031659	positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0031587	positive regulation of inositol-1,4,5-trisphosphate receptor activity
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0030814	regulation of cAMP metabolic process
GO:0042127	regulation of cell proliferation
GO:0051209	release of sequestered calcium ion into cytosol
GO:0021510	spinal cord development

Cellular Component

GO:0045180	basal cortex
GO:0009925	basal plasma membrane
GO:0005911	cell-cell junction
GO:0005929	cilium
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0031941	filamentous actin
GO:0071458	integral to cytosolic side of endoplasmic reticulum membrane
GO:0005887	integral to plasma membrane
GO:0030027	lamellipodium
GO:0005932	microtubule basal body
GO:0031512	motile primary cilium
GO:0031513	nonmotile primary cilium
GO:0005886	plasma membrane
GO:0002133	polycystin complex

Molecular Function

GO:0042805	actinin binding
GO:0051117	ATPase binding
GO:0005509	calcium ion binding
GO:0048763	calcium-induced calcium release activity
GO:0008092	cytoskeletal protein binding
GO:0043398	HLH domain binding
GO:0042802	identical protein binding
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0005245	voltage-gated calcium channel activity
GO:0022843	voltage-gated cation channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005248	voltage-gated sodium channel activity

polycystic kidney disease 2 (autosomal dominant)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function