polo-like kinase 1 (Drosophila)

同義遺伝子名

polo-like kinase 1 (Drosophila), Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, PLK, PLK1, Serine/threonine-protein kinase 13, STPK13, polo-like kinase (Drosophila)

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:17.80

小脳:12.60

脳幹:-

脳梁:58.30

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:41.10

動脈:89.90

静脈:66.60

リンパ節:60.70

末梢血:72.90

脾臓:18.90

胸腺:193.30

骨髄:19.70

脂肪:-

骨:102.40

皮膚:14.40

GeneChip

大脳:4.58

小脳:4.41

脳幹:4.57

脳梁:4.45

松果体:-

末梢神経:4.29

脊柱:4.43

網膜:-

目:-

動脈:4.63

静脈:4.45

リンパ節:4.80

末梢血:-

脾臓:4.30

胸腺:5.94

骨髄:5.55

脂肪:4.61

骨:-

皮膚:4.96

CAGE

大脳:0.04

小脳:-

脳幹:0.06

脳梁:0.24

松果体:0.14

末梢神経:-

脊柱:0.13

網膜:-

目:-

動脈:0.59

静脈:2.46

リンパ節:2.05

末梢血:-

脾臓:2.31

胸腺:4.43

骨髄:-

脂肪:1.37

骨:-

皮膚:-

RNA-seq

大脳:0.61

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.48

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.40

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:25.50

前立腺:-

卵巣:-

精巣:86.50

心臓:25.50

骨格筋:-

食道:-

胃:-

腸:32.40

結腸:42.40

肝臓:73.90

肺:9.80

膀胱:125.60

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:8.90

乳腺:37.20

唾液腺:-

GeneChip

子宮:4.48

胎盤:4.73

前立腺:4.31

卵巣:4.35

精巣:6.39

心臓:4.47

骨格筋:4.52

食道:4.85

胃:4.72

腸:4.71

結腸:5.22

肝臓:4.37

肺:4.24

膀胱:-

腎臓:4.30

下垂体:4.61

甲状腺:4.32

副腎:4.31

膵臓:4.89

乳腺:4.43

唾液腺:4.40

CAGE

子宮:0.69

胎盤:2.07

前立腺:0.39

卵巣:0.60

精巣:3.70

心臓:0.30

骨格筋:0.17

食道:2.07

胃:-

腸:1.99

結腸:2.67

肝臓:0.14

肺:0.74

膀胱:0.33

腎臓:0.62

下垂体:0.24

甲状腺:0.06

副腎:-

膵臓:0

乳腺:0.90

唾液腺:0.83

RNA-seq

子宮:-

胎盤:-

前立腺:0.36

卵巣:0.47

精巣:3.82

心臓:0.22

骨格筋:0.05

食道:-

胃:-

腸:-

結腸:0.50

肝臓:0.13

肺:0.65

膀胱:-

腎臓:0.37

下垂体:-

甲状腺:0.46

副腎:0.77

膵臓:-

乳腺:0.68

唾液腺:-

IDs

Refseq ID	NM_005030
Gene ID	5347
Unigene ID	Hs.592049
Probe set ID	202240_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000166851
GTEx ID	ENSG00000166851

オーソログ対応遺伝子

マウス[1]	NM_011121
ラット [0]

染色体

16p12.2 [23,690,143 - 23,701,688]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007092	activation of anaphase-promoting complex activity during mitotic cell cycle
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0008283	cell proliferation
GO:0051297	centrosome organization
GO:0000910	cytokinesis
GO:0031572	G2/M transition DNA damage checkpoint
GO:0000086	G2/M transition of mitotic cell cycle
GO:0001578	microtubule bundle formation
GO:0007067	mitosis
GO:0000278	mitotic cell cycle
GO:0007094	mitotic cell cycle spindle assembly checkpoint
GO:0007091	mitotic metaphase/anaphase transition
GO:0007077	mitotic nuclear envelope disassembly
GO:0000070	mitotic sister chromatid segregation
GO:0043066	negative regulation of apoptosis
GO:0045736	negative regulation of cyclin-dependent protein kinase activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0018105	peptidyl-serine phosphorylation
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045862	positive regulation of proteolysis
GO:0051443	positive regulation of ubiquitin-protein ligase activity
GO:0051437	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0006468	protein amino acid phosphorylation
GO:0031648	protein destabilization
GO:0071168	protein localization to chromatin
GO:0016567	protein ubiquitination
GO:0051726	regulation of cell cycle
GO:0007346	regulation of mitotic cell cycle
GO:0030071	regulation of mitotic metaphase/anaphase transition
GO:0043393	regulation of protein binding
GO:0051439	regulation of ubiquitin-protein ligase activity during mitotic cell cycle

Cellular Component

GO:0005813	centrosome
GO:0005829	cytosol
GO:0000776	kinetochore
GO:0030496	midbody
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0000942	outer kinetochore of condensed nuclear chromosome
GO:0005819	spindle
GO:0005876	spindle microtubule
GO:0051233	spindle midzone
GO:0000922	spindle pole

Molecular Function

GO:0010997	anaphase-promoting complex binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0008017	microtubule binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity

polo-like kinase 1 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function