promyelocytic leukemia

同義遺伝子名

RING finger protein 71, PML, Probable transcription factor PML, promyelocytic leukemia, PP8675, RNF71, Tripartite motif-containing protein 19, TRIM19, MYL

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:29.60

小脳:37.80

脳幹:-

脳梁:-

松果体:-

末梢神経:61.30

脊柱:112.30

網膜:-

目:52.90

動脈:30

静脈:133.30

リンパ節:192.10

末梢血:72.90

脾臓:18.90

胸腺:128.80

骨髄:59

脂肪:-

骨:64

皮膚:33.60

GeneChip

大脳:6.12

小脳:6.07

脳幹:6.15

脳梁:6.24

松果体:-

末梢神経:6.64

脊柱:6.38

網膜:-

目:-

動脈:7.04

静脈:6.79

リンパ節:7.08

末梢血:-

脾臓:6.98

胸腺:6.62

骨髄:6.96

脂肪:7.23

骨:-

皮膚:6.95

CAGE

大脳:3.81

小脳:-

脳幹:3.58

脳梁:3.49

松果体:3.91

末梢神経:-

脊柱:4.11

網膜:-

目:-

動脈:4.58

静脈:4.74

リンパ節:4.47

末梢血:-

脾臓:4.38

胸腺:4.34

骨髄:-

脂肪:5.14

骨:-

皮膚:-

RNA-seq

大脳:1.59

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.95

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:4.35

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:54.70

胎盤:47.40

前立腺:123.90

卵巣:37.30

精巣:26

心臓:76.60

骨格筋:-

食道:-

胃:21.20

腸:-

結腸:67.80

肝臓:-

肺:53.80

膀胱:-

腎臓:93.60

下垂体:-

甲状腺:-

副腎:50.80

膵臓:124.50

乳腺:111.50

唾液腺:-

GeneChip

子宮:6.62

胎盤:6.42

前立腺:6.28

卵巣:6.63

精巣:6.28

心臓:6.48

骨格筋:6.16

食道:6.75

胃:6.66

腸:6.63

結腸:6.89

肝臓:6.44

肺:7.09

膀胱:-

腎臓:6.40

下垂体:6.56

甲状腺:6.95

副腎:6.77

膵臓:6.49

乳腺:7.11

唾液腺:7.02

CAGE

子宮:4.65

胎盤:3.95

前立腺:4.29

卵巣:4.28

精巣:3.69

心臓:4.41

骨格筋:4.12

食道:4.10

胃:-

腸:3.94

結腸:4.19

肝臓:3.32

肺:4.89

膀胱:4.25

腎臓:3.66

下垂体:3.99

甲状腺:4.06

副腎:-

膵臓:3.59

乳腺:5.21

唾液腺:4.42

RNA-seq

子宮:-

胎盤:-

前立腺:2.26

卵巣:2.65

精巣:2.49

心臓:1.23

骨格筋:1.05

食道:-

胃:-

腸:-

結腸:2.54

肝臓:0.31

肺:3.92

膀胱:-

腎臓:1.15

下垂体:-

甲状腺:2.30

副腎:3.52

膵臓:-

乳腺:3.16

唾液腺:-

IDs

Refseq ID	NM_033250
Gene ID	5371
Unigene ID	Hs.526464
Probe set ID	211012_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140464
GTEx ID	ENSG00000140464

オーソログ対応遺伝子

マウス[4]	NM_008884, NM_178087
ラット[4]	NM_008884, NM_178087

染色体

15q24.1 [74,287,014 - 74,339,112]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000315

Zinc finger, B-box

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0060444	branching involved in mammary gland duct morphogenesis
GO:0007050	cell cycle arrest
GO:0045165	cell fate commitment
GO:0071353	cellular response to interleukin-4
GO:0007182	common-partner SMAD protein phosphorylation
GO:0019221	cytokine-mediated signaling pathway
GO:0051607	defense response to virus
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0032469	endoplasmic reticulum calcium ion homeostasis
GO:0006917	induction of apoptosis
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0051457	maintenance of protein location in nucleus
GO:0030099	myeloid cell differentiation
GO:0016525	negative regulation of angiogenesis
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0045930	negative regulation of mitotic cell cycle
GO:0051974	negative regulation of telomerase activity
GO:0032211	negative regulation of telomere maintenance via telomerase
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0032938	negative regulation of translation in response to oxidative stress
GO:0030578	PML body organization
GO:0060058	positive regulation of apoptosis involved in mammary gland involution
GO:0002230	positive regulation of defense response to virus by host
GO:0031065	positive regulation of histone deacetylation
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
GO:0006461	protein complex assembly
GO:0050821	protein stabilization
GO:0006605	protein targeting
GO:0010522	regulation of calcium ion transport into cytosol
GO:0045343	regulation of MHC class I biosynthetic process
GO:0001932	regulation of protein amino acid phosphorylation
GO:0006355	regulation of transcription, DNA-dependent
GO:0034097	response to cytokine stimulus
GO:0010332	response to gamma radiation
GO:0001666	response to hypoxia
GO:0009411	response to UV
GO:0048384	retinoic acid receptor signaling pathway
GO:0007184	SMAD protein nuclear translocation
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0019048	virus-host interaction

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0031901	early endosome membrane
GO:0042406	extrinsic to endoplasmic reticulum membrane
GO:0016363	nuclear matrix
GO:0031965	nuclear membrane
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0016605	PML body

Molecular Function

GO:0050897	cobalt ion binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0046332	SMAD binding
GO:0032183	SUMO binding
GO:0003713	transcription coactivator activity
GO:0031625	ubiquitin protein ligase binding
GO:0008270	zinc ion binding

promyelocytic leukemia

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function