ATPase, Cu++ transporting, alpha polypeptide

詳細情報を見る

同義遺伝子名

Menkes disease-associated protein, Copper-transporting ATPase 1, MNK, Copper pump 1, ATP7A, MC1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:7.10

小脳:-

脳幹:-

脳梁:58.30

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:20.20

末梢血:36.40

脾臓:-

胸腺:25.80

骨髄:59

脂肪:-

骨:-

皮膚:33.60

GeneChip

大脳:4.30

小脳:3.82

脳幹:4.62

脳梁:4.87

松果体:-

末梢神経:5.11

脊柱:4.60

網膜:-

目:-

動脈:5.08

静脈:4.96

リンパ節:4.91

末梢血:-

脾臓:4.91

胸腺:5.10

骨髄:4.97

脂肪:4.79

骨:-

皮膚:5.81

CAGE

大脳:1.87

小脳:-

脳幹:2.23

脳梁:2.50

松果体:2.48

末梢神経:-

脊柱:2.48

網膜:-

目:-

動脈:2.61

静脈:2.46

リンパ節:2.95

末梢血:-

脾臓:2.96

胸腺:3.14

骨髄:-

脂肪:2.92

骨:-

皮膚:-

RNA-seq

大脳:0.93

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.38

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.50

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:9.10

胎盤:29.10

前立腺:22.50

卵巣:-

精巣:8.70

心臓:25.50

骨格筋:-

食道:-

胃:21.20

腸:-

結腸:17

肝臓:-

肺:9.80

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:5.20

胎盤:4.64

前立腺:6.19

卵巣:5.70

精巣:4.04

心臓:4.62

骨格筋:4.47

食道:4.56

胃:4.64

腸:4.48

結腸:4.25

肝臓:4.30

肺:4.93

膀胱:-

腎臓:4.90

下垂体:5.80

甲状腺:5.18

副腎:5.18

膵臓:4.67

乳腺:5.97

唾液腺:5.12

CAGE

子宮:2.88

胎盤:2.27

前立腺:2.82

卵巣:2.64

精巣:1.68

心臓:2.30

骨格筋:1.86

食道:2.93

胃:-

腸:2.77

結腸:2.46

肝臓:1.93

肺:3.00

膀胱:3.09

腎臓:2.81

下垂体:3.20

甲状腺:2.37

副腎:-

膵臓:1.87

乳腺:2.53

唾液腺:3.19

RNA-seq

子宮:-

胎盤:-

前立腺:2.17

卵巣:1.92

精巣:1.54

心臓:1.15

骨格筋:1.00

食道:-

胃:-

腸:-

結腸:1.36

肝臓:0.63

肺:1.84

膀胱:-

腎臓:1.95

下垂体:-

甲状腺:1.47

副腎:1.24

膵臓:-

乳腺:1.53

唾液腺:-

IDs

Refseq ID	NM_000052
Gene ID	538
Unigene ID	Hs.496414
Probe set ID	205198_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000165240
GTEx ID	ENSG00000165240

オーソログ対応遺伝子

マウス[2]	NM_001109757, NM_009726
ラット [0]

染色体

Xq21.1 [77,166,194 - 77,305,892]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR006403	ATPase, P type, cation/copper-transporter
IPR000695	ATPase, P-type, H+ transporting proton pump
IPR006416	ATPase, P-type, heavy metal translocating
IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
IPR006122	Copper ion-binding
IPR006121	Heavy metal transport/detoxification protein
IPR001802	Mercury scavenger protein

遺伝子オントロジー (GO ID)

Biological Process

GO:0001568	blood vessel development
GO:0001974	blood vessel remodeling
GO:0051216	cartilage development
GO:0006584	catecholamine metabolic process
GO:0006878	cellular copper ion homeostasis
GO:0021954	central nervous system neuron development
GO:0021702	cerebellar Purkinje cell differentiation
GO:0030199	collagen fibril organization
GO:0060003	copper ion export
GO:0015677	copper ion import
GO:0006825	copper ion transport
GO:0048813	dendrite morphogenesis
GO:0010273	detoxification of copper ion
GO:0042417	dopamine metabolic process
GO:0048251	elastic fiber assembly
GO:0051542	elastin biosynthetic process
GO:0042414	epinephrine metabolic process
GO:0030198	extracellular matrix organization
GO:0031069	hair follicle morphogenesis
GO:0001701	in utero embryonic development
GO:0034220	ion transmembrane transport
GO:0007626	locomotory behavior
GO:0048286	lung alveolus development
GO:0007005	mitochondrion organization
GO:0048553	negative regulation of metalloenzyme activity
GO:0043524	negative regulation of neuron apoptosis
GO:0048812	neuron projection morphogenesis
GO:0042421	norepinephrine biosynthetic process
GO:0042415	norepinephrine metabolic process
GO:0018205	peptidyl-lysine modification
GO:0043473	pigmentation
GO:0043085	positive regulation of catalytic activity
GO:0048554	positive regulation of metalloenzyme activity
GO:0051353	positive regulation of oxidoreductase activity
GO:0021860	pyramidal neuron development
GO:0010468	regulation of gene expression
GO:0002082	regulation of oxidative phosphorylation
GO:0001836	release of cytochrome c from mitochondria
GO:0019430	removal of superoxide radicals
GO:0010041	response to iron(III) ion
GO:0010043	response to zinc ion
GO:0042428	serotonin metabolic process
GO:0043588	skin development
GO:0042093	T-helper cell differentiation
GO:0055085	transmembrane transport
GO:0006568	tryptophan metabolic process
GO:0006570	tyrosine metabolic process

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0031526	brush border membrane
GO:0043025	cell soma
GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0005770	late endosome
GO:0043005	neuron projection
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0030141	secretory granule
GO:0005802	trans-Golgi network
GO:0030140	trans-Golgi network transport vesicle

Molecular Function

GO:0005524	ATP binding
GO:0005507	copper ion binding
GO:0005375	copper ion transmembrane transporter activity
GO:0032767	copper-dependent protein binding
GO:0004008	copper-exporting ATPase activity
GO:0005515	protein binding
GO:0016532	superoxide dismutase copper chaperone activity

ATPase, Cu++ transporting, alpha polypeptide

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function