peroxisome proliferator-activated receptor alpha

詳細情報を見る

同義遺伝子名

Peroxisome proliferator-activated receptor alpha, PPAR, hPPAR, MGC2452, peroxisome proliferator-activated receptor alpha, PPARA, NR1C1, PPAR-alpha, MGC2237

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.34 小脳:4.05 脳幹:4.43 脳梁:4.39 松果体:- 末梢神経:4.17 脊柱:4.36 網膜:- 目:- 動脈:4.19 静脈:4.48 リンパ節:4.16 末梢血:- 脾臓:4.19 胸腺:4.29 骨髄:4.29 脂肪:4.21 骨:- 皮膚:4.48
CAGE 大脳:1.75 小脳:- 脳幹:1.79 脳梁:1.98 松果体:1.55 末梢神経:- 脊柱:2.01 網膜:- 目:- 動脈:2.43 静脈:2.01 リンパ節:1.67 末梢血:- 脾臓:1.58 胸腺:0.94 骨髄:- 脂肪:2.07 骨:- 皮膚:-
RNA-seq 大脳:1.49 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.45 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.10 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.22 胎盤:4.33 前立腺:4.22 卵巣:4.45 精巣:4.14 心臓:4.66 骨格筋:5.25 食道:4.37 胃:4.44 腸:4.89 結腸:4.71 肝臓:5.17 肺:4.14 膀胱:- 腎臓:5.24 下垂体:4.24 甲状腺:4.28 副腎:4.34 膵臓:4.66 乳腺:4.13 唾液腺:4.48
CAGE 子宮:1.82 胎盤:1.20 前立腺:2.06 卵巣:1.79 精巣:1.58 心臓:2.70 骨格筋:2.38 食道:2.05 胃:- 腸:3.32 結腸:2.66     肝臓:3.26    肺:1.82 膀胱:2.17 腎臓:2.93 下垂体:1.43 甲状腺:1.81 副腎:- 膵臓:2.66 乳腺:2.19 唾液腺:2.43
RNA-seq 子宮:- 胎盤:- 前立腺:2.06 卵巣:1.85 精巣:1.52 心臓:3.22 骨格筋:3.04 食道:- 胃:- 腸:- 結腸:1.99     肝臓:3.90        肺:1.31    膀胱:- 腎臓:3.15 下垂体:- 甲状腺:1.88 副腎:1.49 膵臓:- 乳腺:1.57 唾液腺:-

IDs

Refseq ID NM_001001928
Gene ID 5465
Unigene ID -
Probe set ID 206870_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000186951
GTEx ID ENSG00000186951

オーソログ対応遺伝子

マウス[2]  NM_001113418, NM_011144
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7684926
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0035095  behavioral response to nicotine
GO:0044255  cellular lipid metabolic process
GO:0070166  enamel mineralization
GO:0008544  epidermis development
GO:0006631  fatty acid metabolic process
GO:0015908  fatty acid transport
GO:0010467  gene expression
GO:0007507  heart development
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0006629  lipid metabolic process
GO:0042157  lipoprotein metabolic process
GO:0032099  negative regulation of appetite
GO:0045776  negative regulation of blood pressure
GO:0010887  negative regulation of cholesterol storage
GO:0045820  negative regulation of glycolysis
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0032091  negative regulation of protein binding
GO:0010871  negative regulation of receptor biosynthetic process
GO:0010891  negative regulation of sequestering of triglyceride
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0032000  positive regulation of fatty acid beta-oxidation
GO:0046321  positive regulation of fatty acid oxidation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0001666  response to hypoxia
GO:0032868  response to insulin stimulus
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0042060  wound healing

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0008144  drug binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0008289  lipid binding
GO:0051525  NFAT protein binding
GO:0019902  phosphatase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0019904  protein domain specific binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0031624  ubiquitin conjugating enzyme binding
GO:0008270  zinc ion binding