mediator complex subunit 1

詳細情報を見る

同義遺伝子名

TRIP-2, Trap220, TRIP2, PPARGBP, PPAR-binding protein, RB18A, p53 regulatory protein RB18A, ARC205, MED1, MGC71488, PPARBP, CRSP200, TRAP220, CRSP1, DRIP205, Activator-recruited cofactor 205 kDa component, DRIP230, Thyroid receptor-interacting protein 2, PPAR binding protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:11.80 動脈:- 静脈:- リンパ節:10.10 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:9.60
GeneChip 大脳:5.60 小脳:5.53 脳幹:5.48 脳梁:5.77 松果体:- 末梢神経:5.91 脊柱:5.63 網膜:- 目:- 動脈:6.01 静脈:5.81 リンパ節:6.38 末梢血:- 脾臓:6.51 胸腺:6.24 骨髄:5.99 脂肪:5.92 骨:- 皮膚:5.81
CAGE 大脳:2.30 小脳:- 脳幹:2.48 脳梁:2.82 松果体:1.90 末梢神経:- 脊柱:2.28 網膜:- 目:- 動脈:2.48 静脈:2.49 リンパ節:2.75 末梢血:- 脾臓:2.82 胸腺:3.21 骨髄:- 脂肪:2.70 骨:- 皮膚:-
RNA-seq 大脳:2.24 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.86 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.91 骨:- 皮膚:-
EST 子宮:9.10 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:9.80    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:6.04 胎盤:5.62 前立腺:5.85 卵巣:6.07 精巣:5.92 心臓:5.85 骨格筋:5.65 食道:5.95 胃:6.25 腸:5.55 結腸:5.86 肝臓:6.03 肺:6.21 膀胱:- 腎臓:5.88 下垂体:5.84 甲状腺:5.99 副腎:6.11 膵臓:5.22 乳腺:6.24 唾液腺:5.58
CAGE 子宮:2.52 胎盤:2.61 前立腺:2.47 卵巣:2.95 精巣:2.74 心臓:2.35 骨格筋:1.99 食道:2.34 胃:- 腸:2.45 結腸:2.56     肝臓:2.31    肺:2.41 膀胱:2.49 腎臓:2.41 下垂体:2.60 甲状腺:2.33 副腎:- 膵臓:2.71 乳腺:2.47 唾液腺:2.01
RNA-seq 子宮:- 胎盤:- 前立腺:2.99 卵巣:3.49 精巣:2.81 心臓:2.46 骨格筋:2.37 食道:- 胃:- 腸:- 結腸:2.64     肝臓:1.79        肺:2.18    膀胱:- 腎臓:2.39 下垂体:- 甲状腺:2.87 副腎:3.03 膵臓:- 乳腺:2.56 唾液腺:-

IDs

Refseq ID NM_004774
Gene ID 5469
Unigene ID Hs.643754
Probe set ID 203496_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125686
GTEx ID ENSG00000125686

オーソログ対応遺伝子

マウス[12]  NM_001080118, NM_013634, NM_134027
ラット[1]  NM_001134361, NM_013634, NM_134027

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006702  androgen biosynthetic process
GO:0030521  androgen receptor signaling pathway
GO:0001525  angiogenesis
GO:0007420  brain development
GO:0000902  cell morphogenesis
GO:0044255  cellular lipid metabolic process
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071383  cellular response to steroid hormone stimulus
GO:0006260  DNA replication
GO:0035050  embryonic heart tube development
GO:0035162  embryonic hemopoiesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0001892  embryonic placenta development
GO:0048822  enucleate erythrocyte development
GO:0060750  epithelial cell proliferation involved in mammary gland duct elongation
GO:0070371  ERK1 and ERK2 cascade
GO:0048821  erythrocyte development
GO:0045444  fat cell differentiation
GO:0010467  gene expression
GO:0030216  keratinocyte differentiation
GO:0007595  lactation
GO:0002088  lens development in camera-type eye
GO:0001889  liver development
GO:0060745  mammary gland branching involved in pregnancy
GO:0060744  mammary gland branching involved in thelarche
GO:0030224  monocyte differentiation
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0043066  negative regulation of apoptosis
GO:0010839  negative regulation of keratinocyte proliferation
GO:0045665  negative regulation of neuron differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0031100  organ regeneration
GO:0033148  positive regulation of estrogen receptor signaling pathway
GO:0070318  positive regulation of G0 to G1 transition
GO:0010628  positive regulation of gene expression
GO:0060335  positive regulation of interferon-gamma-mediated signaling pathway
GO:0045618  positive regulation of keratinocyte differentiation
GO:0033601  positive regulation of mammary gland epithelial cell proliferation
GO:0033160  positive regulation of protein import into nucleus, translocation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051726  regulation of cell cycle
GO:0006356  regulation of transcription from RNA polymerase I promoter
GO:0070562  regulation of vitamin D receptor signaling pathway
GO:0003406  retinal pigment epithelium development
GO:0030518  steroid hormone receptor signaling pathway
GO:0006590  thyroid hormone generation
GO:0002154  thyroid hormone mediated signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0016592  mediator complex
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0030331  estrogen receptor binding
GO:0050693  LBD domain binding
GO:0016922  ligand-dependent nuclear receptor binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0042975  peroxisome proliferator activated receptor binding
GO:0005515  protein binding
GO:0004872  receptor activity
GO:0042974  retinoic acid receptor binding
GO:0046966  thyroid hormone receptor binding
GO:0030375  thyroid hormone receptor coactivator activity
GO:0003713  transcription coactivator activity
GO:0003712  transcription cofactor activity
GO:0008134  transcription factor binding
GO:0042809  vitamin D receptor binding