protein kinase, AMP-activated, alpha 1 catalytic subunit

詳細情報を見る

同義遺伝子名

PRKAA1, MGC57364, AMPKa1, AMPK alpha-1 chain, AMPK1, MGC33776

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:55.70

小脳:12.60

脳幹:-

脳梁:-

松果体:296.70

末梢神経:61.30

脊柱:112.30

網膜:593.20

目:182.20

動脈:60

静脈:866.40

リンパ節:151.70

末梢血:564.80

脾臓:75.60

胸腺:25.80

骨髄:196.80

脂肪:161.30

骨:191.90

皮膚:542.40

GeneChip

大脳:3.62

小脳:3.53

脳幹:3.96

脳梁:3.71

松果体:-

末梢神経:3.80

脊柱:3.80

網膜:-

目:-

動脈:3.82

静脈:4.37

リンパ節:3.96

末梢血:-

脾臓:4.29

胸腺:4.62

骨髄:5.82

脂肪:4.39

骨:-

皮膚:4.49

CAGE

大脳:3.16

小脳:-

脳幹:3.90

脳梁:3.82

松果体:3.17

末梢神経:-

脊柱:3.37

網膜:-

目:-

動脈:3.71

静脈:3.72

リンパ節:3.81

末梢血:-

脾臓:4.02

胸腺:3.69

骨髄:-

脂肪:4.52

骨:-

皮膚:-

RNA-seq

大脳:3.27

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.89

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:4.28

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:164

胎盤:167.60

前立腺:202.80

卵巣:149.10

精巣:190.40

心臓:89.40

骨格筋:40.20

食道:-

胃:424.80

腸:162

結腸:144.20

肝臓:84.40

肺:268.80

膀胱:125.60

腎臓:62.40

下垂体:116

甲状腺:491.20

副腎:101.60

膵臓:391.20

乳腺:390.30

唾液腺:-

GeneChip

子宮:4.04

胎盤:4.58

前立腺:4.51

卵巣:4.01

精巣:7.31

心臓:4.22

骨格筋:3.71

食道:3.98

胃:4.32

腸:4.51

結腸:3.99

肝臓:4.32

肺:3.98

膀胱:-

腎臓:3.80

下垂体:3.40

甲状腺:3.94

副腎:3.47

膵臓:4.32

乳腺:3.67

唾液腺:4.07

CAGE

子宮:4.21

胎盤:3.59

前立腺:4.17

卵巣:4.17

精巣:3.98

心臓:3.56

骨格筋:3.59

食道:3.96

胃:-

腸:4.27

結腸:3.63

肝臓:4.38

肺:3.95

膀胱:4.31

腎臓:4.32

下垂体:3.42

甲状腺:4.05

副腎:-

膵臓:3.50

乳腺:3.47

唾液腺:3.85

RNA-seq

子宮:-

胎盤:-

前立腺:4.39

卵巣:3.97

精巣:3.88

心臓:3.21

骨格筋:2.72

食道:-

胃:-

腸:-

結腸:4.11

肝臓:4.30

肺:4.55

膀胱:-

腎臓:4.33

下垂体:-

甲状腺:4.35

副腎:4.25

膵臓:-

乳腺:3.89

唾液腺:-

IDs

Refseq ID	NM_006251
Gene ID	5562
Unigene ID	Hs.433222
Probe set ID	209799_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000132356
GTEx ID	ENSG00000132356

オーソログ対応遺伝子

マウス[1]	NM_001013367
ラット [0]

染色体

5p13.1 [40,759,481 - 40,798,476]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0006914	autophagy
GO:0007050	cell cycle arrest
GO:0071361	cellular response to ethanol
GO:0042149	cellular response to glucose starvation
GO:0070301	cellular response to hydrogen peroxide
GO:0071456	cellular response to hypoxia
GO:0031669	cellular response to nutrient levels
GO:0006695	cholesterol biosynthetic process
GO:0009631	cold acclimation
GO:0006633	fatty acid biosynthetic process
GO:0055089	fatty acid homeostasis
GO:0019395	fatty acid oxidation
GO:0042593	glucose homeostasis
GO:0006006	glucose metabolic process
GO:0008286	insulin receptor signaling pathway
GO:0008610	lipid biosynthetic process
GO:0043066	negative regulation of apoptosis
GO:0046318	negative regulation of glucosylceramide biosynthetic process
GO:0050995	negative regulation of lipid catabolic process
GO:0032007	negative regulation of TOR signaling pathway
GO:0010508	positive regulation of autophagy
GO:0008284	positive regulation of cell proliferation
GO:0045542	positive regulation of cholesterol biosynthetic process
GO:0010628	positive regulation of gene expression
GO:0045821	positive regulation of glycolysis
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0042752	regulation of circadian rhythm
GO:0006355	regulation of transcription, DNA-dependent
GO:0060627	regulation of vesicle-mediated transport
GO:0014823	response to activity
GO:0031000	response to caffeine
GO:0001666	response to hypoxia
GO:0006950	response to stress
GO:0048511	rhythmic process
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0031588	AMP-activated protein kinase complex
GO:0016324	apical plasma membrane
GO:0005829	cytosol
GO:0005622	intracellular
GO:0005634	nucleus

Molecular Function

GO:0004679	AMP-activated protein kinase activity
GO:0005524	ATP binding
GO:0004691	cAMP-dependent protein kinase activity
GO:0003682	chromatin binding
GO:0035174	histone serine kinase activity
GO:0019900	kinase binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0004672	protein kinase activity
GO:0050321	tau-protein kinase activity
GO:0050405	[acetyl-CoA carboxylase] kinase activity
GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity

protein kinase, AMP-activated, alpha 1 catalytic subunit

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function