protein kinase, AMP-activated, alpha 1 catalytic subunit

詳細情報を見る

同義遺伝子名

PRKAA1, MGC57364, AMPKa1, AMPK alpha-1 chain, AMPK1, MGC33776

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:55.70 小脳:12.60 脳幹:- 脳梁:- 松果体:296.70 末梢神経:61.30 脊柱:112.30 網膜:593.20 目:182.20 動脈:60 静脈:866.40 リンパ節:151.70 末梢血:564.80 脾臓:75.60 胸腺:25.80 骨髄:196.80 脂肪:161.30 骨:191.90 皮膚:542.40
GeneChip 大脳:3.62 小脳:3.53 脳幹:3.96 脳梁:3.71 松果体:- 末梢神経:3.80 脊柱:3.80 網膜:- 目:- 動脈:3.82 静脈:4.37 リンパ節:3.96 末梢血:- 脾臓:4.29 胸腺:4.62 骨髄:5.82 脂肪:4.39 骨:- 皮膚:4.49
CAGE 大脳:3.16 小脳:- 脳幹:3.90 脳梁:3.82 松果体:3.17 末梢神経:- 脊柱:3.37 網膜:- 目:- 動脈:3.71 静脈:3.72 リンパ節:3.81 末梢血:- 脾臓:4.02 胸腺:3.69 骨髄:- 脂肪:4.52 骨:- 皮膚:-
RNA-seq 大脳:3.27 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.89 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.28 骨:- 皮膚:-
EST 子宮:164 胎盤:167.60 前立腺:202.80 卵巣:149.10 精巣:190.40 心臓:89.40 骨格筋:40.20 食道:- 胃:424.80 腸:162 結腸:144.20     肝臓:84.40        肺:268.80    膀胱:125.60 腎臓:62.40 下垂体:116 甲状腺:491.20 副腎:101.60 膵臓:391.20 乳腺:390.30 唾液腺:-
GeneChip 子宮:4.04 胎盤:4.58 前立腺:4.51 卵巣:4.01 精巣:7.31 心臓:4.22 骨格筋:3.71 食道:3.98 胃:4.32 腸:4.51 結腸:3.99 肝臓:4.32 肺:3.98 膀胱:- 腎臓:3.80 下垂体:3.40 甲状腺:3.94 副腎:3.47 膵臓:4.32 乳腺:3.67 唾液腺:4.07
CAGE 子宮:4.21 胎盤:3.59 前立腺:4.17 卵巣:4.17 精巣:3.98 心臓:3.56 骨格筋:3.59 食道:3.96 胃:- 腸:4.27 結腸:3.63     肝臓:4.38    肺:3.95 膀胱:4.31 腎臓:4.32 下垂体:3.42 甲状腺:4.05 副腎:- 膵臓:3.50 乳腺:3.47 唾液腺:3.85
RNA-seq 子宮:- 胎盤:- 前立腺:4.39 卵巣:3.97 精巣:3.88 心臓:3.21 骨格筋:2.72 食道:- 胃:- 腸:- 結腸:4.11     肝臓:4.30        肺:4.55    膀胱:- 腎臓:4.33 下垂体:- 甲状腺:4.35 副腎:4.25 膵臓:- 乳腺:3.89 唾液腺:-

IDs

Refseq ID NM_006251
Gene ID 5562
Unigene ID Hs.433222
Probe set ID 209799_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000132356
GTEx ID ENSG00000132356

オーソログ対応遺伝子

マウス[1]  NM_001013367
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1322130
2900138
7907095
8094892
8163463
8557660
8626596
8663446
8910387
9091312
9224708
9710607
9845345
9857077
10698692
10760274
10862786
11042152
11052978
11165240
11171059
11500364
11546797
11903059
11913976
11971957
11997383
12091379
12194824
12368907
12391032
12477932
12788940
12791703
12847291
12853467
12869384
12890675
14557259
14651849
14702039
14709557
14970221
14976552
14985344
14985505
15024086
15261145
15485651
15489334
16054041
16054095
16306228
16344560
16405649
16466905
16806233
17028174
17088252
17584647
18195011
18276112
18303014
18347656
18359290
18403135
18439900
18614941
18663353
18674809
18781797
18801964
18836454
18950855
18976975
18996102
19020741
19049348
19050283
19138981
19197243
19211918
19322201
19442239
19491292
19502591
19556893
19616115
19720090
19723093
19723094
19723101
19723105
19728147
19887561
19913121
19923924
19948975
19966861
20080969
20103647
20167678
20170185
20217115
20368287
20368732
20392842
20421294
20462511
20538596
20562859
20564492
20602615
20622004
20628086
20660302
20682687
20821366
20861072
20876741
21048031
21072212
21079763
21088205
21139048
21209024
21232561
21344388
21416543
21432774
21474997
21651489
21670147
21678424
21728993
21768291
21775054
21807092
21892142
21906983
21909354
21963094
21987572
21988832
21994947
22007913
22021095
22037551
22065577
22212710
22363791
22378745
22406815
22419736
22434430
22462548
22480519
22553202
22564965
22607554
22674476
22688514
22815988
22833096
22869372
22897928
22935535
22939624
22939629
22988252
23000302
23022380
23171948
23221389
23228943
23291726
23306156
23324179
23367447
23376776
23417417
23418352
23455922
23463002
23475945
23506848
23589839
23592276
23602568
23625915
23648710
23671028
23677989
23712032
23716691
23723070
23728343
23778007
23800577
23819460
23861218
23878245
23883584
23899558
23904275
23963659
23982477
24018441
24047437
24072697
24080159
24095280
24190973
24371122
24441100
24491542
24654937
24797263
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0006914  autophagy
GO:0007050  cell cycle arrest
GO:0071361  cellular response to ethanol
GO:0042149  cellular response to glucose starvation
GO:0070301  cellular response to hydrogen peroxide
GO:0071456  cellular response to hypoxia
GO:0031669  cellular response to nutrient levels
GO:0006695  cholesterol biosynthetic process
GO:0009631  cold acclimation
GO:0006633  fatty acid biosynthetic process
GO:0055089  fatty acid homeostasis
GO:0019395  fatty acid oxidation
GO:0042593  glucose homeostasis
GO:0006006  glucose metabolic process
GO:0008286  insulin receptor signaling pathway
GO:0008610  lipid biosynthetic process
GO:0043066  negative regulation of apoptosis
GO:0046318  negative regulation of glucosylceramide biosynthetic process
GO:0050995  negative regulation of lipid catabolic process
GO:0032007  negative regulation of TOR signaling pathway
GO:0010508  positive regulation of autophagy
GO:0008284  positive regulation of cell proliferation
GO:0045542  positive regulation of cholesterol biosynthetic process
GO:0010628  positive regulation of gene expression
GO:0045821  positive regulation of glycolysis
GO:0006468  protein amino acid phosphorylation
GO:0051291  protein heterooligomerization
GO:0042752  regulation of circadian rhythm
GO:0006355  regulation of transcription, DNA-dependent
GO:0060627  regulation of vesicle-mediated transport
GO:0014823  response to activity
GO:0031000  response to caffeine
GO:0001666  response to hypoxia
GO:0006950  response to stress
GO:0048511  rhythmic process
GO:0007165  signal transduction
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0031588  AMP-activated protein kinase complex
GO:0016324  apical plasma membrane
GO:0005829  cytosol
GO:0005622  intracellular
GO:0005634  nucleus

Molecular Function

GO:0004679  AMP-activated protein kinase activity
GO:0005524  ATP binding
GO:0004691  cAMP-dependent protein kinase activity
GO:0003682  chromatin binding
GO:0035174  histone serine kinase activity
GO:0019900  kinase binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0004672  protein kinase activity
GO:0050321  tau-protein kinase activity
GO:0050405  [acetyl-CoA carboxylase] kinase activity
GO:0047322  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity