protein kinase, DNA-activated, catalytic polypeptide

詳細情報を見る

同義遺伝子名

XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, p350, DNA-dependent protein kinase catalytic subunit, DNPK1, PRKDC, HYRC, HYRC1, DNAPK

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:61.60 小脳:12.60 脳幹:- 脳梁:116.60 松果体:- 末梢神経:61.30 脊柱:336.90 網膜:- 目:88.20 動脈:60 静脈:133.30 リンパ節:70.80 末梢血:54.70 脾臓:56.70 胸腺:90.20 骨髄:98.40 脂肪:40.30 骨:76.80 皮膚:163.20
GeneChip 大脳:6.07 小脳:6.20 脳幹:6.26 脳梁:6.11 松果体:- 末梢神経:6.19 脊柱:6.17 網膜:- 目:- 動脈:5.71 静脈:5.79 リンパ節:6.13 末梢血:- 脾臓:6.12 胸腺:7.73 骨髄:6.50 脂肪:6.29 骨:- 皮膚:6.43
CAGE 大脳:4.25 小脳:- 脳幹:4.02 脳梁:4.09 松果体:4.85 末梢神経:- 脊柱:4.46 網膜:- 目:- 動脈:4.25 静脈:4.21 リンパ節:4.58 末梢血:- 脾臓:4.32 胸腺:4.80 骨髄:- 脂肪:4.05 骨:- 皮膚:-
RNA-seq 大脳:2.66 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.57 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.32 骨:- 皮膚:-
EST 子宮:82 胎盤:54.60 前立腺:202.80 卵巣:186.30 精巣:43.30 心臓:127.70 骨格筋:60.30 食道:- 胃:297.40 腸:- 結腸:288.30     肝臓:200.60        肺:88    膀胱:- 腎臓:62.40 下垂体:- 甲状腺:- 副腎:101.60 膵臓:17.80 乳腺:204.40 唾液腺:-
GeneChip 子宮:6.89 胎盤:6.53 前立腺:6.86 卵巣:6.87 精巣:6.51 心臓:6.10 骨格筋:5.97 食道:6.55 胃:6.08 腸:6.29 結腸:6.27 肝臓:5.30 肺:5.49 膀胱:- 腎臓:5.76 下垂体:6.37 甲状腺:6.11 副腎:5.66 膵臓:6.16 乳腺:6.41 唾液腺:5.60
CAGE 子宮:4.34 胎盤:4.14 前立腺:4.01 卵巣:4.27 精巣:4.13 心臓:4.33 骨格筋:4.12 食道:4.14 胃:- 腸:3.86 結腸:4.30     肝臓:3.91    肺:4.10 膀胱:4.02 腎臓:3.85 下垂体:4.53 甲状腺:3.89 副腎:- 膵臓:4.30 乳腺:4.66 唾液腺:4.20
RNA-seq 子宮:- 胎盤:- 前立腺:2.59 卵巣:3.39 精巣:3.23 心臓:2.34 骨格筋:3.91 食道:- 胃:- 腸:- 結腸:2.46     肝臓:2.09        肺:2.49    膀胱:- 腎臓:2.78 下垂体:- 甲状腺:3.51 副腎:3.21 膵臓:- 乳腺:2.83 唾液腺:-

IDs

Refseq ID NM_006904
Gene ID 5591
Unigene ID Hs.491682
Probe set ID 210543_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000253729
GTEx ID ENSG00000253729

オーソログ対応遺伝子

マウス[1]  NM_011159
ラット[1]  NM_011159

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1597196
2247066
2507541
7594449
7638222
7671312
8364539
8407951
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0002326  B cell lineage commitment
GO:0007420  brain development
GO:0032869  cellular response to insulin stimulus
GO:0006281  DNA repair
GO:0006302  double-strand break repair
GO:0006303  double-strand break repair via nonhomologous end joining
GO:0035234  germ cell programmed cell death
GO:0007507  heart development
GO:0033152  immunoglobulin V(D)J recombination
GO:0045087  innate immune response
GO:0018105  peptidyl-serine phosphorylation
GO:0043065  positive regulation of apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032481  positive regulation of type I interferon production
GO:0002328  pro-B cell differentiation
GO:0031648  protein destabilization
GO:0006464  protein modification process
GO:0010332  response to gamma radiation
GO:0001756  somitogenesis
GO:0033077  T cell differentiation in the thymus
GO:0002360  T cell lineage commitment
GO:0033153  T cell receptor V(D)J recombination
GO:0000723  telomere maintenance

Cellular Component

GO:0005829  cytosol
GO:0005958  DNA-dependent protein kinase-DNA ligase 4 complex
GO:0070419  nonhomologous end joining complex
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005667  transcription factor complex

Molecular Function

GO:0005524  ATP binding
GO:0003677  DNA binding
GO:0004677  DNA-dependent protein kinase activity
GO:0019899  enzyme binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0008134  transcription factor binding