PTK2 protein tyrosine kinase 2

詳細情報を見る

同義遺伝子名

PTK2 protein tyrosine kinase 2, pp125FAK, FADK 1, PTK2, FAK1, FADK, Focal adhesion kinase 1, FAK, Protein-tyrosine kinase 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:315.30 小脳:251.90 脳幹:- 脳梁:379.10 松果体:296.70 末梢神経:276 脊柱:112.30 網膜:118.60 目:123.40 動脈:30 静脈:66.60 リンパ節:111.20 末梢血:18.20 脾臓:56.70 胸腺:116 骨髄:78.70 脂肪:121 骨:102.40 皮膚:297.60
GeneChip 大脳:8.48 小脳:7.45 脳幹:8.43 脳梁:9.21 松果体:- 末梢神経:7.45 脊柱:8.41 網膜:- 目:- 動脈:8.01 静脈:8 リンパ節:6.84 末梢血:- 脾臓:6.89 胸腺:5.58 骨髄:5.14 脂肪:7.52 骨:- 皮膚:6.94
CAGE 大脳:4.61 小脳:- 脳幹:4.75 脳梁:5.18 松果体:4.22 末梢神経:- 脊柱:4.59 網膜:- 目:- 動脈:4.49 静脈:3.78 リンパ節:3.16 末梢血:- 脾臓:3.20 胸腺:2.28 骨髄:- 脂肪:4.00 骨:- 皮膚:-
RNA-seq 大脳:3.76 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.38 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.17 骨:- 皮膚:-
EST 子宮:109.40 胎盤:163.90 前立腺:101.40 卵巣:708 精巣:255.30 心臓:191.60 骨格筋:20.10 食道:- 胃:148.70 腸:97.20 結腸:483.30     肝臓:126.70        肺:195.50    膀胱:- 腎臓:104 下垂体:232 甲状腺:163.70 副腎:152.40 膵臓:142.30 乳腺:297.40 唾液腺:-
GeneChip 子宮:7.77 胎盤:7.84 前立腺:7.92 卵巣:7.70 精巣:7.94 心臓:7.35 骨格筋:6.91 食道:6.75 胃:7.37 腸:7.37 結腸:7.09 肝臓:6.69 肺:7.61 膀胱:- 腎臓:7.57 下垂体:6.63 甲状腺:7.75 副腎:7.71 膵臓:6.51 乳腺:7.59 唾液腺:7.57
CAGE 子宮:4.13 胎盤:4.11 前立腺:3.71 卵巣:3.61 精巣:4.03 心臓:3.90 骨格筋:3.47 食道:3.52 胃:- 腸:3.78 結腸:3.92     肝臓:3.21    肺:3.88 膀胱:3.87 腎臓:3.75 下垂体:3.82 甲状腺:3.64 副腎:- 膵臓:3.84 乳腺:4.18 唾液腺:3.89
RNA-seq 子宮:- 胎盤:- 前立腺:4.58 卵巣:4.42 精巣:4.71 心臓:3.62 骨格筋:4.09 食道:- 胃:- 腸:- 結腸:4.50     肝臓:2.62        肺:4.58    膀胱:- 腎臓:3.94 下垂体:- 甲状腺:4.27 副腎:2.61 膵臓:- 乳腺:2.95 唾液腺:-

IDs

Refseq ID NM_153831
Gene ID 5747
Unigene ID Hs.395482
Probe set ID 208820_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169398
GTEx ID ENSG00000169398

オーソログ対応遺伝子

マウス[3]  NM_001130409, NM_007982
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0048870  cell motility
GO:0006921  cell structure disassembly during apoptosis
GO:0030644  cellular chloride ion homeostasis
GO:0021955  central nervous system neuron axonogenesis
GO:0009790  embryonic development
GO:0043542  endothelial cell migration
GO:0048013  ephrin receptor signaling pathway
GO:0030010  establishment of cell polarity
GO:0040023  establishment of nucleus localization
GO:0030198  extracellular matrix organization
GO:0045444  fat cell differentiation
GO:0060396  growth hormone receptor signaling pathway
GO:0003007  heart morphogenesis
GO:0045087  innate immune response
GO:0007229  integrin-mediated signaling pathway
GO:0007254  JNK cascade
GO:0000226  microtubule cytoskeleton organization
GO:0043066  negative regulation of apoptosis
GO:0050771  negative regulation of axonogenesis
GO:0030336  negative regulation of cell migration
GO:0022408  negative regulation of cell-cell adhesion
GO:0046621  negative regulation of organ growth
GO:0051964  negative regulation of synaptogenesis
GO:0001764  neuron migration
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0001890  placenta development
GO:0030168  platelet activation
GO:0045785  positive regulation of cell adhesion
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0060252  positive regulation of glial cell proliferation
GO:0050766  positive regulation of phagocytosis
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0050806  positive regulation of synaptic transmission
GO:0045909  positive regulation of vasodilation
GO:0046777  protein amino acid autophosphorylation
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0042127  regulation of cell proliferation
GO:0008360  regulation of cell shape
GO:0051493  regulation of cytoskeleton organization
GO:0010594  regulation of endothelial cell migration
GO:0051893  regulation of focal adhesion formation
GO:0045667  regulation of osteoblast differentiation
GO:0032319  regulation of Rho GTPase activity
GO:0046685  response to arsenic
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0009749  response to glucose stimulus
GO:0009612  response to mechanical stimulus
GO:0007172  signal complex assembly
GO:0001570  vasculogenesis

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005925  focal adhesion
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0005815  microtubule organizing center
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0042383  sarcolemma

Molecular Function

GO:0003779  actin binding
GO:0005524  ATP binding
GO:0005178  integrin binding
GO:0008432  JUN kinase binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0043548  phosphoinositide 3-kinase binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0042169  SH2 domain binding
GO:0004871  signal transducer activity