protein tyrosine phosphatase, non-receptor type 2

同義遺伝子名

TCELLPTP, TCPTP, protein tyrosine phosphatase, non-receptor type 2, Tyrosine-protein phosphatase non-receptor type 2, TC-PTP, PTPT, PTPN2, T-cell protein-tyrosine phosphatase

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:4.49

小脳:5.50

脳幹:4.46

脳梁:4.96

松果体:-

末梢神経:4.88

脊柱:4.55

網膜:-

目:-

動脈:5.40

静脈:5.66

リンパ節:6.65

末梢血:-

脾臓:6.96

胸腺:8.73

骨髄:6.36

脂肪:5.54

骨:-

皮膚:5.87

CAGE

大脳:3.31

小脳:-

脳幹:3.10

脳梁:2.75

松果体:3.97

末梢神経:-

脊柱:4.04

網膜:-

目:-

動脈:3.23

静脈:3.96

リンパ節:3.88

末梢血:-

脾臓:3.84

胸腺:4.64

骨髄:-

脂肪:3.25

骨:-

皮膚:-

RNA-seq

大脳:0.75

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:4.07

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.93

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:6.15

胎盤:6.02

前立腺:5.89

卵巣:6.82

精巣:5.23

心臓:5.38

骨格筋:4.59

食道:5.84

胃:6.01

腸:5.91

結腸:5.53

肝臓:5.73

肺:6.47

膀胱:-

腎臓:5.17

下垂体:5.38

甲状腺:5.71

副腎:5.51

膵臓:6.28

乳腺:6.04

唾液腺:5.90

CAGE

子宮:3.02

胎盤:3.21

前立腺:3.23

卵巣:3.33

精巣:3.00

心臓:3.28

骨格筋:2.91

食道:2.93

胃:-

腸:3.17

結腸:3.11

肝臓:3.49

肺:3.68

膀胱:3.31

腎臓:2.93

下垂体:3.89

甲状腺:3.11

副腎:-

膵臓:3.59

乳腺:3.75

唾液腺:2.95

RNA-seq

子宮:-

胎盤:-

前立腺:3.28

卵巣:3.73

精巣:3.38

心臓:1.87

骨格筋:2.59

食道:-

胃:-

腸:-

結腸:3.29

肝臓:1.74

肺:3.83

膀胱:-

腎臓:2.61

下垂体:-

甲状腺:2.21

副腎:2.79

膵臓:-

乳腺:2.80

唾液腺:-

IDs

Refseq ID	NM_080422
Gene ID	5771
Unigene ID	-
Probe set ID	213137_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000175354
GTEx ID	ENSG00000175354

オーソログ対応遺伝子

マウス[4]	NM_001127177, NM_008977
ラット [0]

染色体

18p11.21 [12,785,477 - 12,884,337]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000242

Protein-tyrosine phosphatase, receptor/non-receptor type

遺伝子オントロジー (GO ID)

Biological Process

GO:0030183	B cell differentiation
GO:0019221	cytokine-mediated signaling pathway
GO:0030218	erythrocyte differentiation
GO:0042593	glucose homeostasis
GO:0008286	insulin receptor signaling pathway
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0008285	negative regulation of cell proliferation
GO:0050922	negative regulation of chemotaxis
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0050728	negative regulation of inflammatory response
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway
GO:0070104	negative regulation of interleukin-6-mediated signaling pathway
GO:0010888	negative regulation of lipid storage
GO:0045650	negative regulation of macrophage differentiation
GO:0050860	negative regulation of T cell receptor signaling pathway
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0060339	negative regulation of type I interferon-mediated signaling pathway
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0042527	negative regulation of tyrosine phosphorylation of Stat6 protein
GO:0045722	positive regulation of gluconeogenesis
GO:0060334	regulation of interferon-gamma-mediated signaling pathway
GO:0030217	T cell differentiation

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005793	ER-Golgi intermediate compartment
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005178	integrin binding
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004725	protein tyrosine phosphatase activity
GO:0030971	receptor tyrosine kinase binding
GO:0019905	syntaxin binding

protein tyrosine phosphatase, non-receptor type 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function