BCL2-antagonist/killer 1

詳細情報を見る

同義遺伝子名

Bcl-2 homologous antagonist/killer, BAK 1, BAK, MGC3887, Bcl-2-like 7 protein, BCL2L7, Apoptosis regulator BAK, BAK-LIKE, BAK1, CDN1, BAK-1, MGC117255, BCL2-antagonist/killer 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:4.70 小脳:12.60 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:17.60 動脈:- 静脈:66.60 リンパ節:10.10 末梢血:72.90 脾臓:18.90 胸腺:25.80 骨髄:19.70 脂肪:- 骨:- 皮膚:9.60
GeneChip 大脳:5.40 小脳:5.69 脳幹:5.41 脳梁:5.47 松果体:- 末梢神経:5.60 脊柱:5.42 網膜:- 目:- 動脈:5.78 静脈:5.69 リンパ節:6.31 末梢血:- 脾臓:6.25 胸腺:5.80 骨髄:5.72 脂肪:5.67 骨:- 皮膚:6.03
CAGE 大脳:1.97 小脳:- 脳幹:1.88 脳梁:2.21 松果体:1.92 末梢神経:- 脊柱:1.90 網膜:- 目:- 動脈:2.02 静脈:1.89 リンパ節:2.55 末梢血:- 脾臓:2.82 胸腺:2.50 骨髄:- 脂肪:2.22 骨:- 皮膚:-
RNA-seq 大脳:1.89 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.31 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.11 骨:- 皮膚:-
EST 子宮:9.10 胎盤:43.70 前立腺:- 卵巣:- 精巣:4.30 心臓:12.80 骨格筋:20.10 食道:- 胃:85 腸:64.80 結腸:17     肝臓:10.60        肺:53.80    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.57 胎盤:5.74 前立腺:5.49 卵巣:5.35 精巣:5.51 心臓:5.80 骨格筋:5.90 食道:6.06 胃:5.97 腸:5.94 結腸:6.27 肝臓:5.73 肺:5.92 膀胱:- 腎臓:5.73 下垂体:5.83 甲状腺:5.53 副腎:6.45 膵臓:5.82 乳腺:5.79 唾液腺:6
CAGE 子宮:2.10 胎盤:2.19 前立腺:2.05 卵巣:1.97 精巣:2.03 心臓:2.28 骨格筋:1.75 食道:2.91 胃:- 腸:3.27 結腸:3.02     肝臓:1.97    肺:2.35 膀胱:2.09 腎臓:2.43 下垂体:1.78 甲状腺:1.87 副腎:- 膵臓:2.08 乳腺:1.80 唾液腺:2.12
RNA-seq 子宮:- 胎盤:- 前立腺:2.58 卵巣:2.73 精巣:2.30 心臓:2.04 骨格筋:1.65 食道:- 胃:- 腸:- 結腸:2.51     肝臓:1.69        肺:2.84    膀胱:- 腎臓:3.33 下垂体:- 甲状腺:2.47 副腎:3.19 膵臓:- 乳腺:2.24 唾液腺:-

IDs

Refseq ID NM_001188
Gene ID 578
Unigene ID Hs.485139
Probe set ID 203728_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000030110
GTEx ID ENSG00000030110

オーソログ対応遺伝子

マウス[2]  NM_007523
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7715729
7715730
7715731
8521816
8887627
9020082
9111042
9463381
9573342
9843949
9878060
10085290
10365962
10381623
10381646
10579309
10639121
10837489
10950869
11175750
11206074
11326099
11571294
11728179
11795669
11867266
11908704
11929871
11932420
11940658
11964315
12070120
12137781
12176904
12297281
12454021
12477932
12624108
12624178
12721291
12808108
12847083
12881569
14574404
14596824
14647456
14702039
14980220
15003505
15077116
15124764
15159409
15194786
15248898
15292519
15322047
15351796
15467752
15478112
15489334
15637055
15638360
15638362
15757910
15846303
15846589
15901672
16172118
16189514
16199525
16341674
16376985
16410245
16436379
16439990
16529740
16645094
16712791
16794010
16847458
16874066
16978419
16988840
17015472
17074758
17188240
17227835
17235284
17289999
17353931
17513609
17686864
17698840
17699158
17724463
17879944
17880809
17927446
17991745
18056640
18178565
18251703
18299329
18309324
18349538
18362892
18387192
18413764
18471982
18472157
18524770
18593893
18636124
18665919
18676680
18715924
18927073
19041633
19056676
19060904
19074885
19135534
19148187
19168699
19170196
19255499
19282307
19343496
19351886
19381065
19463775
19481066
19483681
19514060
19587033
19593445
19625176
19692168
19820697
19875445
19898928
19913121
19955184
20034877
20139978
20308427
20428767
20453000
20460378
20503275
20561923
20618440
20628086
20629644
20836993
20855536
20877624
20930068
20959805
20978950
21036904
21041309
21148306
21158936
21159883
21196599
21233848
21613222
21617256
21656147
21658363
21712378
21726118
21727192
21852253
21900206
21988832
22024133
22056880
22065578
22072546
22139419
22188816
22253918
22257632
22297299
22354970
22378505
22423221
22440942
22479585
22493436
22504646
22515821
22526391
22686245
22700719
22719244
22939629
23140172
23189150
23192964
23217248
23229512
23242420
23251661
23263863
23283967
23303126
23389372
23404709
23480852
23604079
23666239
23666240
23770605
23798675
23928699
23954442
23954445
23966164
24026423
24074954
24097825
24100034
24130482
24265320
24292274
24680709

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008635  activation of caspase activity by cytochrome c
GO:0007568  aging
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0002352  B cell negative selection
GO:0001974  blood vessel remodeling
GO:0007420  brain development
GO:0008283  cell proliferation
GO:0071260  cellular response to mechanical stimulus
GO:0034644  cellular response to UV
GO:0031018  endocrine pancreas development
GO:0010248  establishment or maintenance of transmembrane electrochemical gradient
GO:0035108  limb morphogenesis
GO:0008053  mitochondrial fusion
GO:0002262  myeloid cell homeostasis
GO:0008285  negative regulation of cell proliferation
GO:0010629  negative regulation of gene expression
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0031100  organ regeneration
GO:0043065  positive regulation of apoptosis
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0045862  positive regulation of proteolysis
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0048597  post-embryonic camera-type eye morphogenesis
GO:0032471  reduction of endoplasmic reticulum calcium ion concentration
GO:0051726  regulation of cell cycle
GO:0046902  regulation of mitochondrial membrane permeability
GO:0051881  regulation of mitochondrial membrane potential
GO:0043497  regulation of protein heterodimerization activity
GO:0043496  regulation of protein homodimerization activity
GO:0001836  release of cytochrome c from mitochondria
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0009620  response to fungus
GO:0010332  response to gamma radiation
GO:0042542  response to hydrogen peroxide
GO:0010046  response to mycotoxin
GO:0014070  response to organic cyclic substance
GO:0010225  response to UV-C
GO:0060068  vagina development

Cellular Component

GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0031307  integral to mitochondrial outer membrane
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion
GO:0046930  pore complex

Molecular Function

GO:0051400  BH domain binding
GO:0051087  chaperone binding
GO:0031072  heat shock protein binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity