protein tyrosine phosphatase, non-receptor type 11

詳細情報を見る

同義遺伝子名

PTP-2C, SH-PTP2, SHP2, Protein-tyrosine phosphatase 2C, SH-PTP3, SHP-2, PTPN11, MGC14433, Shp2, BPTP3, PTP2C, SHPTP2, CFC, PTP-1D, Tyrosine-protein phosphatase non-receptor type 11, NS1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:80.60 小脳:37.80 脳幹:- 脳梁:58.30 松果体:296.70 末梢神経:122.70 脊柱:- 網膜:- 目:17.60 動脈:60 静脈:- リンパ節:91 末梢血:36.40 脾臓:56.70 胸腺:51.50 骨髄:39.40 脂肪:40.30 骨:64 皮膚:182.40
GeneChip 大脳:3.25 小脳:3.34 脳幹:3.25 脳梁:3.35 松果体:- 末梢神経:2.90 脊柱:3.20 網膜:- 目:- 動脈:2.89 静脈:3.01 リンパ節:2.86 末梢血:- 脾臓:2.95 胸腺:3.26 骨髄:3.09 脂肪:3.08 骨:- 皮膚:2.91
CAGE 大脳:3.61 小脳:- 脳幹:3.78 脳梁:3.50 松果体:3.24 末梢神経:- 脊柱:3.89 網膜:- 目:- 動脈:3.52 静脈:2.37 リンパ節:2.49 末梢血:- 脾臓:2.24 胸腺:2.40 骨髄:- 脂肪:2.88 骨:- 皮膚:-
RNA-seq 大脳:5.76 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.14 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.08 骨:- 皮膚:-
EST 子宮:82 胎盤:47.40 前立腺:33.80 卵巣:596.20 精巣:30.30 心臓:89.40 骨格筋:- 食道:- 胃:191.20 腸:- 結腸:50.90     肝臓:42.20        肺:34.20    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:163.70 副腎:- 膵臓:62.20 乳腺:83.60 唾液腺:-
GeneChip 子宮:3.06 胎盤:3.04 前立腺:2.97 卵巣:3.10 精巣:2.88 心臓:3.09 骨格筋:3.25 食道:2.99 胃:3.03 腸:3.22 結腸:3.10 肝臓:2.97 肺:3.05 膀胱:- 腎臓:2.99 下垂体:3 甲状腺:2.84 副腎:2.92 膵臓:3.13 乳腺:2.97 唾液腺:3.12
CAGE 子宮:2.75 胎盤:2.40 前立腺:2.74 卵巣:2.50 精巣:2.01 心臓:3.12 骨格筋:3.73 食道:2.73 胃:- 腸:2.34 結腸:2.78     肝臓:3.08    肺:2.90 膀胱:3.03 腎臓:2.54 下垂体:2.87 甲状腺:2.57 副腎:- 膵臓:2.08 乳腺:3.71 唾液腺:1.95
RNA-seq 子宮:- 胎盤:- 前立腺:4.58 卵巣:4.36 精巣:4.54 心臓:4.92 骨格筋:5.22 食道:- 胃:- 腸:- 結腸:5.07     肝臓:4.53        肺:4.46    膀胱:- 腎臓:4.58 下垂体:- 甲状腺:5.00 副腎:4.25 膵臓:- 乳腺:5.84 唾液腺:-

IDs

Refseq ID NM_002834
Gene ID 5781
Unigene ID Hs.506852
Probe set ID 205867_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000179295
GTEx ID ENSG00000179295

オーソログ対応遺伝子

マウス[12]  NM_001109992, NM_011202
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1280823
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0007420  brain development
GO:0019221  cytokine-mediated signaling pathway
GO:0000077  DNA damage checkpoint
GO:0048013  ephrin receptor signaling pathway
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0060325  face morphogenesis
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0048806  genitalia development
GO:0042593  glucose homeostasis
GO:0007507  heart development
GO:0042445  hormone metabolic process
GO:0009755  hormone-mediated signaling pathway
GO:0045087  innate immune response
GO:0048839  inner ear development
GO:0008286  insulin receptor signaling pathway
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0050900  leukocyte migration
GO:0051463  negative regulation of cortisol secretion
GO:0060125  negative regulation of growth hormone secretion
GO:0046676  negative regulation of insulin secretion
GO:0048011  nerve growth factor receptor signaling pathway
GO:0035265  organ growth
GO:0048015  phosphoinositide-mediated signaling
GO:0046887  positive regulation of hormone secretion
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0060334  regulation of interferon-gamma-mediated signaling pathway
GO:0040014  regulation of multicellular organism growth
GO:0046825  regulation of protein export from nucleus
GO:0060338  regulation of type I interferon-mediated signaling pathway
GO:0048609  reproductive process in a multicellular organism
GO:0031295  T cell costimulation
GO:0006641  triglyceride metabolic process
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0005158  insulin receptor binding
GO:0043560  insulin receptor substrate binding
GO:0004726  non-membrane spanning protein tyrosine phosphatase activity
GO:0051428  peptide hormone receptor binding
GO:0043274  phospholipase binding
GO:0004721  phosphoprotein phosphatase activity
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0004725  protein tyrosine phosphatase activity
GO:0030971  receptor tyrosine kinase binding
GO:0005070  SH3/SH2 adaptor activity