BCL2-associated X protein

詳細情報を見る

同義遺伝子名

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発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:11.80 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.80 皮膚:-
GeneChip 大脳:4.76 小脳:4.96 脳幹:4.75 脳梁:4.72 松果体:- 末梢神経:4.37 脊柱:4.55 網膜:- 目:- 動脈:4.44 静脈:4.92 リンパ節:4.82 末梢血:- 脾臓:4.94 胸腺:5.47 骨髄:4.92 脂肪:4.48 骨:- 皮膚:4.25
CAGE 大脳:2.51 小脳:- 脳幹:2.68 脳梁:2.81 松果体:1.94 末梢神経:- 脊柱:2.65 網膜:- 目:- 動脈:3.24 静脈:3.37 リンパ節:3.27 末梢血:- 脾臓:3.66 胸腺:3.51 骨髄:- 脂肪:2.72 骨:- 皮膚:-
RNA-seq 大脳:1.99 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.48 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.57 骨:- 皮膚:-
EST 子宮:- 胎盤:3.60 前立腺:- 卵巣:37.30 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.65 胎盤:4.63 前立腺:4.24 卵巣:5.11 精巣:3.90 心臓:4.95 骨格筋:4.53 食道:4.79 胃:4.70 腸:5.07 結腸:5.42 肝臓:4.47 肺:5.13 膀胱:- 腎臓:4.76 下垂体:4.63 甲状腺:4.65 副腎:4.29 膵臓:4.90 乳腺:4.34 唾液腺:4.65
CAGE 子宮:2.63 胎盤:3.06 前立腺:2.92 卵巣:2.89 精巣:2.53 心臓:2.84 骨格筋:2.13 食道:2.88 胃:- 腸:3.39 結腸:3.47     肝臓:3.18    肺:3.49 膀胱:2.80 腎臓:2.99 下垂体:2.39 甲状腺:2.89 副腎:- 膵臓:2.76 乳腺:3.16 唾液腺:2.26
RNA-seq 子宮:- 胎盤:- 前立腺:2.06 卵巣:2.48 精巣:1.83 心臓:1.65 骨格筋:1.80 食道:- 胃:- 腸:- 結腸:1.06     肝臓:1.44        肺:3.28    膀胱:- 腎臓:1.42 下垂体:- 甲状腺:2.62 副腎:3.49 膵臓:- 乳腺:1.56 唾液腺:-

IDs

Refseq ID NM_004324
Gene ID 581
Unigene ID Hs.624291
Probe set ID 208478_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000087088
GTEx ID ENSG00000087088

オーソログ対応遺伝子

マウス[1]  NM_007527
ラット[1]  NM_007527

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7566098
7607685
7834749
8358790
8521816
8580080
8760290
8889548
8961277
9020077
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24113173
24127964
24139400
24161344
24200861
24379070
24434006
24583282
24680709

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0008635  activation of caspase activity by cytochrome c
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0008637  apoptotic mitochondrial changes
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0002358  B cell homeostatic proliferation
GO:0002352  B cell negative selection
GO:0001974  blood vessel remodeling
GO:0071310  cellular response to organic substance
GO:0034644  cellular response to UV
GO:0021987  cerebral cortex development
GO:0006922  cleavage of lamin
GO:0045136  development of secondary sexual characteristics
GO:0006309  DNA fragmentation involved in apoptosis
GO:0010248  establishment or maintenance of transmembrane electrochemical gradient
GO:0009566  fertilization
GO:0007281  germ cell development
GO:0035234  germ cell programmed cell death
GO:0006687  glycosphingolipid metabolic process
GO:0048873  homeostasis of number of cells within a tissue
GO:0021854  hypothalamus development
GO:0006917  induction of apoptosis
GO:0001822  kidney development
GO:0035108  limb morphogenesis
GO:0043653  mitochondrial fragmentation during apoptosis
GO:0008053  mitochondrial fusion
GO:0002262  myeloid cell homeostasis
GO:0048147  negative regulation of fibroblast proliferation
GO:0043524  negative regulation of neuron apoptosis
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0032091  negative regulation of protein binding
GO:0051402  neuron apoptosis
GO:0001764  neuron migration
GO:0030264  nuclear fragmentation during apoptosis
GO:0042475  odontogenesis of dentine-containing tooth
GO:0001541  ovarian follicle development
GO:0043065  positive regulation of apoptosis
GO:0060058  positive regulation of apoptosis involved in mammary gland involution
GO:0002904  positive regulation of B cell apoptosis
GO:0043525  positive regulation of neuron apoptosis
GO:0048087  positive regulation of pigmentation during development
GO:0032461  positive regulation of protein oligomerization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0051281  positive regulation of release of sequestered calcium ion into cytosol
GO:0048597  post-embryonic camera-type eye morphogenesis
GO:0051260  protein homooligomerization
GO:0001844  protein insertion into mitochondrial membrane during induction of apoptosis
GO:0051259  protein oligomerization
GO:0032471  reduction of endoplasmic reticulum calcium ion concentration
GO:0051726  regulation of cell cycle
GO:0033599  regulation of mammary gland epithelial cell proliferation
GO:0051881  regulation of mitochondrial membrane potential
GO:0006808  regulation of nitrogen utilization
GO:0043497  regulation of protein heterodimerization activity
GO:0043496  regulation of protein homodimerization activity
GO:0001836  release of cytochrome c from mitochondria
GO:0032976  release of matrix enzymes from mitochondria
GO:0001101  response to acid
GO:0048678  response to axon injury
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0009651  response to salt stress
GO:0009636  response to toxin
GO:0060041  retina development in camera-type eye
GO:0046666  retinal cell programmed cell death
GO:0060011  Sertoli cell proliferation
GO:0048515  spermatid differentiation
GO:0001777  T cell homeostatic proliferation
GO:0006927  transformed cell apoptosis
GO:0060068  vagina development
GO:0019048  virus-host interaction

Cellular Component

GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005741  mitochondrial outer membrane
GO:0005757  mitochondrial permeability transition pore complex
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0046930  pore complex

Molecular Function

GO:0051434  BH3 domain binding
GO:0015267  channel activity
GO:0042802  identical protein binding
GO:0008289  lipid binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity