BCL2-associated X protein

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:11.80 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.80 皮膚:-
GeneChip 大脳:4.88 小脳:4.82 脳幹:4.93 脳梁:4.95 松果体:- 末梢神経:4.83 脊柱:4.80 網膜:- 目:- 動脈:5.24 静脈:5.34 リンパ節:5.55 末梢血:- 脾臓:5.96 胸腺:6.75 骨髄:5.78 脂肪:4.94 骨:- 皮膚:5.02
CAGE 大脳:2.51 小脳:- 脳幹:2.68 脳梁:2.81 松果体:1.94 末梢神経:- 脊柱:2.65 網膜:- 目:- 動脈:3.24 静脈:3.37 リンパ節:3.27 末梢血:- 脾臓:3.66 胸腺:3.51 骨髄:- 脂肪:2.72 骨:- 皮膚:-
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.00 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:3.60 前立腺:- 卵巣:37.30 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.29 胎盤:5.35 前立腺:5.16 卵巣:5.76 精巣:4.80 心臓:5 骨格筋:4.83 食道:5.27 胃:5.15 腸:5.63 結腸:6.01 肝臓:4.84 肺:6 膀胱:- 腎臓:5.35 下垂体:5.10 甲状腺:5.25 副腎:4.95 膵臓:5.30 乳腺:5.06 唾液腺:4.67
CAGE 子宮:2.63 胎盤:3.06 前立腺:2.92 卵巣:2.89 精巣:2.53 心臓:2.84 骨格筋:2.13 食道:2.88 胃:- 腸:3.39 結腸:3.47     肝臓:3.18    肺:3.49 膀胱:2.80 腎臓:2.99 下垂体:2.39 甲状腺:2.89 副腎:- 膵臓:2.76 乳腺:3.16 唾液腺:2.26
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.00 精巣:0.00 心臓:0.00 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.00        肺:0.00    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.00 副腎:0.00 膵臓:- 乳腺:0.00 唾液腺:-

詳細情報

IDs

Refseq ID NM_138764
Gene ID 581
Unigene ID Hs.624291
Probe set ID 211833_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000087088
GTEx ID ENSG00000087088

オーソログ対応遺伝子

マウス[1]  NM_007527
ラット[1]  NM_007527

染色体

19q13.33  [49,458,072  -  49,465,055]

遺伝子ファミリー (Interpro ID)

IPR000712  Apoptosis regulator, Bcl-2, BH
IPR002475  BCL2-like apoptosis inhibitor

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0008635  activation of caspase activity by cytochrome c
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0008637  apoptotic mitochondrial changes
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0002358  B cell homeostatic proliferation
GO:0002352  B cell negative selection
GO:0001974  blood vessel remodeling
GO:0071310  cellular response to organic substance
GO:0034644  cellular response to UV
GO:0021987  cerebral cortex development
GO:0006922  cleavage of lamin
GO:0045136  development of secondary sexual characteristics
GO:0006309  DNA fragmentation involved in apoptosis
GO:0010248  establishment or maintenance of transmembrane electrochemical gradient
GO:0009566  fertilization
GO:0007281  germ cell development
GO:0035234  germ cell programmed cell death
GO:0006687  glycosphingolipid metabolic process
GO:0048873  homeostasis of number of cells within a tissue
GO:0021854  hypothalamus development
GO:0006917  induction of apoptosis
GO:0001822  kidney development
GO:0035108  limb morphogenesis
GO:0043653  mitochondrial fragmentation during apoptosis
GO:0008053  mitochondrial fusion
GO:0002262  myeloid cell homeostasis
GO:0048147  negative regulation of fibroblast proliferation
GO:0043524  negative regulation of neuron apoptosis
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0032091  negative regulation of protein binding
GO:0051402  neuron apoptosis
GO:0001764  neuron migration
GO:0030264  nuclear fragmentation during apoptosis
GO:0042475  odontogenesis of dentine-containing tooth
GO:0001541  ovarian follicle development
GO:0043065  positive regulation of apoptosis
GO:0060058  positive regulation of apoptosis involved in mammary gland involution
GO:0002904  positive regulation of B cell apoptosis
GO:0043525  positive regulation of neuron apoptosis
GO:0048087  positive regulation of pigmentation during development
GO:0032461  positive regulation of protein oligomerization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0051281  positive regulation of release of sequestered calcium ion into cytosol
GO:0048597  post-embryonic camera-type eye morphogenesis
GO:0051260  protein homooligomerization
GO:0001844  protein insertion into mitochondrial membrane during induction of apoptosis
GO:0051259  protein oligomerization
GO:0032471  reduction of endoplasmic reticulum calcium ion concentration
GO:0051726  regulation of cell cycle
GO:0033599  regulation of mammary gland epithelial cell proliferation
GO:0051881  regulation of mitochondrial membrane potential
GO:0006808  regulation of nitrogen utilization
GO:0043497  regulation of protein heterodimerization activity
GO:0043496  regulation of protein homodimerization activity
GO:0001836  release of cytochrome c from mitochondria
GO:0032976  release of matrix enzymes from mitochondria
GO:0001101  response to acid
GO:0048678  response to axon injury
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0009651  response to salt stress
GO:0009636  response to toxin
GO:0060041  retina development in camera-type eye
GO:0046666  retinal cell programmed cell death
GO:0060011  Sertoli cell proliferation
GO:0048515  spermatid differentiation
GO:0001777  T cell homeostatic proliferation
GO:0006927  transformed cell apoptosis
GO:0060068  vagina development
GO:0019048  virus-host interaction

Cellular Component

GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005741  mitochondrial outer membrane
GO:0005757  mitochondrial permeability transition pore complex
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0046930  pore complex

Molecular Function

GO:0051434  BH3 domain binding
GO:0015267  channel activity
GO:0042802  identical protein binding
GO:0008289  lipid binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity