ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

詳細情報を見る

同義遺伝子名

MGC111543, RAC1, TC-25, p21-Rac1, Ras-like protein TC25, MIG5

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:181.30 小脳:88.20 脳幹:- 脳梁:87.50 松果体:- 末梢神経:490.80 脊柱:336.90 網膜:118.60 目:188.10 動脈:119.90 静脈:199.90 リンパ節:131.40 末梢血:36.40 脾臓:75.60 胸腺:116 骨髄:216.50 脂肪:80.70 骨:76.80 皮膚:316.80
GeneChip 大脳:10.19 小脳:9.67 脳幹:10.24 脳梁:10.32 松果体:- 末梢神経:10.13 脊柱:10.29 網膜:- 目:- 動脈:10.12 静脈:9.69 リンパ節:9.74 末梢血:- 脾臓:9.60 胸腺:9.72 骨髄:9.07 脂肪:9.85 骨:- 皮膚:10.42
CAGE 大脳:5.14 小脳:- 脳幹:4.97 脳梁:5.34 松果体:4.18 末梢神経:- 脊柱:5.17 網膜:- 目:- 動脈:4.95 静脈:4.33 リンパ節:4.54 末梢血:- 脾臓:4.44 胸腺:4.54 骨髄:- 脂肪:4.44 骨:- 皮膚:-
RNA-seq 大脳:2.34 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.35 骨:- 皮膚:-
EST 子宮:300.70 胎盤:185.80 前立腺:225.30 卵巣:111.80 精巣:30.30 心臓:229.90 骨格筋:180.80 食道:- 胃:276.10 腸:129.60 結腸:652.90     肝臓:137.20        肺:249.30    膀胱:251.20 腎臓:124.80 下垂体:347.90 甲状腺:- 副腎:101.60 膵臓:329 乳腺:613.30 唾液腺:-
GeneChip 子宮:10.15 胎盤:9.68 前立腺:10.13 卵巣:9.95 精巣:9.44 心臓:9.50 骨格筋:8.99 食道:10.74 胃:9.72 腸:9.66 結腸:10.04 肝臓:9.03 肺:10.12 膀胱:- 腎臓:9.65 下垂体:9.37 甲状腺:9.88 副腎:9.56 膵臓:8.67 乳腺:10.26 唾液腺:9.35
CAGE 子宮:4.70 胎盤:4.60 前立腺:4.59 卵巣:4.78 精巣:4.53 心臓:4.44 骨格筋:4.69 食道:4.84 胃:- 腸:4.67 結腸:4.67     肝臓:4.53    肺:4.79 膀胱:4.91 腎臓:4.62 下垂体:4.55 甲状腺:4.54 副腎:- 膵臓:4.28 乳腺:4.56 唾液腺:4.45
RNA-seq 子宮:- 胎盤:- 前立腺:4.66 卵巣:5.01 精巣:2.99 心臓:3.08 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:3.34     肝臓:2.35        肺:3.33    膀胱:- 腎臓:3.58 下垂体:- 甲状腺:6.31 副腎:4.08 膵臓:- 乳腺:4.04 唾液腺:-

IDs

Refseq ID NM_018890
Gene ID 5879
Unigene ID Hs.413812
Probe set ID 208641_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000136238
GTEx ID ENSG00000136238

オーソログ対応遺伝子

マウス[2]  NM_009007
ラット[1]  NM_134366

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0030041  actin filament polymerization
GO:0048532  anatomical structure arrangement
GO:0009653  anatomical structure morphogenesis
GO:0002093  auditory receptor cell morphogenesis
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0045453  bone resorption
GO:0007155  cell adhesion
GO:0048870  cell motility
GO:0008283  cell proliferation
GO:0045216  cell-cell junction organization
GO:0007160  cell-matrix adhesion
GO:0006928  cellular component movement
GO:0021799  cerebral cortex radially oriented cell migration
GO:0090103  cochlea morphogenesis
GO:0048813  dendrite morphogenesis
GO:0021831  embryonic olfactory bulb interneuron precursor migration
GO:0043652  engulfment of apoptotic cell
GO:0003382  epithelial cell morphogenesis
GO:0006972  hyperosmotic response
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030032  lamellipodium assembly
GO:0051668  localization within membrane
GO:0002551  mast cell chemotaxis
GO:0032707  negative regulation of interleukin-23 production
GO:0048261  negative regulation of receptor-mediated endocytosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030168  platelet activation
GO:0030838  positive regulation of actin filament polymerization
GO:0043065  positive regulation of apoptosis
GO:0045740  positive regulation of DNA replication
GO:0010592  positive regulation of lamellipodium assembly
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0035025  positive regulation of Rho protein signal transduction
GO:0030334  regulation of cell migration
GO:0050690  regulation of defense response to virus by virus
GO:0010310  regulation of hydrogen peroxide metabolic process
GO:0060263  regulation of respiratory burst
GO:0009611  response to wounding
GO:0031529  ruffle organization
GO:0007264  small GTPase mediated signal transduction
GO:0034446  substrate adhesion-dependent cell spreading
GO:0031295  T cell costimulation
GO:0016032  viral reproduction
GO:0060071  Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0005829  cytosol
GO:0019897  extrinsic to plasma membrane
GO:0000139  Golgi membrane
GO:0030027  lamellipodium
GO:0042470  melanosome
GO:0001891  phagocytic cup
GO:0005886  plasma membrane
GO:0032587  ruffle membrane
GO:0005802  trans-Golgi network

Molecular Function

GO:0019899  enzyme binding
GO:0005525  GTP binding
GO:0030742  GTP-dependent protein binding
GO:0003924  GTPase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0017137  Rab GTPase binding
GO:0031996  thioesterase binding