ribosomal protein S6 kinase, 70kDa, polypeptide 1

詳細情報を見る

同義遺伝子名

Ribosomal protein S6 kinase beta-1, STK14A, RPS6KB1, p70-alpha, S6K1, Ribosomal protein S6 kinase I, 70 kDa ribosomal protein S6 kinase 1, p70(S6K)-alpha, PS6K, ribosomal protein S6 kinase, 70kDa, polypeptide 1, p70-S6K, P70S6K, S6K, p70 S6 kinase alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:33.20 小脳:12.60 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:112.30 網膜:- 目:41.10 動脈:60 静脈:- リンパ節:151.70 末梢血:54.70 脾臓:18.90 胸腺:- 骨髄:19.70 脂肪:- 骨:25.60 皮膚:43.20
GeneChip 大脳:4.74 小脳:4.55 脳幹:4.70 脳梁:4.96 松果体:- 末梢神経:5.15 脊柱:4.74 網膜:- 目:- 動脈:5.20 静脈:5.07 リンパ節:5.42 末梢血:- 脾臓:5.46 胸腺:6.19 骨髄:5.29 脂肪:5.30 骨:- 皮膚:5.17
CAGE 大脳:4.01 小脳:- 脳幹:4.10 脳梁:3.75 松果体:4.03 末梢神経:- 脊柱:4.20 網膜:- 目:- 動脈:3.69 静脈:3.98 リンパ節:3.68 末梢血:- 脾臓:3.99 胸腺:3.84 骨髄:- 脂肪:4.03 骨:- 皮膚:-
RNA-seq 大脳:2.98 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.82 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.13 骨:- 皮膚:-
EST 子宮:18.20 胎盤:51 前立腺:45.10 卵巣:- 精巣:38.90 心臓:51.10 骨格筋:20.10 食道:- 胃:21.20 腸:- 結腸:50.90     肝臓:42.20        肺:48.90    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:50.80 膵臓:44.50 乳腺:213.70 唾液腺:328.40
GeneChip 子宮:5.66 胎盤:5.71 前立腺:5.64 卵巣:5.66 精巣:4.64 心臓:5.17 骨格筋:5.40 食道:5.62 胃:5.30 腸:5.23 結腸:4.38 肝臓:5.26 肺:5.37 膀胱:- 腎臓:4.47 下垂体:4.85 甲状腺:5.28 副腎:5.15 膵臓:4.77 乳腺:5.35 唾液腺:4.51
CAGE 子宮:4.15 胎盤:3.96 前立腺:3.93 卵巣:3.86 精巣:3.55 心臓:3.93 骨格筋:4.68 食道:3.92 胃:- 腸:3.71 結腸:3.83     肝臓:3.91    肺:3.69 膀胱:4.06 腎臓:3.61 下垂体:4.11 甲状腺:3.44 副腎:- 膵臓:3.61 乳腺:3.60 唾液腺:3.77
RNA-seq 子宮:- 胎盤:- 前立腺:3.29 卵巣:3.51 精巣:2.74 心臓:2.76 骨格筋:3.46 食道:- 胃:- 腸:- 結腸:2.62     肝臓:2.50        肺:2.99    膀胱:- 腎臓:2.57 下垂体:- 甲状腺:3.53 副腎:3.07 膵臓:- 乳腺:3.36 唾液腺:-

IDs

Refseq ID NM_003161
Gene ID 6198
Unigene ID Hs.463642
Probe set ID 204171_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000108443
GTEx ID ENSG00000108443

オーソログ対応遺伝子

マウス[6]  NM_001114334, NM_028259
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1922062
8871403
9271440
9427642
9445476
9465032
9653190
9804755
10089566
10197603
10200280
10567431
10601311
10807185
10971657
10973943
11013237
11171059
11279232
11297520
11331760
11438723
11500364
11516946
11733037
11774034
11853558
11914378
12014987
12019261
12023960
12052877
12054624
12150925
12150926
12477932
12529391
12586835
12604610
12718876
12733712
12747804
12759354
12801526
12869548
14673156
14679009
14702039
14709557
15024086
15028555
15066126
15071500
15149849
15158097
15203190
15236312
15249583
15304500
15314020
15319361
15341740
15342556
15474452
15533996
15589845
15623621
15659381
15692808
15696579
15723049
15790787
15809305
15812314
15843522
15854902
15896331
15899889
15905173
15953364
16049009
16109716
16183647
16262259
16286006
16364302
16407298
16434552
16469801
16640565
16715128
16763566
16810323
16818690
16826166
16837165
16839745
16883576
16895915
16899564
16914728
16922504
16931574
16962100
16964243
17043309
17045920
17052453
17053147
17081983
17255101
17310252
17336708
17386266
17427199
17512525
17569770
17599906
17604271
17616691
17622239
17693255
17908691
17936702
18025271
18279656
18423201
18451027
18461003
18505677
18565837
18652687
18660489
18813808
18829578
18952604
19065636
19085255
19112174
19168580
19240722
19266162
19285034
19322201
19553685
19730801
19801633
19815051
19864428
19881535
19889638
19913121
19914247
19936974
19953087
19961954
19995915
20137651
20157535
20173664
20187284
20190034
20374740
20410302
20423989
20433920
20459645
20599538
20599721
20617335
20628086
20657550
20731018
20819778
20932932
20953835
20961652
21035469
21048031
21067588
21071439
21093473
21184268
21224254
21228102
21258406
21289241
21292829
21297943
21390332
21397856
21424608
21440577
21444676
21460630
21467264
21536668
21541441
21561857
21602892
21609291
21710263
21757621
21832049
21833088
21900206
21981924
21986499
21988832
22110663
22113269
22248270
22286763
22348058
22391570
22439934
22442669
22457523
22493283
22544753
22574368
22645648
22684641
22705322
22795649
22871496
22939624
22977662
23044732
23045529
23128233
23184942
23251661
23273915
23276696
23330000
23376066
23393338
23632629
23639457
23731517
23739915
23816567
23886172
23938603
24023352
24030155
24067973
24089522
24157791
24247430
24250222
24277938
24337579
24440085
24456794
24501087
24606695
24652283
24675012
24729449
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007568  aging
GO:0006915  apoptosis
GO:0016477  cell migration
GO:0071363  cellular response to growth factor stimulus
GO:0000082  G1/S transition of mitotic cell cycle
GO:0007281  germ cell development
GO:0008286  insulin receptor signaling pathway
GO:0007616  long-term memory
GO:0043066  negative regulation of apoptosis
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0048015  phosphoinositide-mediated signaling
GO:0045931  positive regulation of mitotic cell cycle
GO:0048633  positive regulation of skeletal muscle tissue growth
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045727  positive regulation of translation
GO:0045948  positive regulation of translational initiation
GO:0006468  protein amino acid phosphorylation
GO:0043491  protein kinase B signaling cascade
GO:0046324  regulation of glucose import
GO:0042493  response to drug
GO:0014878  response to electrical stimulus involved in regulation of muscle adaptation
GO:0045471  response to ethanol
GO:0033762  response to glucagon stimulus
GO:0051384  response to glucocorticoid stimulus
GO:0009749  response to glucose stimulus
GO:0009408  response to heat
GO:0043201  response to leucine
GO:0032496  response to lipopolysaccharide
GO:0009612  response to mechanical stimulus
GO:0007584  response to nutrient
GO:0033574  response to testosterone stimulus
GO:0009636  response to toxin
GO:0034612  response to tumor necrosis factor
GO:0009611  response to wounding
GO:0007165  signal transduction
GO:0014732  skeletal muscle atrophy
GO:0003009  skeletal muscle contraction
GO:0031929  TOR signaling pathway

Cellular Component

GO:0030054  cell junction
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0045202  synapse

Molecular Function

GO:0005524  ATP binding
GO:0042277  peptide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004711  ribosomal protein S6 kinase activity