ribosomal protein S6 kinase, 70kDa, polypeptide 1

同義遺伝子名

Ribosomal protein S6 kinase beta-1, STK14A, RPS6KB1, p70-alpha, S6K1, Ribosomal protein S6 kinase I, 70 kDa ribosomal protein S6 kinase 1, p70(S6K)-alpha, PS6K, ribosomal protein S6 kinase, 70kDa, polypeptide 1, p70-S6K, P70S6K, S6K, p70 S6 kinase alpha

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:33.20

小脳:12.60

脳幹:-

脳梁:-

松果体:-

末梢神経:30.70

脊柱:112.30

網膜:-

目:41.10

動脈:60

静脈:-

リンパ節:151.70

末梢血:54.70

脾臓:18.90

胸腺:-

骨髄:19.70

脂肪:-

骨:25.60

皮膚:43.20

GeneChip

大脳:5.21

小脳:5.23

脳幹:5.25

脳梁:5.23

松果体:-

末梢神経:5.14

脊柱:5.05

網膜:-

目:-

動脈:5.21

静脈:5.56

リンパ節:5.25

末梢血:-

脾臓:5.37

胸腺:5.73

骨髄:5.39

脂肪:5.44

骨:-

皮膚:5.50

CAGE

大脳:4.01

小脳:-

脳幹:4.10

脳梁:3.75

松果体:4.03

末梢神経:-

脊柱:4.20

網膜:-

目:-

動脈:3.69

静脈:3.98

リンパ節:3.68

末梢血:-

脾臓:3.99

胸腺:3.84

骨髄:-

脂肪:4.03

骨:-

皮膚:-

RNA-seq

大脳:2.98

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.82

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.13

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:51

前立腺:45.10

卵巣:-

精巣:38.90

心臓:51.10

骨格筋:20.10

食道:-

胃:21.20

腸:-

結腸:50.90

肝臓:42.20

肺:48.90

膀胱:-

腎臓:41.60

下垂体:-

甲状腺:-

副腎:50.80

膵臓:44.50

乳腺:213.70

唾液腺:328.40

GeneChip

子宮:5.64

胎盤:5.35

前立腺:5.33

卵巣:5.71

精巣:5.15

心臓:5.43

骨格筋:5.49

食道:5.65

胃:5.34

腸:5.54

結腸:5.34

肝臓:5.06

肺:5.18

膀胱:-

腎臓:5.13

下垂体:5.10

甲状腺:4.88

副腎:5.13

膵臓:5.89

乳腺:5.29

唾液腺:4.97

CAGE

子宮:4.15

胎盤:3.96

前立腺:3.93

卵巣:3.86

精巣:3.55

心臓:3.93

骨格筋:4.68

食道:3.92

胃:-

腸:3.71

結腸:3.83

肝臓:3.91

肺:3.69

膀胱:4.06

腎臓:3.61

下垂体:4.11

甲状腺:3.44

副腎:-

膵臓:3.61

乳腺:3.60

唾液腺:3.77

RNA-seq

子宮:-

胎盤:-

前立腺:3.29

卵巣:3.51

精巣:2.74

心臓:2.76

骨格筋:3.46

食道:-

胃:-

腸:-

結腸:2.62

肝臓:2.50

肺:2.99

膀胱:-

腎臓:2.57

下垂体:-

甲状腺:3.53

副腎:3.07

膵臓:-

乳腺:3.36

唾液腺:-

IDs

Refseq ID	NM_003161
Gene ID	6198
Unigene ID	Hs.463642
Probe set ID	211578_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000108443
GTEx ID	ENSG00000108443

オーソログ対応遺伝子

マウス[6]	NM_001114334, NM_028259
ラット [0]

染色体

17q23.1 [57,970,447 - 58,027,925]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007568	aging
GO:0006915	apoptosis
GO:0016477	cell migration
GO:0071363	cellular response to growth factor stimulus
GO:0000082	G1/S transition of mitotic cell cycle
GO:0007281	germ cell development
GO:0008286	insulin receptor signaling pathway
GO:0007616	long-term memory
GO:0043066	negative regulation of apoptosis
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0048015	phosphoinositide-mediated signaling
GO:0045931	positive regulation of mitotic cell cycle
GO:0048633	positive regulation of skeletal muscle tissue growth
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045727	positive regulation of translation
GO:0045948	positive regulation of translational initiation
GO:0006468	protein amino acid phosphorylation
GO:0043491	protein kinase B signaling cascade
GO:0046324	regulation of glucose import
GO:0042493	response to drug
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation
GO:0045471	response to ethanol
GO:0033762	response to glucagon stimulus
GO:0051384	response to glucocorticoid stimulus
GO:0009749	response to glucose stimulus
GO:0009408	response to heat
GO:0043201	response to leucine
GO:0032496	response to lipopolysaccharide
GO:0009612	response to mechanical stimulus
GO:0007584	response to nutrient
GO:0033574	response to testosterone stimulus
GO:0009636	response to toxin
GO:0034612	response to tumor necrosis factor
GO:0009611	response to wounding
GO:0007165	signal transduction
GO:0014732	skeletal muscle atrophy
GO:0003009	skeletal muscle contraction
GO:0031929	TOR signaling pathway

Cellular Component

GO:0030054	cell junction
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0045202	synapse

Molecular Function

GO:0005524	ATP binding
GO:0042277	peptide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004711	ribosomal protein S6 kinase activity

ribosomal protein S6 kinase, 70kDa, polypeptide 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function